| Full name: transformation/transcription domain associated protein | Alias Symbol: TR-AP|PAF400|Tra1 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 8295 | HGNC ID: HGNC:12347 | Ensembl Gene: ENSG00000196367 | OMIM ID: 603015 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
TRRAP involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05166 | HTLV-I infection |
Expression of TRRAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRRAP | 8295 | 202642_s_at | 0.7040 | 0.1037 | |
| GSE20347 | TRRAP | 8295 | 202642_s_at | 0.6828 | 0.0009 | |
| GSE23400 | TRRAP | 8295 | 202642_s_at | 0.7121 | 0.0000 | |
| GSE26886 | TRRAP | 8295 | 202642_s_at | 1.4905 | 0.0000 | |
| GSE29001 | TRRAP | 8295 | 202642_s_at | 0.5083 | 0.0286 | |
| GSE38129 | TRRAP | 8295 | 202642_s_at | 0.6674 | 0.0000 | |
| GSE45670 | TRRAP | 8295 | 202642_s_at | 0.4886 | 0.0069 | |
| GSE53622 | TRRAP | 8295 | 19331 | 0.5720 | 0.0000 | |
| GSE53624 | TRRAP | 8295 | 19331 | 0.6148 | 0.0000 | |
| GSE63941 | TRRAP | 8295 | 202642_s_at | 0.1036 | 0.8072 | |
| GSE77861 | TRRAP | 8295 | 202642_s_at | 0.6837 | 0.0018 | |
| GSE97050 | TRRAP | 8295 | A_23_P94053 | 0.2994 | 0.2852 | |
| SRP007169 | TRRAP | 8295 | RNAseq | 1.7087 | 0.0008 | |
| SRP008496 | TRRAP | 8295 | RNAseq | 1.7414 | 0.0000 | |
| SRP064894 | TRRAP | 8295 | RNAseq | 0.3255 | 0.1607 | |
| SRP133303 | TRRAP | 8295 | RNAseq | 0.3810 | 0.0016 | |
| SRP159526 | TRRAP | 8295 | RNAseq | 0.2629 | 0.0576 | |
| SRP193095 | TRRAP | 8295 | RNAseq | 0.8336 | 0.0000 | |
| SRP219564 | TRRAP | 8295 | RNAseq | 0.6777 | 0.0654 | |
| TCGA | TRRAP | 8295 | RNAseq | 0.0696 | 0.1863 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by TRRAP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRRAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRRAP | 8295 | 13 | 0 | 17 | |
| GSE20123 | TRRAP | 8295 | 13 | 0 | 17 | |
| GSE43470 | TRRAP | 8295 | 6 | 1 | 36 | |
| GSE46452 | TRRAP | 8295 | 12 | 0 | 47 | |
| GSE47630 | TRRAP | 8295 | 8 | 3 | 29 | |
| GSE54993 | TRRAP | 8295 | 1 | 9 | 60 | |
| GSE54994 | TRRAP | 8295 | 16 | 3 | 34 | |
| GSE60625 | TRRAP | 8295 | 0 | 0 | 11 | |
| GSE74703 | TRRAP | 8295 | 6 | 1 | 29 | |
| GSE74704 | TRRAP | 8295 | 9 | 0 | 11 | |
| TCGA | TRRAP | 8295 | 54 | 4 | 38 |
Total number of gains: 138; Total number of losses: 21; Total Number of normals: 329.
Somatic mutations of TRRAP:
Generating mutation plots.
Highly correlated genes for TRRAP:
Showing top 20/1983 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRRAP | PLEKHA3 | 0.857282 | 3 | 0 | 3 |
| TRRAP | SLC37A3 | 0.835644 | 3 | 0 | 3 |
| TRRAP | ARHGAP24 | 0.815286 | 3 | 0 | 3 |
| TRRAP | TAOK1 | 0.804791 | 3 | 0 | 3 |
| TRRAP | SESTD1 | 0.803494 | 3 | 0 | 3 |
| TRRAP | CASC4 | 0.80262 | 3 | 0 | 3 |
| TRRAP | RILPL1 | 0.793615 | 3 | 0 | 3 |
| TRRAP | TMTC1 | 0.786998 | 3 | 0 | 3 |
| TRRAP | RALGAPB | 0.786449 | 3 | 0 | 3 |
| TRRAP | TSC22D1 | 0.777974 | 3 | 0 | 3 |
| TRRAP | DYRK2 | 0.773423 | 3 | 0 | 3 |
| TRRAP | GPR107 | 0.771702 | 3 | 0 | 3 |
| TRRAP | WDR81 | 0.76947 | 4 | 0 | 3 |
| TRRAP | MRPL38 | 0.760735 | 3 | 0 | 3 |
| TRRAP | ZC3H12C | 0.753148 | 3 | 0 | 3 |
| TRRAP | LRRC58 | 0.746678 | 5 | 0 | 5 |
| TRRAP | SSBP4 | 0.7445 | 5 | 0 | 5 |
| TRRAP | AURKAIP1 | 0.744388 | 3 | 0 | 3 |
| TRRAP | DPYSL2 | 0.743854 | 4 | 0 | 4 |
| TRRAP | KLHL13 | 0.741931 | 4 | 0 | 3 |
For details and further investigation, click here
