| Full name: fasciculation and elongation protein zeta 1 | Alias Symbol: UNC-76 | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 9638 | HGNC ID: HGNC:3659 | Ensembl Gene: ENSG00000149557 | OMIM ID: 604825 |
| Drug and gene relationship at DGIdb | |||
Expression of FEZ1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FEZ1 | 9638 | 203562_at | 0.1825 | 0.9088 | |
| GSE20347 | FEZ1 | 9638 | 203562_at | 1.0758 | 0.0003 | |
| GSE23400 | FEZ1 | 9638 | 203562_at | 0.4415 | 0.0028 | |
| GSE26886 | FEZ1 | 9638 | 203562_at | 3.4421 | 0.0000 | |
| GSE29001 | FEZ1 | 9638 | 203562_at | 1.1880 | 0.0006 | |
| GSE38129 | FEZ1 | 9638 | 203562_at | 0.2799 | 0.5562 | |
| GSE45670 | FEZ1 | 9638 | 203562_at | -0.1185 | 0.8765 | |
| GSE53622 | FEZ1 | 9638 | 8251 | 0.5278 | 0.0064 | |
| GSE53624 | FEZ1 | 9638 | 8251 | 0.8605 | 0.0000 | |
| GSE63941 | FEZ1 | 9638 | 203562_at | -3.3231 | 0.0463 | |
| GSE77861 | FEZ1 | 9638 | 203562_at | 2.3440 | 0.0098 | |
| GSE97050 | FEZ1 | 9638 | A_23_P202881 | -0.0131 | 0.9639 | |
| SRP007169 | FEZ1 | 9638 | RNAseq | 5.2634 | 0.0019 | |
| SRP008496 | FEZ1 | 9638 | RNAseq | 5.0207 | 0.0000 | |
| SRP064894 | FEZ1 | 9638 | RNAseq | 0.8275 | 0.0010 | |
| SRP133303 | FEZ1 | 9638 | RNAseq | 0.5821 | 0.0003 | |
| SRP159526 | FEZ1 | 9638 | RNAseq | 1.0272 | 0.0171 | |
| SRP193095 | FEZ1 | 9638 | RNAseq | 1.5424 | 0.0000 | |
| SRP219564 | FEZ1 | 9638 | RNAseq | -0.2030 | 0.8052 | |
| TCGA | FEZ1 | 9638 | RNAseq | 0.2469 | 0.0877 |
Upregulated datasets: 8; Downregulated datasets: 1.
Survival by FEZ1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FEZ1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FEZ1 | 9638 | 0 | 13 | 17 | |
| GSE20123 | FEZ1 | 9638 | 0 | 13 | 17 | |
| GSE43470 | FEZ1 | 9638 | 2 | 7 | 34 | |
| GSE46452 | FEZ1 | 9638 | 3 | 26 | 30 | |
| GSE47630 | FEZ1 | 9638 | 2 | 19 | 19 | |
| GSE54993 | FEZ1 | 9638 | 10 | 0 | 60 | |
| GSE54994 | FEZ1 | 9638 | 5 | 19 | 29 | |
| GSE60625 | FEZ1 | 9638 | 0 | 3 | 8 | |
| GSE74703 | FEZ1 | 9638 | 1 | 5 | 30 | |
| GSE74704 | FEZ1 | 9638 | 0 | 9 | 11 | |
| TCGA | FEZ1 | 9638 | 6 | 50 | 40 |
Total number of gains: 29; Total number of losses: 164; Total Number of normals: 295.
Somatic mutations of FEZ1:
Generating mutation plots.
Highly correlated genes for FEZ1:
Showing top 20/1501 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FEZ1 | GAS2L1 | 0.80092 | 3 | 0 | 3 |
| FEZ1 | PPP1R35 | 0.795828 | 3 | 0 | 3 |
| FEZ1 | ECSIT | 0.791845 | 3 | 0 | 3 |
| FEZ1 | TRMT6 | 0.783577 | 3 | 0 | 3 |
| FEZ1 | DZIP1L | 0.758866 | 3 | 0 | 3 |
| FEZ1 | PHIP | 0.749053 | 3 | 0 | 3 |
| FEZ1 | CTU2 | 0.739928 | 3 | 0 | 3 |
| FEZ1 | METTL23 | 0.735468 | 4 | 0 | 4 |
| FEZ1 | EMD | 0.735197 | 3 | 0 | 3 |
| FEZ1 | NPRL3 | 0.727844 | 3 | 0 | 3 |
| FEZ1 | MCM8 | 0.72327 | 3 | 0 | 3 |
| FEZ1 | SEMA3C | 0.719262 | 11 | 0 | 11 |
| FEZ1 | KLHL31 | 0.719203 | 3 | 0 | 3 |
| FEZ1 | EGFLAM | 0.717643 | 4 | 0 | 3 |
| FEZ1 | PSMB4 | 0.717531 | 5 | 0 | 5 |
| FEZ1 | CEP95 | 0.716424 | 3 | 0 | 3 |
| FEZ1 | PET117 | 0.716214 | 3 | 0 | 3 |
| FEZ1 | BRAT1 | 0.714763 | 4 | 0 | 3 |
| FEZ1 | TRRAP | 0.712418 | 3 | 0 | 3 |
| FEZ1 | ZC3HC1 | 0.71152 | 3 | 0 | 3 |
For details and further investigation, click here
