| Full name: Parkinsonism associated deglycase | Alias Symbol: DJ-1|DJ1|GATD2 | ||
| Type: protein-coding gene | Cytoband: 1p36.23 | ||
| Entrez ID: 11315 | HGNC ID: HGNC:16369 | Ensembl Gene: ENSG00000116288 | OMIM ID: 602533 |
| Drug and gene relationship at DGIdb | |||
Expression of PARK7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PARK7 | 11315 | 200006_at | 0.2207 | 0.6084 | |
| GSE20347 | PARK7 | 11315 | 200006_at | 0.2688 | 0.0369 | |
| GSE23400 | PARK7 | 11315 | 200006_at | 0.4399 | 0.0000 | |
| GSE26886 | PARK7 | 11315 | 200006_at | 0.3592 | 0.0454 | |
| GSE29001 | PARK7 | 11315 | 200006_at | 0.4297 | 0.0419 | |
| GSE38129 | PARK7 | 11315 | 200006_at | 0.1980 | 0.1531 | |
| GSE45670 | PARK7 | 11315 | 200006_at | 0.1571 | 0.3416 | |
| GSE53622 | PARK7 | 11315 | 69559 | 0.2195 | 0.0003 | |
| GSE53624 | PARK7 | 11315 | 69559 | 0.5586 | 0.0000 | |
| GSE63941 | PARK7 | 11315 | 200006_at | -0.0848 | 0.8068 | |
| GSE77861 | PARK7 | 11315 | 200006_at | 0.1867 | 0.2054 | |
| GSE97050 | PARK7 | 11315 | A_33_P3231981 | 0.1292 | 0.6810 | |
| SRP007169 | PARK7 | 11315 | RNAseq | 1.1265 | 0.0183 | |
| SRP008496 | PARK7 | 11315 | RNAseq | 0.9288 | 0.0097 | |
| SRP064894 | PARK7 | 11315 | RNAseq | 0.6189 | 0.0249 | |
| SRP133303 | PARK7 | 11315 | RNAseq | 0.5237 | 0.0004 | |
| SRP159526 | PARK7 | 11315 | RNAseq | 0.2730 | 0.1766 | |
| SRP193095 | PARK7 | 11315 | RNAseq | 0.1262 | 0.2844 | |
| SRP219564 | PARK7 | 11315 | RNAseq | 0.1533 | 0.7397 | |
| TCGA | PARK7 | 11315 | RNAseq | -0.0207 | 0.6474 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PARK7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PARK7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PARK7 | 11315 | 1 | 5 | 24 | |
| GSE20123 | PARK7 | 11315 | 1 | 3 | 26 | |
| GSE43470 | PARK7 | 11315 | 6 | 5 | 32 | |
| GSE46452 | PARK7 | 11315 | 7 | 1 | 51 | |
| GSE47630 | PARK7 | 11315 | 8 | 4 | 28 | |
| GSE54993 | PARK7 | 11315 | 3 | 2 | 65 | |
| GSE54994 | PARK7 | 11315 | 14 | 3 | 36 | |
| GSE60625 | PARK7 | 11315 | 0 | 0 | 11 | |
| GSE74703 | PARK7 | 11315 | 5 | 3 | 28 | |
| GSE74704 | PARK7 | 11315 | 1 | 0 | 19 | |
| TCGA | PARK7 | 11315 | 11 | 23 | 62 |
Total number of gains: 57; Total number of losses: 49; Total Number of normals: 382.
Somatic mutations of PARK7:
Generating mutation plots.
Highly correlated genes for PARK7:
Showing top 20/1398 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PARK7 | SBNO1 | 0.851427 | 3 | 0 | 3 |
| PARK7 | TMEM205 | 0.824423 | 3 | 0 | 3 |
| PARK7 | IFT80 | 0.780073 | 3 | 0 | 3 |
| PARK7 | ASH2L | 0.778688 | 4 | 0 | 4 |
| PARK7 | ANKIB1 | 0.77346 | 3 | 0 | 3 |
| PARK7 | RAVER1 | 0.770583 | 3 | 0 | 3 |
| PARK7 | STX10 | 0.758051 | 3 | 0 | 3 |
| PARK7 | NAPB | 0.738016 | 3 | 0 | 3 |
| PARK7 | LMBR1 | 0.732683 | 3 | 0 | 3 |
| PARK7 | NOM1 | 0.730597 | 3 | 0 | 3 |
| PARK7 | PSMC1 | 0.729461 | 3 | 0 | 3 |
| PARK7 | KRTCAP2 | 0.724604 | 3 | 0 | 3 |
| PARK7 | MED26 | 0.724116 | 3 | 0 | 3 |
| PARK7 | RBM26 | 0.722002 | 3 | 0 | 3 |
| PARK7 | DNAJC19 | 0.716131 | 3 | 0 | 3 |
| PARK7 | RAB34 | 0.715045 | 3 | 0 | 3 |
| PARK7 | KDM4A | 0.712705 | 3 | 0 | 3 |
| PARK7 | C16orf46 | 0.711182 | 3 | 0 | 3 |
| PARK7 | PACS1 | 0.710674 | 3 | 0 | 3 |
| PARK7 | EBNA1BP2 | 0.710527 | 3 | 0 | 3 |
For details and further investigation, click here
