| Full name: protocadherin 8 | Alias Symbol: PAPC|ARCADLIN | ||
| Type: protein-coding gene | Cytoband: 13q14.3 | ||
| Entrez ID: 5100 | HGNC ID: HGNC:8660 | Ensembl Gene: ENSG00000136099 | OMIM ID: 603580 |
| Drug and gene relationship at DGIdb | |||
Expression of PCDH8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCDH8 | 5100 | 206935_at | 0.3800 | 0.6406 | |
| GSE20347 | PCDH8 | 5100 | 206935_at | 0.0156 | 0.7608 | |
| GSE23400 | PCDH8 | 5100 | 206935_at | -0.0073 | 0.6021 | |
| GSE26886 | PCDH8 | 5100 | 206935_at | 1.4028 | 0.0279 | |
| GSE29001 | PCDH8 | 5100 | 206935_at | 0.9491 | 0.2452 | |
| GSE38129 | PCDH8 | 5100 | 206935_at | 0.0117 | 0.8802 | |
| GSE45670 | PCDH8 | 5100 | 206935_at | -0.0090 | 0.9449 | |
| GSE53622 | PCDH8 | 5100 | 109140 | 1.1219 | 0.0000 | |
| GSE53624 | PCDH8 | 5100 | 109140 | 1.4493 | 0.0000 | |
| GSE63941 | PCDH8 | 5100 | 206935_at | 0.3829 | 0.7320 | |
| GSE77861 | PCDH8 | 5100 | 206935_at | 0.0532 | 0.4874 | |
| TCGA | PCDH8 | 5100 | RNAseq | 0.0846 | 0.9376 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by PCDH8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCDH8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCDH8 | 5100 | 2 | 12 | 16 | |
| GSE20123 | PCDH8 | 5100 | 2 | 11 | 17 | |
| GSE43470 | PCDH8 | 5100 | 1 | 12 | 30 | |
| GSE46452 | PCDH8 | 5100 | 0 | 32 | 27 | |
| GSE47630 | PCDH8 | 5100 | 2 | 27 | 11 | |
| GSE54993 | PCDH8 | 5100 | 12 | 2 | 56 | |
| GSE54994 | PCDH8 | 5100 | 1 | 15 | 37 | |
| GSE60625 | PCDH8 | 5100 | 0 | 3 | 8 | |
| GSE74703 | PCDH8 | 5100 | 1 | 10 | 25 | |
| GSE74704 | PCDH8 | 5100 | 0 | 9 | 11 | |
| TCGA | PCDH8 | 5100 | 10 | 35 | 51 |
Total number of gains: 31; Total number of losses: 168; Total Number of normals: 289.
Somatic mutations of PCDH8:
Generating mutation plots.
Highly correlated genes for PCDH8:
Showing top 20/55 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCDH8 | NUP210 | 0.725096 | 3 | 0 | 3 |
| PCDH8 | SALL1 | 0.681543 | 3 | 0 | 3 |
| PCDH8 | PIN4 | 0.668047 | 3 | 0 | 3 |
| PCDH8 | AKAP5 | 0.655487 | 4 | 0 | 3 |
| PCDH8 | UBXN7 | 0.650075 | 3 | 0 | 3 |
| PCDH8 | HNRNPUL1 | 0.645042 | 3 | 0 | 3 |
| PCDH8 | C19orf12 | 0.641112 | 3 | 0 | 3 |
| PCDH8 | EFHD1 | 0.637544 | 4 | 0 | 3 |
| PCDH8 | ADAMTS3 | 0.625234 | 4 | 0 | 3 |
| PCDH8 | OLFM4 | 0.617451 | 8 | 0 | 5 |
| PCDH8 | ST8SIA1 | 0.613372 | 4 | 0 | 3 |
| PCDH8 | TRRAP | 0.607873 | 3 | 0 | 3 |
| PCDH8 | CAPN13 | 0.602316 | 3 | 0 | 3 |
| PCDH8 | MEGF8 | 0.598572 | 4 | 0 | 3 |
| PCDH8 | ZBTB20 | 0.594492 | 3 | 0 | 3 |
| PCDH8 | SULT4A1 | 0.594239 | 4 | 0 | 3 |
| PCDH8 | FOXL2 | 0.592873 | 4 | 0 | 3 |
| PCDH8 | SLC52A1 | 0.589912 | 3 | 0 | 3 |
| PCDH8 | PRSS50 | 0.588795 | 4 | 0 | 3 |
| PCDH8 | CDH12 | 0.582387 | 5 | 0 | 4 |
For details and further investigation, click here
