| Full name: G protein-coupled receptor 31 | Alias Symbol: HETER1|12-HETER | ||
| Type: protein-coding gene | Cytoband: 6q27 | ||
| Entrez ID: 2853 | HGNC ID: HGNC:4486 | Ensembl Gene: ENSG00000120436 | OMIM ID: 602043 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR31:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR31 | 2853 | 208556_at | 0.0195 | 0.9553 | |
| GSE20347 | GPR31 | 2853 | 208556_at | -0.0225 | 0.8453 | |
| GSE23400 | GPR31 | 2853 | 208556_at | -0.0861 | 0.0105 | |
| GSE26886 | GPR31 | 2853 | 208556_at | -0.0749 | 0.4711 | |
| GSE29001 | GPR31 | 2853 | 208556_at | -0.1758 | 0.2653 | |
| GSE38129 | GPR31 | 2853 | 208556_at | -0.1223 | 0.1776 | |
| GSE45670 | GPR31 | 2853 | 208556_at | -0.1218 | 0.2842 | |
| GSE53622 | GPR31 | 2853 | 25530 | -0.1064 | 0.0360 | |
| GSE53624 | GPR31 | 2853 | 25530 | -0.0980 | 0.0848 | |
| GSE63941 | GPR31 | 2853 | 208556_at | 0.2980 | 0.0675 | |
| GSE77861 | GPR31 | 2853 | 208556_at | -0.1461 | 0.2992 | |
| GSE97050 | GPR31 | 2853 | A_33_P3375358 | -0.1733 | 0.4734 | |
| TCGA | GPR31 | 2853 | RNAseq | -1.1625 | 0.3804 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GPR31 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR31:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR31 | 2853 | 2 | 6 | 22 | |
| GSE20123 | GPR31 | 2853 | 2 | 6 | 22 | |
| GSE43470 | GPR31 | 2853 | 3 | 0 | 40 | |
| GSE46452 | GPR31 | 2853 | 3 | 10 | 46 | |
| GSE47630 | GPR31 | 2853 | 7 | 7 | 26 | |
| GSE54993 | GPR31 | 2853 | 4 | 3 | 63 | |
| GSE54994 | GPR31 | 2853 | 10 | 8 | 35 | |
| GSE60625 | GPR31 | 2853 | 1 | 1 | 9 | |
| GSE74703 | GPR31 | 2853 | 3 | 0 | 33 | |
| GSE74704 | GPR31 | 2853 | 1 | 3 | 16 | |
| TCGA | GPR31 | 2853 | 14 | 21 | 61 |
Total number of gains: 50; Total number of losses: 65; Total Number of normals: 373.
Somatic mutations of GPR31:
Generating mutation plots.
Highly correlated genes for GPR31:
Showing top 20/883 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR31 | LIMD2 | 0.753237 | 3 | 0 | 3 |
| GPR31 | TMSB4Y | 0.748367 | 3 | 0 | 3 |
| GPR31 | MYCN | 0.748249 | 3 | 0 | 3 |
| GPR31 | ARHGEF38 | 0.728155 | 5 | 0 | 5 |
| GPR31 | IL18BP | 0.72367 | 5 | 0 | 5 |
| GPR31 | LBX1 | 0.7213 | 4 | 0 | 4 |
| GPR31 | ZNF480 | 0.720866 | 3 | 0 | 3 |
| GPR31 | ITGB3 | 0.715934 | 6 | 0 | 6 |
| GPR31 | CGA | 0.713076 | 5 | 0 | 5 |
| GPR31 | ZNF747 | 0.707587 | 6 | 0 | 5 |
| GPR31 | GABRR2 | 0.707409 | 5 | 0 | 5 |
| GPR31 | UBQLN3 | 0.705646 | 5 | 0 | 5 |
| GPR31 | APBA1 | 0.703602 | 6 | 0 | 6 |
| GPR31 | HHLA1 | 0.70136 | 6 | 0 | 5 |
| GPR31 | OR6A2 | 0.698708 | 5 | 0 | 5 |
| GPR31 | GRIN2D | 0.69798 | 3 | 0 | 3 |
| GPR31 | GRK6 | 0.696013 | 4 | 0 | 4 |
| GPR31 | HAO2 | 0.695348 | 5 | 0 | 5 |
| GPR31 | RNF185-AS1 | 0.691055 | 5 | 0 | 5 |
| GPR31 | BFSP2 | 0.690912 | 5 | 0 | 5 |
For details and further investigation, click here
