| Full name: small integral membrane protein 2 | Alias Symbol: MGC5590 | ||
| Type: protein-coding gene | Cytoband: 13q14.11 | ||
| Entrez ID: 79024 | HGNC ID: HGNC:28776 | Ensembl Gene: ENSG00000139656 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SMIM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMIM2 | 79024 | 220931_at | -0.0359 | 0.9108 | |
| GSE20347 | SMIM2 | 79024 | 220931_at | -0.1190 | 0.0168 | |
| GSE23400 | SMIM2 | 79024 | 220930_s_at | -0.0282 | 0.4662 | |
| GSE26886 | SMIM2 | 79024 | 220931_at | 0.0599 | 0.5112 | |
| GSE29001 | SMIM2 | 79024 | 220930_s_at | 0.0856 | 0.6033 | |
| GSE38129 | SMIM2 | 79024 | 220931_at | -0.1130 | 0.0159 | |
| GSE45670 | SMIM2 | 79024 | 220931_at | -0.0535 | 0.4472 | |
| GSE63941 | SMIM2 | 79024 | 220931_at | -0.0621 | 0.6790 | |
| GSE77861 | SMIM2 | 79024 | 220931_at | -0.0914 | 0.2924 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of SMIM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMIM2 | 79024 | 0 | 13 | 17 | |
| GSE20123 | SMIM2 | 79024 | 0 | 12 | 18 | |
| GSE43470 | SMIM2 | 79024 | 3 | 13 | 27 | |
| GSE46452 | SMIM2 | 79024 | 0 | 33 | 26 | |
| GSE47630 | SMIM2 | 79024 | 2 | 27 | 11 | |
| GSE54993 | SMIM2 | 79024 | 12 | 2 | 56 | |
| GSE54994 | SMIM2 | 79024 | 1 | 16 | 36 | |
| GSE60625 | SMIM2 | 79024 | 0 | 3 | 8 | |
| GSE74703 | SMIM2 | 79024 | 3 | 10 | 23 | |
| GSE74704 | SMIM2 | 79024 | 0 | 9 | 11 | |
| TCGA | SMIM2 | 79024 | 8 | 39 | 49 |
Total number of gains: 29; Total number of losses: 177; Total Number of normals: 282.
Somatic mutations of SMIM2:
Generating mutation plots.
Highly correlated genes for SMIM2:
Showing top 20/105 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMIM2 | CABP5 | 0.731578 | 3 | 0 | 3 |
| SMIM2 | ATG10 | 0.729478 | 3 | 0 | 3 |
| SMIM2 | BAIAP2L2 | 0.690636 | 3 | 0 | 3 |
| SMIM2 | DUSP15 | 0.667536 | 3 | 0 | 3 |
| SMIM2 | FABP7 | 0.656983 | 3 | 0 | 3 |
| SMIM2 | ZMAT4 | 0.654639 | 3 | 0 | 3 |
| SMIM2 | GNAS-AS1 | 0.646566 | 3 | 0 | 3 |
| SMIM2 | HAPLN1 | 0.645021 | 3 | 0 | 3 |
| SMIM2 | DPYS | 0.644664 | 3 | 0 | 3 |
| SMIM2 | FCAR | 0.643441 | 3 | 0 | 3 |
| SMIM2 | MEP1B | 0.635467 | 3 | 0 | 3 |
| SMIM2 | KCNF1 | 0.634651 | 3 | 0 | 3 |
| SMIM2 | CASZ1 | 0.634502 | 3 | 0 | 3 |
| SMIM2 | PECR | 0.63362 | 3 | 0 | 3 |
| SMIM2 | SYT13 | 0.628028 | 3 | 0 | 3 |
| SMIM2 | AFP | 0.627621 | 5 | 0 | 5 |
| SMIM2 | ZNF536 | 0.627262 | 3 | 0 | 3 |
| SMIM2 | KRTAP4-7 | 0.62547 | 4 | 0 | 3 |
| SMIM2 | KALRN | 0.616847 | 3 | 0 | 3 |
| SMIM2 | GCM2 | 0.616821 | 4 | 0 | 4 |
For details and further investigation, click here
