| Full name: dynein axonemal heavy chain 7 | Alias Symbol: KIAA0944 | ||
| Type: protein-coding gene | Cytoband: 2q32.3 | ||
| Entrez ID: 56171 | HGNC ID: HGNC:18661 | Ensembl Gene: ENSG00000118997 | OMIM ID: 610061 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAH7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAH7 | 56171 | 234476_at | -0.0055 | 0.9847 | |
| GSE20347 | DNAH7 | 56171 | 214222_at | 0.0186 | 0.8363 | |
| GSE23400 | DNAH7 | 56171 | 214222_at | -0.0713 | 0.0117 | |
| GSE26886 | DNAH7 | 56171 | 214222_at | -0.1389 | 0.3589 | |
| GSE29001 | DNAH7 | 56171 | 214222_at | -0.0580 | 0.7500 | |
| GSE38129 | DNAH7 | 56171 | 214222_at | -0.1119 | 0.1948 | |
| GSE45670 | DNAH7 | 56171 | 214222_at | -0.0883 | 0.3746 | |
| GSE53622 | DNAH7 | 56171 | 728 | 0.1843 | 0.2531 | |
| GSE53624 | DNAH7 | 56171 | 728 | -0.2013 | 0.0541 | |
| GSE63941 | DNAH7 | 56171 | 234476_at | 0.0185 | 0.9363 | |
| GSE77861 | DNAH7 | 56171 | 214222_at | -0.2702 | 0.0431 | |
| GSE97050 | DNAH7 | 56171 | A_32_P351037 | 0.0236 | 0.9469 | |
| SRP133303 | DNAH7 | 56171 | RNAseq | -0.0731 | 0.8844 | |
| TCGA | DNAH7 | 56171 | RNAseq | -1.7407 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DNAH7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAH7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAH7 | 56171 | 8 | 3 | 19 | |
| GSE20123 | DNAH7 | 56171 | 8 | 3 | 19 | |
| GSE43470 | DNAH7 | 56171 | 3 | 1 | 39 | |
| GSE46452 | DNAH7 | 56171 | 1 | 4 | 54 | |
| GSE47630 | DNAH7 | 56171 | 4 | 5 | 31 | |
| GSE54993 | DNAH7 | 56171 | 0 | 4 | 66 | |
| GSE54994 | DNAH7 | 56171 | 11 | 7 | 35 | |
| GSE60625 | DNAH7 | 56171 | 0 | 3 | 8 | |
| GSE74703 | DNAH7 | 56171 | 2 | 1 | 33 | |
| GSE74704 | DNAH7 | 56171 | 3 | 2 | 15 | |
| TCGA | DNAH7 | 56171 | 22 | 9 | 65 |
Total number of gains: 62; Total number of losses: 42; Total Number of normals: 384.
Somatic mutations of DNAH7:
Generating mutation plots.
Highly correlated genes for DNAH7:
Showing top 20/251 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAH7 | SCARF1 | 0.727406 | 3 | 0 | 3 |
| DNAH7 | VASH1 | 0.708952 | 3 | 0 | 3 |
| DNAH7 | PTGIS | 0.708398 | 3 | 0 | 3 |
| DNAH7 | CHMP2A | 0.691539 | 3 | 0 | 3 |
| DNAH7 | NDUFA11 | 0.689435 | 3 | 0 | 3 |
| DNAH7 | OTUD7A | 0.676871 | 3 | 0 | 3 |
| DNAH7 | CLCN7 | 0.67198 | 3 | 0 | 3 |
| DNAH7 | KLHL2 | 0.668271 | 3 | 0 | 3 |
| DNAH7 | STX18 | 0.663752 | 3 | 0 | 3 |
| DNAH7 | TMEM59 | 0.663181 | 3 | 0 | 3 |
| DNAH7 | RPH3AL | 0.662999 | 3 | 0 | 3 |
| DNAH7 | FANCA | 0.662719 | 3 | 0 | 3 |
| DNAH7 | CYTH4 | 0.653491 | 3 | 0 | 3 |
| DNAH7 | GNG8 | 0.653033 | 3 | 0 | 3 |
| DNAH7 | BRK1 | 0.648894 | 3 | 0 | 3 |
| DNAH7 | MMD2 | 0.648108 | 3 | 0 | 3 |
| DNAH7 | RAB25 | 0.647687 | 3 | 0 | 3 |
| DNAH7 | SH3GLB1 | 0.646814 | 3 | 0 | 3 |
| DNAH7 | ACTR1A | 0.645216 | 3 | 0 | 3 |
| DNAH7 | NDUFB11 | 0.644015 | 3 | 0 | 3 |
For details and further investigation, click here
