| Full name: eyes shut homolog | Alias Symbol: dJ1018A4.2|bA166P24.2|SPAM|bA307F22.3|dJ303F19.1|bA74E24.1 | ||
| Type: protein-coding gene | Cytoband: 6q12 | ||
| Entrez ID: 346007 | HGNC ID: HGNC:21555 | Ensembl Gene: ENSG00000188107 | OMIM ID: 612424 |
| Drug and gene relationship at DGIdb | |||
Expression of EYS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EYS | 346007 | 233996_x_at | 0.0404 | 0.9019 | |
| GSE26886 | EYS | 346007 | 233996_x_at | 0.2806 | 0.0017 | |
| GSE45670 | EYS | 346007 | 233996_x_at | 0.0486 | 0.6836 | |
| GSE53622 | EYS | 346007 | 23724 | -0.1298 | 0.1584 | |
| GSE53624 | EYS | 346007 | 23724 | -0.1791 | 0.0306 | |
| GSE63941 | EYS | 346007 | 233996_x_at | 0.0136 | 0.9377 | |
| GSE77861 | EYS | 346007 | 233996_x_at | 0.0143 | 0.8683 | |
| GSE97050 | EYS | 346007 | A_33_P3276833 | -0.1976 | 0.3843 | |
| SRP133303 | EYS | 346007 | RNAseq | -0.0240 | 0.9152 | |
| SRP159526 | EYS | 346007 | RNAseq | 2.5572 | 0.0258 | |
| TCGA | EYS | 346007 | RNAseq | -0.2416 | 0.2240 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by EYS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EYS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EYS | 346007 | 1 | 4 | 25 | |
| GSE20123 | EYS | 346007 | 1 | 4 | 25 | |
| GSE43470 | EYS | 346007 | 5 | 0 | 38 | |
| GSE46452 | EYS | 346007 | 3 | 10 | 46 | |
| GSE47630 | EYS | 346007 | 8 | 4 | 28 | |
| GSE54993 | EYS | 346007 | 3 | 2 | 65 | |
| GSE54994 | EYS | 346007 | 13 | 2 | 38 | |
| GSE60625 | EYS | 346007 | 0 | 2 | 9 | |
| GSE74703 | EYS | 346007 | 5 | 0 | 31 | |
| GSE74704 | EYS | 346007 | 0 | 3 | 17 | |
| TCGA | EYS | 346007 | 20 | 14 | 62 |
Total number of gains: 59; Total number of losses: 45; Total Number of normals: 384.
Somatic mutations of EYS:
Generating mutation plots.
Highly correlated genes for EYS:
Showing top 20/143 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EYS | INF2 | 0.796367 | 3 | 0 | 3 |
| EYS | BMP8B | 0.788306 | 3 | 0 | 3 |
| EYS | NLRP5 | 0.784238 | 3 | 0 | 3 |
| EYS | OPRD1 | 0.76241 | 3 | 0 | 3 |
| EYS | NPPA | 0.753483 | 3 | 0 | 3 |
| EYS | HOMER1 | 0.752508 | 3 | 0 | 3 |
| EYS | CNGB1 | 0.735457 | 3 | 0 | 3 |
| EYS | CLTCL1 | 0.733378 | 3 | 0 | 3 |
| EYS | LRCH4 | 0.730153 | 4 | 0 | 3 |
| EYS | JAKMIP1 | 0.715649 | 3 | 0 | 3 |
| EYS | PCSK1N | 0.713872 | 3 | 0 | 3 |
| EYS | RHBDD3 | 0.71384 | 3 | 0 | 3 |
| EYS | TMEM68 | 0.707945 | 3 | 0 | 3 |
| EYS | VIPR2 | 0.706611 | 3 | 0 | 3 |
| EYS | GRIN1 | 0.701178 | 3 | 0 | 3 |
| EYS | AMPD2 | 0.695749 | 3 | 0 | 3 |
| EYS | SSTR2 | 0.695625 | 4 | 0 | 4 |
| EYS | CDC42EP2 | 0.694473 | 3 | 0 | 3 |
| EYS | SLC22A31 | 0.694378 | 3 | 0 | 3 |
| EYS | TESC | 0.69426 | 3 | 0 | 3 |
For details and further investigation, click here
