| Full name: SP100 nuclear antigen | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q37.1 | ||
| Entrez ID: 6672 | HGNC ID: HGNC:11206 | Ensembl Gene: ENSG00000067066 | OMIM ID: 604585 |
| Drug and gene relationship at DGIdb | |||
Expression of SP100:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SP100 | 6672 | 202864_s_at | -0.0035 | 0.9970 | |
| GSE20347 | SP100 | 6672 | 202864_s_at | 0.2725 | 0.1930 | |
| GSE23400 | SP100 | 6672 | 202863_at | 0.6722 | 0.0000 | |
| GSE26886 | SP100 | 6672 | 202863_at | 2.0795 | 0.0000 | |
| GSE29001 | SP100 | 6672 | 202863_at | 1.1438 | 0.0006 | |
| GSE38129 | SP100 | 6672 | 202864_s_at | 0.0728 | 0.7022 | |
| GSE45670 | SP100 | 6672 | 202863_at | 0.3149 | 0.2520 | |
| GSE53622 | SP100 | 6672 | 33845 | 0.3843 | 0.0002 | |
| GSE53624 | SP100 | 6672 | 33845 | 0.6185 | 0.0000 | |
| GSE63941 | SP100 | 6672 | 202864_s_at | -0.9576 | 0.1698 | |
| GSE77861 | SP100 | 6672 | 202864_s_at | 0.5341 | 0.0422 | |
| GSE97050 | SP100 | 6672 | A_23_P349928 | -0.1164 | 0.5982 | |
| SRP007169 | SP100 | 6672 | RNAseq | 1.4256 | 0.0039 | |
| SRP008496 | SP100 | 6672 | RNAseq | 1.3138 | 0.0000 | |
| SRP064894 | SP100 | 6672 | RNAseq | 0.9825 | 0.0000 | |
| SRP133303 | SP100 | 6672 | RNAseq | 0.3617 | 0.0161 | |
| SRP159526 | SP100 | 6672 | RNAseq | -0.2787 | 0.4594 | |
| SRP193095 | SP100 | 6672 | RNAseq | 0.5935 | 0.0004 | |
| SRP219564 | SP100 | 6672 | RNAseq | 0.5668 | 0.1176 | |
| TCGA | SP100 | 6672 | RNAseq | 0.0099 | 0.8764 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by SP100 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SP100:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SP100 | 6672 | 1 | 13 | 16 | |
| GSE20123 | SP100 | 6672 | 1 | 13 | 16 | |
| GSE43470 | SP100 | 6672 | 2 | 8 | 33 | |
| GSE46452 | SP100 | 6672 | 0 | 5 | 54 | |
| GSE47630 | SP100 | 6672 | 4 | 5 | 31 | |
| GSE54993 | SP100 | 6672 | 2 | 2 | 66 | |
| GSE54994 | SP100 | 6672 | 6 | 11 | 36 | |
| GSE60625 | SP100 | 6672 | 0 | 3 | 8 | |
| GSE74703 | SP100 | 6672 | 2 | 6 | 28 | |
| GSE74704 | SP100 | 6672 | 1 | 6 | 13 | |
| TCGA | SP100 | 6672 | 13 | 27 | 56 |
Total number of gains: 32; Total number of losses: 99; Total Number of normals: 357.
Somatic mutations of SP100:
Generating mutation plots.
Highly correlated genes for SP100:
Showing top 20/870 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SP100 | PHIP | 0.794521 | 3 | 0 | 3 |
| SP100 | ZNF503 | 0.788805 | 3 | 0 | 3 |
| SP100 | IDS | 0.770811 | 3 | 0 | 3 |
| SP100 | IQCB1 | 0.770703 | 3 | 0 | 3 |
| SP100 | NCKIPSD | 0.767502 | 3 | 0 | 3 |
| SP100 | FAM126A | 0.76514 | 3 | 0 | 3 |
| SP100 | RIOK1 | 0.764164 | 3 | 0 | 3 |
| SP100 | SAG | 0.7568 | 3 | 0 | 3 |
| SP100 | KIAA1324L | 0.747985 | 3 | 0 | 3 |
| SP100 | ATR | 0.747072 | 5 | 0 | 5 |
| SP100 | ATP9A | 0.741001 | 3 | 0 | 3 |
| SP100 | MEA1 | 0.740342 | 3 | 0 | 3 |
| SP100 | ASB2 | 0.740311 | 4 | 0 | 4 |
| SP100 | SP110 | 0.73958 | 13 | 0 | 11 |
| SP100 | IRF2BP2 | 0.735093 | 4 | 0 | 4 |
| SP100 | DDX60 | 0.732686 | 13 | 0 | 12 |
| SP100 | CRTC2 | 0.72865 | 3 | 0 | 3 |
| SP100 | MYH3 | 0.724632 | 3 | 0 | 3 |
| SP100 | IFIT1 | 0.724312 | 13 | 0 | 12 |
| SP100 | ERGIC2 | 0.719402 | 3 | 0 | 3 |
For details and further investigation, click here
