| Full name: solute carrier family 52 member 1 | Alias Symbol: FLJ10060|GPCR42|PAR2|hRFT1|RFVT1 | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 55065 | HGNC ID: HGNC:30225 | Ensembl Gene: ENSG00000132517 | OMIM ID: 607883 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC52A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC52A1 | 55065 | 220756_s_at | 0.8663 | 0.1313 | |
| GSE20347 | SLC52A1 | 55065 | 220756_s_at | 0.5261 | 0.0002 | |
| GSE23400 | SLC52A1 | 55065 | 220756_s_at | 0.5142 | 0.0000 | |
| GSE26886 | SLC52A1 | 55065 | 220756_s_at | 1.3179 | 0.0000 | |
| GSE29001 | SLC52A1 | 55065 | 220756_s_at | 0.7205 | 0.0115 | |
| GSE38129 | SLC52A1 | 55065 | 220756_s_at | 0.5562 | 0.0001 | |
| GSE45670 | SLC52A1 | 55065 | 220756_s_at | 0.7471 | 0.0129 | |
| GSE53622 | SLC52A1 | 55065 | 32765 | 0.5372 | 0.0000 | |
| GSE53624 | SLC52A1 | 55065 | 32765 | 0.6478 | 0.0000 | |
| GSE63941 | SLC52A1 | 55065 | 220756_s_at | 0.9402 | 0.1520 | |
| GSE77861 | SLC52A1 | 55065 | 220756_s_at | 0.1381 | 0.6242 | |
| SRP064894 | SLC52A1 | 55065 | RNAseq | 1.8916 | 0.0000 | |
| SRP133303 | SLC52A1 | 55065 | RNAseq | 0.6916 | 0.0039 | |
| SRP159526 | SLC52A1 | 55065 | RNAseq | 1.3356 | 0.0010 | |
| SRP193095 | SLC52A1 | 55065 | RNAseq | 0.6941 | 0.0014 | |
| SRP219564 | SLC52A1 | 55065 | RNAseq | 3.5087 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by SLC52A1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SLC52A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC52A1 | 55065 | 5 | 2 | 23 | |
| GSE20123 | SLC52A1 | 55065 | 5 | 3 | 22 | |
| GSE43470 | SLC52A1 | 55065 | 1 | 6 | 36 | |
| GSE46452 | SLC52A1 | 55065 | 34 | 1 | 24 | |
| GSE47630 | SLC52A1 | 55065 | 7 | 1 | 32 | |
| GSE54993 | SLC52A1 | 55065 | 4 | 3 | 63 | |
| GSE54994 | SLC52A1 | 55065 | 5 | 9 | 39 | |
| GSE60625 | SLC52A1 | 55065 | 4 | 0 | 7 | |
| GSE74703 | SLC52A1 | 55065 | 1 | 3 | 32 | |
| GSE74704 | SLC52A1 | 55065 | 3 | 1 | 16 | |
| TCGA | SLC52A1 | 55065 | 18 | 21 | 57 |
Total number of gains: 87; Total number of losses: 50; Total Number of normals: 351.
Somatic mutations of SLC52A1:
Generating mutation plots.
Highly correlated genes for SLC52A1:
Showing top 20/641 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC52A1 | KRTAP4-1 | 0.78754 | 3 | 0 | 3 |
| SLC52A1 | SIRPB1 | 0.779265 | 3 | 0 | 3 |
| SLC52A1 | BAALC | 0.771828 | 3 | 0 | 3 |
| SLC52A1 | DHX37 | 0.766952 | 3 | 0 | 3 |
| SLC52A1 | TRIM9 | 0.753693 | 3 | 0 | 3 |
| SLC52A1 | LINC00467 | 0.733881 | 3 | 0 | 3 |
| SLC52A1 | NBPF3 | 0.718005 | 3 | 0 | 3 |
| SLC52A1 | TMEM63B | 0.714444 | 4 | 0 | 3 |
| SLC52A1 | TATDN3 | 0.714349 | 3 | 0 | 3 |
| SLC52A1 | KCNQ1OT1 | 0.706768 | 3 | 0 | 3 |
| SLC52A1 | LAGE3 | 0.706127 | 5 | 0 | 5 |
| SLC52A1 | ZEB1-AS1 | 0.704887 | 3 | 0 | 3 |
| SLC52A1 | FBRSL1 | 0.702988 | 5 | 0 | 5 |
| SLC52A1 | GTPBP6 | 0.701806 | 4 | 0 | 4 |
| SLC52A1 | TNFAIP8L1 | 0.696304 | 6 | 0 | 5 |
| SLC52A1 | SLC25A53 | 0.692842 | 4 | 0 | 4 |
| SLC52A1 | USP51 | 0.692241 | 3 | 0 | 3 |
| SLC52A1 | RAVER1 | 0.691537 | 5 | 0 | 5 |
| SLC52A1 | ZNF280C | 0.691137 | 3 | 0 | 3 |
| SLC52A1 | SZT2 | 0.689531 | 4 | 0 | 3 |
For details and further investigation, click here
