| Full name: zinc finger protein 827 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q31.21-q31.22 | ||
| Entrez ID: 152485 | HGNC ID: HGNC:27193 | Ensembl Gene: ENSG00000151612 | OMIM ID: 617962 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZNF827:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF827 | 152485 | 228046_at | 0.4736 | 0.3793 | |
| GSE26886 | ZNF827 | 152485 | 243618_s_at | 2.2380 | 0.0000 | |
| GSE45670 | ZNF827 | 152485 | 243618_s_at | 0.9569 | 0.0001 | |
| GSE53622 | ZNF827 | 152485 | 56035 | 0.9747 | 0.0000 | |
| GSE53624 | ZNF827 | 152485 | 9081 | 0.6738 | 0.0000 | |
| GSE63941 | ZNF827 | 152485 | 243618_s_at | -0.3625 | 0.6209 | |
| GSE77861 | ZNF827 | 152485 | 243618_s_at | 0.8813 | 0.0499 | |
| GSE97050 | ZNF827 | 152485 | A_23_P320290 | 0.3582 | 0.4141 | |
| SRP007169 | ZNF827 | 152485 | RNAseq | 2.5093 | 0.0000 | |
| SRP008496 | ZNF827 | 152485 | RNAseq | 2.3482 | 0.0000 | |
| SRP064894 | ZNF827 | 152485 | RNAseq | 0.8088 | 0.0000 | |
| SRP133303 | ZNF827 | 152485 | RNAseq | 1.1199 | 0.0000 | |
| SRP159526 | ZNF827 | 152485 | RNAseq | 0.2968 | 0.3539 | |
| SRP193095 | ZNF827 | 152485 | RNAseq | 0.9899 | 0.0000 | |
| SRP219564 | ZNF827 | 152485 | RNAseq | 0.2185 | 0.6206 | |
| TCGA | ZNF827 | 152485 | RNAseq | 0.0749 | 0.4594 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by ZNF827 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF827:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF827 | 152485 | 0 | 12 | 18 | |
| GSE20123 | ZNF827 | 152485 | 0 | 12 | 18 | |
| GSE43470 | ZNF827 | 152485 | 0 | 13 | 30 | |
| GSE46452 | ZNF827 | 152485 | 1 | 36 | 22 | |
| GSE47630 | ZNF827 | 152485 | 0 | 22 | 18 | |
| GSE54993 | ZNF827 | 152485 | 10 | 0 | 60 | |
| GSE54994 | ZNF827 | 152485 | 2 | 11 | 40 | |
| GSE60625 | ZNF827 | 152485 | 0 | 1 | 10 | |
| GSE74703 | ZNF827 | 152485 | 0 | 11 | 25 | |
| GSE74704 | ZNF827 | 152485 | 0 | 7 | 13 | |
| TCGA | ZNF827 | 152485 | 12 | 32 | 52 |
Total number of gains: 25; Total number of losses: 157; Total Number of normals: 306.
Somatic mutations of ZNF827:
Generating mutation plots.
Highly correlated genes for ZNF827:
Showing top 20/1220 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF827 | SERPINF2 | 0.793918 | 3 | 0 | 3 |
| ZNF827 | SGCE | 0.792451 | 3 | 0 | 3 |
| ZNF827 | PRTFDC1 | 0.784865 | 6 | 0 | 6 |
| ZNF827 | KLF10 | 0.78466 | 3 | 0 | 3 |
| ZNF827 | MXRA7 | 0.776124 | 3 | 0 | 3 |
| ZNF827 | ZNF358 | 0.775734 | 3 | 0 | 3 |
| ZNF827 | ZBED1 | 0.773826 | 3 | 0 | 3 |
| ZNF827 | SDR39U1 | 0.765348 | 3 | 0 | 3 |
| ZNF827 | LRP4 | 0.757485 | 3 | 0 | 3 |
| ZNF827 | LINC00674 | 0.754303 | 3 | 0 | 3 |
| ZNF827 | CHIC1 | 0.753214 | 4 | 0 | 3 |
| ZNF827 | PATZ1 | 0.749941 | 4 | 0 | 4 |
| ZNF827 | CDC42EP4 | 0.746355 | 4 | 0 | 4 |
| ZNF827 | CUX1 | 0.745463 | 6 | 0 | 6 |
| ZNF827 | AP3D1 | 0.742333 | 4 | 0 | 4 |
| ZNF827 | KCNMB4 | 0.736981 | 3 | 0 | 3 |
| ZNF827 | ARMC9 | 0.735186 | 3 | 0 | 3 |
| ZNF827 | EBAG9 | 0.734929 | 4 | 0 | 4 |
| ZNF827 | BMP2 | 0.73411 | 3 | 0 | 3 |
| ZNF827 | IL17RD | 0.734078 | 4 | 0 | 4 |
For details and further investigation, click here
