| Full name: small integral membrane protein 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 643008 | HGNC ID: HGNC:40030 | Ensembl Gene: ENSG00000204323 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SMIM5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMIM5 | 643008 | 229740_at | -1.6868 | 0.0289 | |
| GSE26886 | SMIM5 | 643008 | 229740_at | -1.7954 | 0.0000 | |
| GSE45670 | SMIM5 | 643008 | 229740_at | -1.1928 | 0.0018 | |
| GSE53622 | SMIM5 | 643008 | 24135 | -3.4473 | 0.0000 | |
| GSE53624 | SMIM5 | 643008 | 24135 | -4.0916 | 0.0000 | |
| GSE63941 | SMIM5 | 643008 | 229740_at | 0.3946 | 0.1415 | |
| GSE77861 | SMIM5 | 643008 | 229740_at | -1.2051 | 0.0715 | |
| SRP007169 | SMIM5 | 643008 | RNAseq | -4.3182 | 0.0000 | |
| SRP008496 | SMIM5 | 643008 | RNAseq | -4.4683 | 0.0000 | |
| SRP064894 | SMIM5 | 643008 | RNAseq | -3.6032 | 0.0000 | |
| SRP133303 | SMIM5 | 643008 | RNAseq | -2.7212 | 0.0000 | |
| SRP159526 | SMIM5 | 643008 | RNAseq | -3.8675 | 0.0000 | |
| SRP193095 | SMIM5 | 643008 | RNAseq | -2.7806 | 0.0000 | |
| SRP219564 | SMIM5 | 643008 | RNAseq | -3.5378 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by SMIM5 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SMIM5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMIM5 | 643008 | 7 | 2 | 21 | |
| GSE20123 | SMIM5 | 643008 | 7 | 2 | 21 | |
| GSE43470 | SMIM5 | 643008 | 5 | 3 | 35 | |
| GSE46452 | SMIM5 | 643008 | 34 | 0 | 25 | |
| GSE47630 | SMIM5 | 643008 | 8 | 1 | 31 | |
| GSE54993 | SMIM5 | 643008 | 2 | 5 | 63 | |
| GSE54994 | SMIM5 | 643008 | 10 | 4 | 39 | |
| GSE60625 | SMIM5 | 643008 | 6 | 0 | 5 | |
| GSE74703 | SMIM5 | 643008 | 5 | 1 | 30 | |
| GSE74704 | SMIM5 | 643008 | 5 | 1 | 14 | |
| TCGA | SMIM5 | 643008 | 32 | 9 | 55 |
Total number of gains: 121; Total number of losses: 28; Total Number of normals: 339.
Somatic mutations of SMIM5:
Generating mutation plots.
Highly correlated genes for SMIM5:
Showing top 20/1553 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMIM5 | SCNN1B | 0.907622 | 6 | 0 | 6 |
| SMIM5 | FAM3D | 0.904739 | 6 | 0 | 6 |
| SMIM5 | KRT78 | 0.884063 | 6 | 0 | 6 |
| SMIM5 | RANBP9 | 0.879393 | 6 | 0 | 6 |
| SMIM5 | PLEKHM1 | 0.876333 | 6 | 0 | 6 |
| SMIM5 | SASH1 | 0.875541 | 6 | 0 | 6 |
| SMIM5 | EMP1 | 0.872186 | 6 | 0 | 6 |
| SMIM5 | ECM1 | 0.871861 | 6 | 0 | 6 |
| SMIM5 | CAPN5 | 0.871165 | 6 | 0 | 6 |
| SMIM5 | SPINK7 | 0.870948 | 6 | 0 | 6 |
| SMIM5 | FAM214A | 0.867409 | 6 | 0 | 6 |
| SMIM5 | KALRN | 0.864305 | 6 | 0 | 6 |
| SMIM5 | SH3BGRL2 | 0.863409 | 6 | 0 | 6 |
| SMIM5 | GBP6 | 0.863305 | 4 | 0 | 4 |
| SMIM5 | SNORA68 | 0.861762 | 4 | 0 | 4 |
| SMIM5 | SLURP1 | 0.860235 | 6 | 0 | 6 |
| SMIM5 | UBL3 | 0.856842 | 6 | 0 | 6 |
| SMIM5 | PRSS27 | 0.855983 | 7 | 0 | 7 |
| SMIM5 | SPNS2 | 0.854768 | 5 | 0 | 5 |
| SMIM5 | TGM3 | 0.854079 | 6 | 0 | 6 |
For details and further investigation, click here
