| Full name: transmembrane protein 114 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p13.2 | ||
| Entrez ID: 283953 | HGNC ID: HGNC:33227 | Ensembl Gene: ENSG00000232258 | OMIM ID: 611579 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM114:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM114 | 283953 | 231462_at | -0.2934 | 0.1516 | |
| GSE26886 | TMEM114 | 283953 | 231462_at | -0.2397 | 0.1242 | |
| GSE45670 | TMEM114 | 283953 | 231462_at | -0.0547 | 0.5328 | |
| GSE63941 | TMEM114 | 283953 | 231462_at | -0.0233 | 0.9036 | |
| GSE77861 | TMEM114 | 283953 | 231462_at | -0.2647 | 0.0231 | |
| GSE97050 | TMEM114 | 283953 | A_33_P3222947 | -0.2731 | 0.3847 | |
| SRP133303 | TMEM114 | 283953 | RNAseq | 0.1821 | 0.3034 | |
| SRP193095 | TMEM114 | 283953 | RNAseq | 0.0322 | 0.8473 | |
| TCGA | TMEM114 | 283953 | RNAseq | 1.8049 | 0.2082 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM114 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TMEM114:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM114 | 283953 | 4 | 4 | 22 | |
| GSE20123 | TMEM114 | 283953 | 4 | 3 | 23 | |
| GSE43470 | TMEM114 | 283953 | 3 | 2 | 38 | |
| GSE46452 | TMEM114 | 283953 | 38 | 1 | 20 | |
| GSE47630 | TMEM114 | 283953 | 13 | 6 | 21 | |
| GSE54993 | TMEM114 | 283953 | 3 | 5 | 62 | |
| GSE54994 | TMEM114 | 283953 | 5 | 9 | 39 | |
| GSE60625 | TMEM114 | 283953 | 4 | 0 | 7 | |
| GSE74703 | TMEM114 | 283953 | 3 | 2 | 31 | |
| GSE74704 | TMEM114 | 283953 | 2 | 1 | 17 | |
| TCGA | TMEM114 | 283953 | 20 | 13 | 63 |
Total number of gains: 99; Total number of losses: 46; Total Number of normals: 343.
Somatic mutations of TMEM114:
Generating mutation plots.
Highly correlated genes for TMEM114:
Showing top 20/426 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM114 | PINK1 | 0.80486 | 3 | 0 | 3 |
| TMEM114 | POU6F1 | 0.751362 | 4 | 0 | 4 |
| TMEM114 | LPAR1 | 0.743532 | 3 | 0 | 3 |
| TMEM114 | ICA1L | 0.740046 | 3 | 0 | 3 |
| TMEM114 | MKRN2 | 0.733102 | 3 | 0 | 3 |
| TMEM114 | ARHGAP44 | 0.73065 | 3 | 0 | 3 |
| TMEM114 | F10 | 0.727459 | 3 | 0 | 3 |
| TMEM114 | COBL | 0.723761 | 3 | 0 | 3 |
| TMEM114 | CCNG1 | 0.721146 | 3 | 0 | 3 |
| TMEM114 | MTUS2 | 0.72084 | 3 | 0 | 3 |
| TMEM114 | MSRA | 0.714548 | 3 | 0 | 3 |
| TMEM114 | EIF4E3 | 0.711322 | 3 | 0 | 3 |
| TMEM114 | RPL29 | 0.711171 | 3 | 0 | 3 |
| TMEM114 | KIF1B | 0.709945 | 3 | 0 | 3 |
| TMEM114 | POLN | 0.708451 | 3 | 0 | 3 |
| TMEM114 | ISOC1 | 0.705684 | 3 | 0 | 3 |
| TMEM114 | NHSL2 | 0.703409 | 3 | 0 | 3 |
| TMEM114 | MTMR10 | 0.700056 | 3 | 0 | 3 |
| TMEM114 | FYCO1 | 0.698809 | 3 | 0 | 3 |
| TMEM114 | LINC00470 | 0.698805 | 3 | 0 | 3 |
For details and further investigation, click here
