| Full name: chromosome 19 open reading frame 12 | Alias Symbol: MGC10922|DKFZP762D096|NBIA4|MPAN | ||
| Type: protein-coding gene | Cytoband: 19q12 | ||
| Entrez ID: 83636 | HGNC ID: HGNC:25443 | Ensembl Gene: ENSG00000131943 | OMIM ID: 614297 |
| Drug and gene relationship at DGIdb | |||
Expression of C19orf12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C19orf12 | 83636 | 223983_s_at | 0.2581 | 0.5548 | |
| GSE26886 | C19orf12 | 83636 | 223983_s_at | 0.9912 | 0.0006 | |
| GSE45670 | C19orf12 | 83636 | 223983_s_at | -0.0396 | 0.8663 | |
| GSE53622 | C19orf12 | 83636 | 148852 | 0.0035 | 0.9651 | |
| GSE53624 | C19orf12 | 83636 | 148852 | -0.1357 | 0.0048 | |
| GSE63941 | C19orf12 | 83636 | 223983_s_at | -1.4835 | 0.0048 | |
| GSE77861 | C19orf12 | 83636 | 223983_s_at | 0.1804 | 0.4262 | |
| GSE97050 | C19orf12 | 83636 | A_33_P3300680 | -0.1042 | 0.5754 | |
| SRP007169 | C19orf12 | 83636 | RNAseq | 0.1445 | 0.7542 | |
| SRP008496 | C19orf12 | 83636 | RNAseq | 0.4199 | 0.1950 | |
| SRP064894 | C19orf12 | 83636 | RNAseq | 0.4161 | 0.0024 | |
| SRP133303 | C19orf12 | 83636 | RNAseq | -0.1114 | 0.4858 | |
| SRP159526 | C19orf12 | 83636 | RNAseq | 0.3921 | 0.0420 | |
| SRP193095 | C19orf12 | 83636 | RNAseq | 0.1301 | 0.1668 | |
| SRP219564 | C19orf12 | 83636 | RNAseq | -0.0313 | 0.9222 | |
| TCGA | C19orf12 | 83636 | RNAseq | -0.0068 | 0.9040 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by C19orf12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C19orf12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C19orf12 | 83636 | 6 | 7 | 17 | |
| GSE20123 | C19orf12 | 83636 | 6 | 6 | 18 | |
| GSE43470 | C19orf12 | 83636 | 6 | 6 | 31 | |
| GSE46452 | C19orf12 | 83636 | 47 | 1 | 11 | |
| GSE47630 | C19orf12 | 83636 | 8 | 6 | 26 | |
| GSE54993 | C19orf12 | 83636 | 17 | 3 | 50 | |
| GSE54994 | C19orf12 | 83636 | 7 | 11 | 35 | |
| GSE60625 | C19orf12 | 83636 | 9 | 0 | 2 | |
| GSE74703 | C19orf12 | 83636 | 6 | 4 | 26 | |
| GSE74704 | C19orf12 | 83636 | 5 | 4 | 11 | |
| TCGA | C19orf12 | 83636 | 17 | 14 | 65 |
Total number of gains: 134; Total number of losses: 62; Total Number of normals: 292.
Somatic mutations of C19orf12:
Generating mutation plots.
Highly correlated genes for C19orf12:
Showing top 20/177 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C19orf12 | PDGFRB | 0.698456 | 3 | 0 | 3 |
| C19orf12 | SIMC1 | 0.692967 | 3 | 0 | 3 |
| C19orf12 | PRPF31 | 0.686696 | 3 | 0 | 3 |
| C19orf12 | PARP10 | 0.68039 | 3 | 0 | 3 |
| C19orf12 | SSBP4 | 0.671824 | 4 | 0 | 3 |
| C19orf12 | CD81 | 0.671227 | 3 | 0 | 3 |
| C19orf12 | TPM1 | 0.670832 | 3 | 0 | 3 |
| C19orf12 | ACTG2 | 0.657934 | 3 | 0 | 3 |
| C19orf12 | ZNF805 | 0.654246 | 3 | 0 | 3 |
| C19orf12 | PTGFR | 0.653842 | 3 | 0 | 3 |
| C19orf12 | DGKZ | 0.653348 | 3 | 0 | 3 |
| C19orf12 | ADAMTS6 | 0.651292 | 3 | 0 | 3 |
| C19orf12 | PHF1 | 0.648671 | 4 | 0 | 4 |
| C19orf12 | MLEC | 0.648103 | 3 | 0 | 3 |
| C19orf12 | BRD4 | 0.646006 | 3 | 0 | 3 |
| C19orf12 | AP2A2 | 0.644642 | 3 | 0 | 3 |
| C19orf12 | OSR1 | 0.643227 | 3 | 0 | 3 |
| C19orf12 | CIC | 0.642464 | 4 | 0 | 3 |
| C19orf12 | PCDH8 | 0.641112 | 3 | 0 | 3 |
| C19orf12 | POFUT2 | 0.640188 | 5 | 0 | 3 |
For details and further investigation, click here
