| Full name: three prime repair exonuclease 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 11219 | HGNC ID: HGNC:12270 | Ensembl Gene: ENSG00000183479 | OMIM ID: 300370 |
| Drug and gene relationship at DGIdb | |||
Expression of TREX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | TREX2 | 11219 | 109889 | -0.8100 | 0.0012 | |
| GSE53624 | TREX2 | 11219 | 109889 | -1.6946 | 0.0000 | |
| GSE97050 | TREX2 | 11219 | A_33_P3383856 | 0.0715 | 0.8288 | |
| SRP007169 | TREX2 | 11219 | RNAseq | -7.4648 | 0.0000 | |
| SRP064894 | TREX2 | 11219 | RNAseq | -0.9161 | 0.0380 | |
| SRP133303 | TREX2 | 11219 | RNAseq | -0.8516 | 0.0365 | |
| SRP159526 | TREX2 | 11219 | RNAseq | -0.1586 | 0.8073 | |
| SRP219564 | TREX2 | 11219 | RNAseq | -0.3742 | 0.5965 | |
| TCGA | TREX2 | 11219 | RNAseq | 0.5488 | 0.1084 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TREX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TREX2:
No record found for this gene.
Somatic mutations of TREX2:
Generating mutation plots.
Highly correlated genes for TREX2:
Showing top 20/160 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TREX2 | RDH12 | 0.722691 | 3 | 0 | 3 |
| TREX2 | MPZL3 | 0.71244 | 3 | 0 | 3 |
| TREX2 | S100A12 | 0.695476 | 3 | 0 | 3 |
| TREX2 | CDA | 0.693492 | 3 | 0 | 3 |
| TREX2 | MREG | 0.686128 | 3 | 0 | 3 |
| TREX2 | PXMP2 | 0.684349 | 3 | 0 | 3 |
| TREX2 | ARG1 | 0.680848 | 3 | 0 | 3 |
| TREX2 | RABGGTA | 0.67996 | 3 | 0 | 3 |
| TREX2 | ALDH3B2 | 0.679528 | 3 | 0 | 3 |
| TREX2 | ASPG | 0.677396 | 3 | 0 | 3 |
| TREX2 | CST6 | 0.676484 | 3 | 0 | 3 |
| TREX2 | TMEM45B | 0.676279 | 3 | 0 | 3 |
| TREX2 | CPA4 | 0.676134 | 3 | 0 | 3 |
| TREX2 | ATG9B | 0.675146 | 3 | 0 | 3 |
| TREX2 | PGM2 | 0.672693 | 3 | 0 | 3 |
| TREX2 | KRT80 | 0.672573 | 3 | 0 | 3 |
| TREX2 | KCTD11 | 0.670561 | 3 | 0 | 3 |
| TREX2 | ELOVL1 | 0.668108 | 3 | 0 | 3 |
| TREX2 | ANKRD31 | 0.666495 | 3 | 0 | 3 |
| TREX2 | RAB25 | 0.66279 | 3 | 0 | 3 |
For details and further investigation, click here
