| Full name: limb development membrane protein 1 | Alias Symbol: ACHP|FLJ11665|ZRS | ||
| Type: protein-coding gene | Cytoband: 7q36.3 | ||
| Entrez ID: 64327 | HGNC ID: HGNC:13243 | Ensembl Gene: ENSG00000105983 | OMIM ID: 605522 |
| Drug and gene relationship at DGIdb | |||
Expression of LMBR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LMBR1 | 64327 | 224410_s_at | 0.1385 | 0.9030 | |
| GSE26886 | LMBR1 | 64327 | 222505_at | 0.0467 | 0.9065 | |
| GSE45670 | LMBR1 | 64327 | 222505_at | -0.0012 | 0.9962 | |
| GSE53622 | LMBR1 | 64327 | 11764 | 0.6196 | 0.0000 | |
| GSE53624 | LMBR1 | 64327 | 143265 | 0.3896 | 0.0001 | |
| GSE63941 | LMBR1 | 64327 | 224410_s_at | 1.4893 | 0.0059 | |
| GSE77861 | LMBR1 | 64327 | 236357_at | -0.0773 | 0.5204 | |
| GSE97050 | LMBR1 | 64327 | A_33_P3343996 | 0.4450 | 0.1314 | |
| SRP007169 | LMBR1 | 64327 | RNAseq | 1.7137 | 0.0000 | |
| SRP008496 | LMBR1 | 64327 | RNAseq | 1.7427 | 0.0000 | |
| SRP064894 | LMBR1 | 64327 | RNAseq | 0.4139 | 0.0105 | |
| SRP133303 | LMBR1 | 64327 | RNAseq | 0.5769 | 0.0021 | |
| SRP159526 | LMBR1 | 64327 | RNAseq | 0.2550 | 0.4756 | |
| SRP193095 | LMBR1 | 64327 | RNAseq | 0.3154 | 0.0028 | |
| SRP219564 | LMBR1 | 64327 | RNAseq | 0.1450 | 0.6317 | |
| TCGA | LMBR1 | 64327 | RNAseq | -0.1153 | 0.0313 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by LMBR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LMBR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LMBR1 | 64327 | 3 | 3 | 24 | |
| GSE20123 | LMBR1 | 64327 | 2 | 3 | 25 | |
| GSE43470 | LMBR1 | 64327 | 2 | 5 | 36 | |
| GSE46452 | LMBR1 | 64327 | 7 | 2 | 50 | |
| GSE47630 | LMBR1 | 64327 | 6 | 9 | 25 | |
| GSE54993 | LMBR1 | 64327 | 3 | 3 | 64 | |
| GSE54994 | LMBR1 | 64327 | 6 | 8 | 39 | |
| GSE60625 | LMBR1 | 64327 | 0 | 0 | 11 | |
| GSE74703 | LMBR1 | 64327 | 2 | 4 | 30 | |
| GSE74704 | LMBR1 | 64327 | 1 | 3 | 16 | |
| TCGA | LMBR1 | 64327 | 27 | 25 | 44 |
Total number of gains: 59; Total number of losses: 65; Total Number of normals: 364.
Somatic mutations of LMBR1:
Generating mutation plots.
Highly correlated genes for LMBR1:
Showing top 20/339 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LMBR1 | AFTPH | 0.818802 | 3 | 0 | 3 |
| LMBR1 | PRPF38A | 0.792446 | 3 | 0 | 3 |
| LMBR1 | MAT2B | 0.78308 | 3 | 0 | 3 |
| LMBR1 | FAM199X | 0.782607 | 3 | 0 | 3 |
| LMBR1 | PDE6D | 0.778328 | 3 | 0 | 3 |
| LMBR1 | DDX20 | 0.777994 | 3 | 0 | 3 |
| LMBR1 | HMG20A | 0.774408 | 3 | 0 | 3 |
| LMBR1 | IFT46 | 0.76527 | 3 | 0 | 3 |
| LMBR1 | C11orf80 | 0.753674 | 3 | 0 | 3 |
| LMBR1 | LSM4 | 0.734928 | 3 | 0 | 3 |
| LMBR1 | ZFPL1 | 0.733308 | 4 | 0 | 4 |
| LMBR1 | PARK7 | 0.732683 | 3 | 0 | 3 |
| LMBR1 | RRN3 | 0.730332 | 3 | 0 | 3 |
| LMBR1 | DNAJA3 | 0.729779 | 4 | 0 | 4 |
| LMBR1 | POLR2J | 0.726585 | 3 | 0 | 3 |
| LMBR1 | DHODH | 0.724661 | 3 | 0 | 3 |
| LMBR1 | SLC25A40 | 0.724063 | 3 | 0 | 3 |
| LMBR1 | NFKB1 | 0.723796 | 3 | 0 | 3 |
| LMBR1 | RNF34 | 0.721238 | 3 | 0 | 3 |
| LMBR1 | C12orf57 | 0.719122 | 3 | 0 | 3 |
For details and further investigation, click here
