| Full name: MAX network transcriptional repressor | Alias Symbol: ROX|MXD6|MAD6|bHLHd3 | ||
| Type: protein-coding gene | Cytoband: 17p13.3 | ||
| Entrez ID: 4335 | HGNC ID: HGNC:7188 | Ensembl Gene: ENSG00000070444 | OMIM ID: 603039 |
| Drug and gene relationship at DGIdb | |||
Expression of MNT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MNT | 4335 | 204206_at | 0.3565 | 0.4709 | |
| GSE20347 | MNT | 4335 | 204206_at | -0.2149 | 0.3020 | |
| GSE23400 | MNT | 4335 | 204206_at | -0.1891 | 0.0128 | |
| GSE26886 | MNT | 4335 | 204206_at | 0.9506 | 0.0000 | |
| GSE29001 | MNT | 4335 | 204206_at | -0.2234 | 0.4782 | |
| GSE38129 | MNT | 4335 | 204206_at | -0.1614 | 0.2415 | |
| GSE45670 | MNT | 4335 | 204206_at | -0.2900 | 0.0592 | |
| GSE53622 | MNT | 4335 | 42903 | -0.2671 | 0.0007 | |
| GSE53624 | MNT | 4335 | 42903 | 0.0005 | 0.9947 | |
| GSE63941 | MNT | 4335 | 204206_at | 0.2420 | 0.5042 | |
| GSE77861 | MNT | 4335 | 204206_at | 0.3515 | 0.0655 | |
| GSE97050 | MNT | 4335 | A_33_P3246733 | 0.0077 | 0.9780 | |
| SRP007169 | MNT | 4335 | RNAseq | 0.6958 | 0.1973 | |
| SRP008496 | MNT | 4335 | RNAseq | 0.2709 | 0.4367 | |
| SRP064894 | MNT | 4335 | RNAseq | -0.1782 | 0.4362 | |
| SRP133303 | MNT | 4335 | RNAseq | -0.3430 | 0.1054 | |
| SRP159526 | MNT | 4335 | RNAseq | -0.2798 | 0.4625 | |
| SRP193095 | MNT | 4335 | RNAseq | 0.2412 | 0.1951 | |
| SRP219564 | MNT | 4335 | RNAseq | -0.1219 | 0.7428 | |
| TCGA | MNT | 4335 | RNAseq | 0.0617 | 0.2197 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MNT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MNT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MNT | 4335 | 4 | 2 | 24 | |
| GSE20123 | MNT | 4335 | 4 | 3 | 23 | |
| GSE43470 | MNT | 4335 | 1 | 6 | 36 | |
| GSE46452 | MNT | 4335 | 34 | 1 | 24 | |
| GSE47630 | MNT | 4335 | 7 | 1 | 32 | |
| GSE54993 | MNT | 4335 | 4 | 3 | 63 | |
| GSE54994 | MNT | 4335 | 6 | 9 | 38 | |
| GSE60625 | MNT | 4335 | 4 | 0 | 7 | |
| GSE74703 | MNT | 4335 | 1 | 3 | 32 | |
| GSE74704 | MNT | 4335 | 2 | 1 | 17 | |
| TCGA | MNT | 4335 | 18 | 22 | 56 |
Total number of gains: 85; Total number of losses: 51; Total Number of normals: 352.
Somatic mutations of MNT:
Generating mutation plots.
Highly correlated genes for MNT:
Showing top 20/498 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MNT | MAST2 | 0.799204 | 3 | 0 | 3 |
| MNT | LIN37 | 0.773608 | 3 | 0 | 3 |
| MNT | ALKBH6 | 0.773131 | 4 | 0 | 4 |
| MNT | CHERP | 0.757758 | 3 | 0 | 3 |
| MNT | GRAMD1A | 0.755343 | 3 | 0 | 3 |
| MNT | KLC2 | 0.754713 | 3 | 0 | 3 |
| MNT | SSBP4 | 0.751377 | 3 | 0 | 3 |
| MNT | SRA1 | 0.747164 | 3 | 0 | 3 |
| MNT | CPSF7 | 0.746231 | 3 | 0 | 3 |
| MNT | MYBBP1A | 0.739237 | 3 | 0 | 3 |
| MNT | KLF7 | 0.733417 | 3 | 0 | 3 |
| MNT | RILPL1 | 0.730074 | 3 | 0 | 3 |
| MNT | HSPG2 | 0.721754 | 3 | 0 | 3 |
| MNT | MSTO1 | 0.714604 | 4 | 0 | 4 |
| MNT | ZNF358 | 0.714103 | 3 | 0 | 3 |
| MNT | CCM2 | 0.712664 | 3 | 0 | 3 |
| MNT | GALNT6 | 0.712045 | 3 | 0 | 3 |
| MNT | ZNF628 | 0.708193 | 3 | 0 | 3 |
| MNT | SP110 | 0.707636 | 3 | 0 | 3 |
| MNT | MYH10 | 0.707156 | 4 | 0 | 4 |
For details and further investigation, click here
