| Full name: proteasome 26S subunit, ATPase 1 | Alias Symbol: S4|p56 | ||
| Type: protein-coding gene | Cytoband: 14q32.11 | ||
| Entrez ID: 5700 | HGNC ID: HGNC:9547 | Ensembl Gene: ENSG00000100764 | OMIM ID: 602706 |
| Drug and gene relationship at DGIdb | |||
Expression of PSMC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSMC1 | 5700 | 204219_s_at | 0.2021 | 0.5355 | |
| GSE20347 | PSMC1 | 5700 | 204219_s_at | 0.4305 | 0.0008 | |
| GSE23400 | PSMC1 | 5700 | 204219_s_at | 0.4939 | 0.0000 | |
| GSE26886 | PSMC1 | 5700 | 204219_s_at | 0.0033 | 0.9880 | |
| GSE29001 | PSMC1 | 5700 | 204219_s_at | 0.4668 | 0.0189 | |
| GSE38129 | PSMC1 | 5700 | 204219_s_at | 0.4830 | 0.0000 | |
| GSE45670 | PSMC1 | 5700 | 204219_s_at | 0.4685 | 0.0103 | |
| GSE63941 | PSMC1 | 5700 | 204219_s_at | 0.5390 | 0.0482 | |
| GSE77861 | PSMC1 | 5700 | 204219_s_at | 0.6297 | 0.0912 | |
| GSE97050 | PSMC1 | 5700 | A_24_P347488 | 0.1638 | 0.5752 | |
| SRP007169 | PSMC1 | 5700 | RNAseq | -0.0395 | 0.8995 | |
| SRP008496 | PSMC1 | 5700 | RNAseq | -0.0585 | 0.7703 | |
| SRP064894 | PSMC1 | 5700 | RNAseq | 0.5676 | 0.0026 | |
| SRP133303 | PSMC1 | 5700 | RNAseq | 0.6880 | 0.0000 | |
| SRP159526 | PSMC1 | 5700 | RNAseq | 0.6205 | 0.0627 | |
| SRP193095 | PSMC1 | 5700 | RNAseq | 0.3925 | 0.0086 | |
| SRP219564 | PSMC1 | 5700 | RNAseq | 0.4354 | 0.4054 | |
| TCGA | PSMC1 | 5700 | RNAseq | 0.2253 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSMC1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of PSMC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMC1 | 5700 | 9 | 5 | 16 | |
| GSE20123 | PSMC1 | 5700 | 9 | 5 | 16 | |
| GSE43470 | PSMC1 | 5700 | 7 | 3 | 33 | |
| GSE46452 | PSMC1 | 5700 | 16 | 3 | 40 | |
| GSE47630 | PSMC1 | 5700 | 11 | 8 | 21 | |
| GSE54993 | PSMC1 | 5700 | 3 | 8 | 59 | |
| GSE54994 | PSMC1 | 5700 | 18 | 4 | 31 | |
| GSE60625 | PSMC1 | 5700 | 0 | 2 | 9 | |
| GSE74703 | PSMC1 | 5700 | 6 | 3 | 27 | |
| GSE74704 | PSMC1 | 5700 | 4 | 4 | 12 | |
| TCGA | PSMC1 | 5700 | 31 | 21 | 44 |
Total number of gains: 114; Total number of losses: 66; Total Number of normals: 308.
Somatic mutations of PSMC1:
Generating mutation plots.
Highly correlated genes for PSMC1:
Showing top 20/1427 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMC1 | C14orf119 | 0.848365 | 3 | 0 | 3 |
| PSMC1 | BOD1 | 0.815094 | 3 | 0 | 3 |
| PSMC1 | SIVA1 | 0.77851 | 7 | 0 | 7 |
| PSMC1 | SRFBP1 | 0.771839 | 3 | 0 | 3 |
| PSMC1 | MNAT1 | 0.762382 | 10 | 0 | 10 |
| PSMC1 | SLIRP | 0.76104 | 8 | 0 | 8 |
| PSMC1 | L3HYPDH | 0.756159 | 4 | 0 | 4 |
| PSMC1 | FNTA | 0.75352 | 3 | 0 | 3 |
| PSMC1 | TMEM251 | 0.748653 | 9 | 0 | 9 |
| PSMC1 | EIF2S1 | 0.744972 | 11 | 0 | 11 |
| PSMC1 | C1orf43 | 0.743174 | 3 | 0 | 3 |
| PSMC1 | YLPM1 | 0.742589 | 6 | 0 | 6 |
| PSMC1 | RAB13 | 0.74234 | 4 | 0 | 4 |
| PSMC1 | NUS1 | 0.73359 | 4 | 0 | 3 |
| PSMC1 | GLRX5 | 0.730788 | 10 | 0 | 9 |
| PSMC1 | PARK7 | 0.729461 | 3 | 0 | 3 |
| PSMC1 | MED10 | 0.728667 | 4 | 0 | 4 |
| PSMC1 | XAB2 | 0.728507 | 3 | 0 | 3 |
| PSMC1 | RAB12 | 0.726269 | 3 | 0 | 3 |
| PSMC1 | SLC45A4 | 0.724407 | 4 | 0 | 4 |
For details and further investigation, click here
