| Full name: mitochondrial calcium uptake 1 | Alias Symbol: CALC|EFHA3|FLJ12684 | ||
| Type: protein-coding gene | Cytoband: 10q22.1 | ||
| Entrez ID: 10367 | HGNC ID: HGNC:1530 | Ensembl Gene: ENSG00000107745 | OMIM ID: 605084 |
| Drug and gene relationship at DGIdb | |||
Expression of MICU1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MICU1 | 10367 | 216903_s_at | 0.2670 | 0.5186 | |
| GSE20347 | MICU1 | 10367 | 216903_s_at | 0.2879 | 0.0057 | |
| GSE23400 | MICU1 | 10367 | 216903_s_at | -0.0530 | 0.3183 | |
| GSE26886 | MICU1 | 10367 | 216903_s_at | -0.2106 | 0.0767 | |
| GSE29001 | MICU1 | 10367 | 216903_s_at | -0.1169 | 0.5267 | |
| GSE38129 | MICU1 | 10367 | 216903_s_at | 0.2104 | 0.1431 | |
| GSE45670 | MICU1 | 10367 | 216903_s_at | 0.0033 | 0.9803 | |
| GSE53622 | MICU1 | 10367 | 114597 | 0.1135 | 0.1187 | |
| GSE53624 | MICU1 | 10367 | 114597 | 0.4346 | 0.0000 | |
| GSE63941 | MICU1 | 10367 | 216903_s_at | 0.0075 | 0.9885 | |
| GSE77861 | MICU1 | 10367 | 216903_s_at | 0.1093 | 0.4394 | |
| GSE97050 | MICU1 | 10367 | A_23_P46907 | 0.1411 | 0.5329 | |
| SRP007169 | MICU1 | 10367 | RNAseq | -0.5647 | 0.2308 | |
| SRP008496 | MICU1 | 10367 | RNAseq | -0.3229 | 0.2389 | |
| SRP064894 | MICU1 | 10367 | RNAseq | 0.0522 | 0.7217 | |
| SRP133303 | MICU1 | 10367 | RNAseq | 0.5272 | 0.0016 | |
| SRP159526 | MICU1 | 10367 | RNAseq | 0.0826 | 0.7268 | |
| SRP193095 | MICU1 | 10367 | RNAseq | -0.2193 | 0.1946 | |
| SRP219564 | MICU1 | 10367 | RNAseq | -0.0327 | 0.9257 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MICU1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MICU1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MICU1 | 10367 | 4 | 4 | 22 | |
| GSE20123 | MICU1 | 10367 | 4 | 3 | 23 | |
| GSE43470 | MICU1 | 10367 | 1 | 8 | 34 | |
| GSE46452 | MICU1 | 10367 | 0 | 11 | 48 | |
| GSE47630 | MICU1 | 10367 | 2 | 14 | 24 | |
| GSE54993 | MICU1 | 10367 | 7 | 0 | 63 | |
| GSE54994 | MICU1 | 10367 | 2 | 11 | 40 | |
| GSE60625 | MICU1 | 10367 | 0 | 0 | 11 | |
| GSE74703 | MICU1 | 10367 | 1 | 5 | 30 | |
| GSE74704 | MICU1 | 10367 | 2 | 1 | 17 | |
| TCGA | MICU1 | 10367 | 11 | 23 | 62 |
Total number of gains: 34; Total number of losses: 80; Total Number of normals: 374.
Somatic mutations of MICU1:
Generating mutation plots.
Highly correlated genes for MICU1:
Showing top 20/348 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MICU1 | USP13 | 0.773312 | 3 | 0 | 3 |
| MICU1 | KLHL21 | 0.763108 | 3 | 0 | 3 |
| MICU1 | SWT1 | 0.760904 | 3 | 0 | 3 |
| MICU1 | PELI2 | 0.742207 | 3 | 0 | 3 |
| MICU1 | PEG10 | 0.719265 | 4 | 0 | 4 |
| MICU1 | FAM102B | 0.708036 | 4 | 0 | 3 |
| MICU1 | UBB | 0.707684 | 5 | 0 | 5 |
| MICU1 | RAVER1 | 0.706293 | 3 | 0 | 3 |
| MICU1 | EP400 | 0.702387 | 3 | 0 | 3 |
| MICU1 | LIG3 | 0.697977 | 4 | 0 | 3 |
| MICU1 | TBCB | 0.697652 | 4 | 0 | 4 |
| MICU1 | CXCL16 | 0.697348 | 3 | 0 | 3 |
| MICU1 | PHC2 | 0.697325 | 6 | 0 | 6 |
| MICU1 | HNRNPA1 | 0.695744 | 3 | 0 | 3 |
| MICU1 | FAM160B1 | 0.695357 | 3 | 0 | 3 |
| MICU1 | SENP2 | 0.695145 | 3 | 0 | 3 |
| MICU1 | MAT2B | 0.692418 | 3 | 0 | 3 |
| MICU1 | NEURL1B | 0.690596 | 3 | 0 | 3 |
| MICU1 | DNMBP | 0.68594 | 3 | 0 | 3 |
| MICU1 | EFCAB7 | 0.683932 | 4 | 0 | 3 |
For details and further investigation, click here
