REM2

 

Full name: RRAD and GEM like GTPase 2 Alias Symbol: FLJ38964
Type: protein-coding gene Cytoband: 14q11.2
Entrez ID: 161253 HGNC ID: HGNC:20248 Ensembl Gene: ENSG00000139890 OMIM ID: 616955
Drug and gene relationship at DGIdb

 

Expression of REM2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 REM2 161253 235699_at 0.2619 0.4595
GSE26886 REM2 161253 235699_at 0.2457 0.1033
GSE45670 REM2 161253 235699_at 0.1522 0.1807
GSE53622 REM2 161253 104756 0.0923 0.2628
GSE53624 REM2 161253 104756 0.2078 0.0062
GSE63941 REM2 161253 235699_at 0.7793 0.0030
GSE77861 REM2 161253 235699_at 0.0145 0.8885
GSE97050 REM2 161253 A_33_P3305487 0.1069 0.5608
SRP133303 REM2 161253 RNAseq -0.2435 0.3309
SRP159526 REM2 161253 RNAseq 0.2290 0.6971
SRP219564 REM2 161253 RNAseq 0.4336 0.3750
TCGA REM2 161253 RNAseq 0.5796 0.0197

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by REM2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of REM2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 REM2 161253 9 2 19
GSE20123 REM2 161253 9 2 19
GSE43470 REM2 161253 7 2 34
GSE46452 REM2 161253 17 2 40
GSE47630 REM2 161253 11 10 19
GSE54993 REM2 161253 3 11 56
GSE54994 REM2 161253 18 5 30
GSE60625 REM2 161253 0 2 9
GSE74703 REM2 161253 6 2 28
GSE74704 REM2 161253 4 1 15
TCGA REM2 161253 26 16 54

Total number of gains: 110; Total number of losses: 55; Total Number of normals: 323.  


 

Somatic mutations of REM2:

 

Generating mutation plots.

 

Highly correlated genes for REM2:

 

Showing top 20/110 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
REM2ZMYND150.750512303
REM2LAS1L0.742075303
REM2HK30.734827303
REM2NECAB30.730288303
REM2PRR180.72932303
REM2PHF21A0.72639303
REM2PCSK1N0.726319403
REM2IL27RA0.721483303
REM2KRT90.710568303
REM2NOXA10.702292303
REM2ASMTL0.700728303
REM2GPN20.698801303
REM2SHISA80.695136303
REM2CPAMD80.690531504
REM2CPNE70.689341303
REM2LYG10.68405303
REM2UBXN2B0.677784403
REM2LAMA30.675248303
REM2INF20.672188303
REM2OR7A170.671331303

For details and further investigation, click here