| Full name: cytohesin 3 | Alias Symbol: GRP1|ARNO3|cytohesin-3 | ||
| Type: protein-coding gene | Cytoband: 7p22.1 | ||
| Entrez ID: 9265 | HGNC ID: HGNC:9504 | Ensembl Gene: ENSG00000008256 | OMIM ID: 605081 |
| Drug and gene relationship at DGIdb | |||
CYTH3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04072 | Phospholipase D signaling pathway |
Expression of CYTH3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYTH3 | 9265 | 225147_at | -0.1454 | 0.7899 | |
| GSE20347 | CYTH3 | 9265 | 206523_at | 0.0223 | 0.7238 | |
| GSE23400 | CYTH3 | 9265 | 206523_at | 0.0085 | 0.7967 | |
| GSE26886 | CYTH3 | 9265 | 225147_at | 0.9367 | 0.0004 | |
| GSE29001 | CYTH3 | 9265 | 206523_at | 0.2713 | 0.0370 | |
| GSE38129 | CYTH3 | 9265 | 206523_at | 0.0075 | 0.9020 | |
| GSE45670 | CYTH3 | 9265 | 225147_at | -0.4922 | 0.0042 | |
| GSE53622 | CYTH3 | 9265 | 63392 | 0.0550 | 0.5351 | |
| GSE53624 | CYTH3 | 9265 | 63392 | 0.2000 | 0.0072 | |
| GSE63941 | CYTH3 | 9265 | 225147_at | -1.0170 | 0.0662 | |
| GSE77861 | CYTH3 | 9265 | 225147_at | 0.1391 | 0.3604 | |
| GSE97050 | CYTH3 | 9265 | A_33_P3271051 | -0.0802 | 0.7079 | |
| SRP007169 | CYTH3 | 9265 | RNAseq | 0.9238 | 0.0422 | |
| SRP008496 | CYTH3 | 9265 | RNAseq | 1.3392 | 0.0002 | |
| SRP064894 | CYTH3 | 9265 | RNAseq | 0.1081 | 0.5524 | |
| SRP133303 | CYTH3 | 9265 | RNAseq | 0.0533 | 0.8062 | |
| SRP159526 | CYTH3 | 9265 | RNAseq | -0.0723 | 0.7726 | |
| SRP193095 | CYTH3 | 9265 | RNAseq | 0.3420 | 0.0598 | |
| SRP219564 | CYTH3 | 9265 | RNAseq | 0.0127 | 0.9724 | |
| TCGA | CYTH3 | 9265 | RNAseq | -0.0625 | 0.2592 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CYTH3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYTH3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYTH3 | 9265 | 14 | 1 | 15 | |
| GSE20123 | CYTH3 | 9265 | 14 | 1 | 15 | |
| GSE43470 | CYTH3 | 9265 | 6 | 1 | 36 | |
| GSE46452 | CYTH3 | 9265 | 13 | 1 | 45 | |
| GSE47630 | CYTH3 | 9265 | 9 | 1 | 30 | |
| GSE54993 | CYTH3 | 9265 | 0 | 6 | 64 | |
| GSE54994 | CYTH3 | 9265 | 20 | 1 | 32 | |
| GSE60625 | CYTH3 | 9265 | 0 | 0 | 11 | |
| GSE74703 | CYTH3 | 9265 | 6 | 0 | 30 | |
| GSE74704 | CYTH3 | 9265 | 9 | 0 | 11 | |
| TCGA | CYTH3 | 9265 | 55 | 5 | 36 |
Total number of gains: 146; Total number of losses: 17; Total Number of normals: 325.
Somatic mutations of CYTH3:
Generating mutation plots.
Highly correlated genes for CYTH3:
Showing top 20/700 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYTH3 | LRRC40 | 0.788858 | 3 | 0 | 3 |
| CYTH3 | KLC1 | 0.772664 | 4 | 0 | 4 |
| CYTH3 | KLHL31 | 0.76721 | 3 | 0 | 3 |
| CYTH3 | TNFRSF10B | 0.765974 | 3 | 0 | 3 |
| CYTH3 | TWISTNB | 0.758559 | 3 | 0 | 3 |
| CYTH3 | C16orf58 | 0.751511 | 3 | 0 | 3 |
| CYTH3 | WDR54 | 0.750937 | 3 | 0 | 3 |
| CYTH3 | AXL | 0.750569 | 4 | 0 | 4 |
| CYTH3 | TANC2 | 0.744415 | 4 | 0 | 4 |
| CYTH3 | UAP1 | 0.741387 | 3 | 0 | 3 |
| CYTH3 | ETS2 | 0.740956 | 3 | 0 | 3 |
| CYTH3 | TOR1B | 0.739738 | 3 | 0 | 3 |
| CYTH3 | C9orf78 | 0.739388 | 3 | 0 | 3 |
| CYTH3 | LILRB2 | 0.738504 | 3 | 0 | 3 |
| CYTH3 | ACY1 | 0.738452 | 3 | 0 | 3 |
| CYTH3 | STC2 | 0.738077 | 4 | 0 | 4 |
| CYTH3 | FAF2 | 0.737998 | 3 | 0 | 3 |
| CYTH3 | TM2D3 | 0.736048 | 3 | 0 | 3 |
| CYTH3 | SUMF2 | 0.732548 | 3 | 0 | 3 |
| CYTH3 | SF3B2 | 0.726356 | 3 | 0 | 3 |
For details and further investigation, click here
