| Full name: OTU deubiquitinase 7A | Alias Symbol: CEZANNE2 | ||
| Type: protein-coding gene | Cytoband: 15q13.3 | ||
| Entrez ID: 161725 | HGNC ID: HGNC:20718 | Ensembl Gene: ENSG00000169918 | OMIM ID: 612024 |
| Drug and gene relationship at DGIdb | |||
Expression of OTUD7A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OTUD7A | 161725 | 1560399_a_at | -0.0608 | 0.8452 | |
| GSE26886 | OTUD7A | 161725 | 1560399_a_at | 0.0481 | 0.7489 | |
| GSE45670 | OTUD7A | 161725 | 1560399_a_at | -0.0267 | 0.8250 | |
| GSE53622 | OTUD7A | 161725 | 20649 | 0.1331 | 0.1653 | |
| GSE53624 | OTUD7A | 161725 | 48441 | 0.1418 | 0.2191 | |
| GSE63941 | OTUD7A | 161725 | 1553351_at | 0.1934 | 0.2424 | |
| GSE77861 | OTUD7A | 161725 | 1560399_a_at | -0.2191 | 0.1049 | |
| GSE97050 | OTUD7A | 161725 | A_33_P3262376 | -0.1834 | 0.5283 | |
| SRP064894 | OTUD7A | 161725 | RNAseq | -0.2923 | 0.3754 | |
| SRP133303 | OTUD7A | 161725 | RNAseq | 0.0458 | 0.9082 | |
| SRP159526 | OTUD7A | 161725 | RNAseq | 0.4019 | 0.2649 | |
| SRP193095 | OTUD7A | 161725 | RNAseq | 0.2131 | 0.3672 | |
| SRP219564 | OTUD7A | 161725 | RNAseq | -0.4587 | 0.4126 | |
| TCGA | OTUD7A | 161725 | RNAseq | -0.2135 | 0.3993 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OTUD7A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OTUD7A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OTUD7A | 161725 | 2 | 7 | 21 | |
| GSE20123 | OTUD7A | 161725 | 2 | 7 | 21 | |
| GSE43470 | OTUD7A | 161725 | 4 | 4 | 35 | |
| GSE46452 | OTUD7A | 161725 | 3 | 7 | 49 | |
| GSE47630 | OTUD7A | 161725 | 8 | 11 | 21 | |
| GSE54993 | OTUD7A | 161725 | 4 | 6 | 60 | |
| GSE54994 | OTUD7A | 161725 | 6 | 7 | 40 | |
| GSE60625 | OTUD7A | 161725 | 4 | 0 | 7 | |
| GSE74703 | OTUD7A | 161725 | 4 | 3 | 29 | |
| GSE74704 | OTUD7A | 161725 | 1 | 6 | 13 | |
| TCGA | OTUD7A | 161725 | 16 | 17 | 63 |
Total number of gains: 54; Total number of losses: 75; Total Number of normals: 359.
Somatic mutations of OTUD7A:
Generating mutation plots.
Highly correlated genes for OTUD7A:
Showing top 20/54 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OTUD7A | KDM8 | 0.744467 | 3 | 0 | 3 |
| OTUD7A | DNAH7 | 0.676871 | 3 | 0 | 3 |
| OTUD7A | TNFRSF10C | 0.66046 | 3 | 0 | 3 |
| OTUD7A | DLGAP2-AS1 | 0.650068 | 3 | 0 | 3 |
| OTUD7A | ARHGEF25 | 0.640692 | 3 | 0 | 3 |
| OTUD7A | CHRNE | 0.635929 | 3 | 0 | 3 |
| OTUD7A | TMEM114 | 0.635813 | 4 | 0 | 3 |
| OTUD7A | ZBTB46-AS1 | 0.627149 | 3 | 0 | 3 |
| OTUD7A | SERPINA10 | 0.622591 | 3 | 0 | 3 |
| OTUD7A | LINC01281 | 0.620461 | 4 | 0 | 4 |
| OTUD7A | CCIN | 0.617195 | 4 | 0 | 3 |
| OTUD7A | NPPB | 0.617089 | 3 | 0 | 3 |
| OTUD7A | IQCF2 | 0.615575 | 5 | 0 | 5 |
| OTUD7A | GRIK1-AS1 | 0.613474 | 3 | 0 | 3 |
| OTUD7A | COX6A2 | 0.606327 | 5 | 0 | 3 |
| OTUD7A | LINC00313 | 0.605608 | 4 | 0 | 3 |
| OTUD7A | ADAM30 | 0.599798 | 3 | 0 | 3 |
| OTUD7A | NTRK3-AS1 | 0.59735 | 3 | 0 | 3 |
| OTUD7A | HGFAC | 0.597009 | 5 | 0 | 4 |
| OTUD7A | SLC4A8 | 0.593953 | 3 | 0 | 3 |
For details and further investigation, click here
