DNAJC19

 

Full name: DnaJ heat shock protein family (Hsp40) member C19 Alias Symbol: TIMM14|Tim14|Pam18
Type: protein-coding gene Cytoband: 3q26.33
Entrez ID: 131118 HGNC ID: HGNC:30528 Ensembl Gene: ENSG00000205981 OMIM ID: 608977
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of DNAJC19:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DNAJC19 131118 225359_at 0.2680 0.4429
GSE26886 DNAJC19 131118 225358_at -0.1894 0.5303
GSE45670 DNAJC19 131118 225359_at 0.3568 0.1644
GSE53622 DNAJC19 131118 103898 -0.0583 0.6402
GSE53624 DNAJC19 131118 103898 0.1056 0.3586
GSE63941 DNAJC19 131118 225359_at 1.7382 0.0070
GSE77861 DNAJC19 131118 225359_at 0.2723 0.3516
GSE97050 DNAJC19 131118 A_33_P3362869 0.0255 0.9420
SRP007169 DNAJC19 131118 RNAseq 0.8491 0.0747
SRP008496 DNAJC19 131118 RNAseq 0.9669 0.0008
SRP064894 DNAJC19 131118 RNAseq 0.2909 0.1463
SRP133303 DNAJC19 131118 RNAseq 0.7117 0.0114
SRP159526 DNAJC19 131118 RNAseq 1.6635 0.0001
SRP193095 DNAJC19 131118 RNAseq 0.1489 0.2795
SRP219564 DNAJC19 131118 RNAseq -0.1039 0.7335
TCGA DNAJC19 131118 RNAseq 0.0432 0.5928

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by DNAJC19 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of DNAJC19:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DNAJC19 131118 26 0 4
GSE20123 DNAJC19 131118 26 0 4
GSE43470 DNAJC19 131118 24 0 19
GSE46452 DNAJC19 131118 19 1 39
GSE47630 DNAJC19 131118 27 2 11
GSE54993 DNAJC19 131118 1 18 51
GSE54994 DNAJC19 131118 41 0 12
GSE60625 DNAJC19 131118 0 6 5
GSE74703 DNAJC19 131118 20 0 16
GSE74704 DNAJC19 131118 17 0 3
TCGA DNAJC19 131118 77 1 18

Total number of gains: 278; Total number of losses: 28; Total Number of normals: 182.  

 

Somatic mutations of DNAJC19:

 

Generating mutation plots.

 

Highly correlated genes for DNAJC19:

 

Showing top 20/564 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DNAJC19C17orf800.778379303
DNAJC19CWF19L10.775922303
DNAJC19ABI10.775371303
DNAJC19ADO0.76566303
DNAJC19NPRL30.761567303
DNAJC19DHX570.760984303
DNAJC19KLHL110.756873303
DNAJC19BRCA10.756272303
DNAJC19ZNF6890.755892303
DNAJC19AP2M10.753102505
DNAJC19RNF2200.752312303
DNAJC19BTBD20.751713303
DNAJC19BCL7B0.751407303
DNAJC19CRKL0.750772303
DNAJC19FAM86C10.749776303
DNAJC19ACTL6A0.746292606
DNAJC19HNRNPAB0.745373303
DNAJC19CPT1A0.745227303
DNAJC19EMG10.738438404
DNAJC19PPP5C0.736377303

For details and further investigation, click here