| Full name: intraflagellar transport 80 | Alias Symbol: KIAA1374 | ||
| Type: protein-coding gene | Cytoband: 3q25.33 | ||
| Entrez ID: 57560 | HGNC ID: HGNC:29262 | Ensembl Gene: ENSG00000068885 | OMIM ID: 611177 |
| Drug and gene relationship at DGIdb | |||
Expression of IFT80:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFT80 | 57560 | 1558956_s_at | 0.5180 | 0.3880 | |
| GSE26886 | IFT80 | 57560 | 1558956_s_at | 0.2634 | 0.4922 | |
| GSE45670 | IFT80 | 57560 | 1558956_s_at | 0.2352 | 0.2519 | |
| GSE53622 | IFT80 | 57560 | 131029 | 0.4650 | 0.0000 | |
| GSE53624 | IFT80 | 57560 | 131029 | 0.4725 | 0.0000 | |
| GSE63941 | IFT80 | 57560 | 1558956_s_at | -0.1894 | 0.7340 | |
| GSE77861 | IFT80 | 57560 | 1558956_s_at | 0.3341 | 0.3350 | |
| GSE97050 | IFT80 | 57560 | A_23_P316150 | 0.1560 | 0.6074 | |
| SRP007169 | IFT80 | 57560 | RNAseq | 0.6544 | 0.1097 | |
| SRP008496 | IFT80 | 57560 | RNAseq | 0.8533 | 0.0103 | |
| SRP064894 | IFT80 | 57560 | RNAseq | 0.4826 | 0.0459 | |
| SRP133303 | IFT80 | 57560 | RNAseq | 0.7511 | 0.0002 | |
| SRP159526 | IFT80 | 57560 | RNAseq | 1.0565 | 0.0000 | |
| SRP193095 | IFT80 | 57560 | RNAseq | 0.3901 | 0.0034 | |
| SRP219564 | IFT80 | 57560 | RNAseq | 0.3190 | 0.5425 | |
| TCGA | IFT80 | 57560 | RNAseq | 0.2151 | 0.0025 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by IFT80 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFT80:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFT80 | 57560 | 22 | 0 | 8 | |
| GSE20123 | IFT80 | 57560 | 22 | 0 | 8 | |
| GSE43470 | IFT80 | 57560 | 23 | 0 | 20 | |
| GSE46452 | IFT80 | 57560 | 18 | 2 | 39 | |
| GSE47630 | IFT80 | 57560 | 18 | 4 | 18 | |
| GSE54993 | IFT80 | 57560 | 1 | 11 | 58 | |
| GSE54994 | IFT80 | 57560 | 38 | 1 | 14 | |
| GSE60625 | IFT80 | 57560 | 0 | 6 | 5 | |
| GSE74703 | IFT80 | 57560 | 20 | 0 | 16 | |
| GSE74704 | IFT80 | 57560 | 14 | 0 | 6 | |
| TCGA | IFT80 | 57560 | 77 | 0 | 19 |
Total number of gains: 253; Total number of losses: 24; Total Number of normals: 211.
Somatic mutations of IFT80:
Generating mutation plots.
Highly correlated genes for IFT80:
Showing top 20/482 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFT80 | LDLRAP1 | 0.847356 | 3 | 0 | 3 |
| IFT80 | ASXL1 | 0.796937 | 3 | 0 | 3 |
| IFT80 | PRDM15 | 0.789138 | 3 | 0 | 3 |
| IFT80 | PLEKHM2 | 0.787853 | 3 | 0 | 3 |
| IFT80 | PARK7 | 0.780073 | 3 | 0 | 3 |
| IFT80 | PHF6 | 0.772819 | 3 | 0 | 3 |
| IFT80 | RASA2 | 0.770873 | 3 | 0 | 3 |
| IFT80 | MCMBP | 0.761589 | 3 | 0 | 3 |
| IFT80 | ZNF700 | 0.760733 | 3 | 0 | 3 |
| IFT80 | FOXK2 | 0.760511 | 3 | 0 | 3 |
| IFT80 | MIS18A | 0.757189 | 3 | 0 | 3 |
| IFT80 | MRPL42 | 0.750856 | 3 | 0 | 3 |
| IFT80 | MED14 | 0.747115 | 3 | 0 | 3 |
| IFT80 | ASB9 | 0.746351 | 3 | 0 | 3 |
| IFT80 | PCGF3 | 0.74283 | 3 | 0 | 3 |
| IFT80 | ZDHHC6 | 0.742122 | 3 | 0 | 3 |
| IFT80 | E2F8 | 0.741817 | 3 | 0 | 3 |
| IFT80 | MCM3AP | 0.741424 | 3 | 0 | 3 |
| IFT80 | RAB7A | 0.738149 | 3 | 0 | 3 |
| IFT80 | ANKIB1 | 0.732088 | 4 | 0 | 4 |
For details and further investigation, click here
