| Full name: Rho GTPase activating protein 24 | Alias Symbol: DKFZP564B1162|FLJ33877|FilGAP | ||
| Type: protein-coding gene | Cytoband: 4q21.23-q21.3 | ||
| Entrez ID: 83478 | HGNC ID: HGNC:25361 | Ensembl Gene: ENSG00000138639 | OMIM ID: 610586 |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGAP24:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGAP24 | 83478 | 223422_s_at | -0.0745 | 0.9063 | |
| GSE20347 | ARHGAP24 | 83478 | 221030_s_at | 0.1851 | 0.1080 | |
| GSE23400 | ARHGAP24 | 83478 | 221030_s_at | -0.0370 | 0.3895 | |
| GSE26886 | ARHGAP24 | 83478 | 223422_s_at | 1.6710 | 0.0000 | |
| GSE29001 | ARHGAP24 | 83478 | 221030_s_at | 0.0706 | 0.8048 | |
| GSE38129 | ARHGAP24 | 83478 | 221030_s_at | -0.2130 | 0.2346 | |
| GSE45670 | ARHGAP24 | 83478 | 223422_s_at | -0.2634 | 0.4493 | |
| GSE53622 | ARHGAP24 | 83478 | 71938 | -0.4040 | 0.0087 | |
| GSE53624 | ARHGAP24 | 83478 | 71938 | -0.4410 | 0.0080 | |
| GSE63941 | ARHGAP24 | 83478 | 223422_s_at | -3.5299 | 0.0004 | |
| GSE77861 | ARHGAP24 | 83478 | 223422_s_at | 0.7174 | 0.0522 | |
| GSE97050 | ARHGAP24 | 83478 | A_33_P3236030 | 0.3558 | 0.1556 | |
| SRP007169 | ARHGAP24 | 83478 | RNAseq | 2.4057 | 0.0001 | |
| SRP008496 | ARHGAP24 | 83478 | RNAseq | 2.7493 | 0.0000 | |
| SRP064894 | ARHGAP24 | 83478 | RNAseq | 0.5148 | 0.0791 | |
| SRP133303 | ARHGAP24 | 83478 | RNAseq | 0.1752 | 0.3485 | |
| SRP159526 | ARHGAP24 | 83478 | RNAseq | 0.4726 | 0.2812 | |
| SRP193095 | ARHGAP24 | 83478 | RNAseq | 0.6032 | 0.0357 | |
| SRP219564 | ARHGAP24 | 83478 | RNAseq | -0.0507 | 0.9399 | |
| TCGA | ARHGAP24 | 83478 | RNAseq | -0.6398 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by ARHGAP24 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGAP24:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGAP24 | 83478 | 3 | 11 | 16 | |
| GSE20123 | ARHGAP24 | 83478 | 3 | 11 | 16 | |
| GSE43470 | ARHGAP24 | 83478 | 0 | 13 | 30 | |
| GSE46452 | ARHGAP24 | 83478 | 1 | 36 | 22 | |
| GSE47630 | ARHGAP24 | 83478 | 0 | 20 | 20 | |
| GSE54993 | ARHGAP24 | 83478 | 8 | 0 | 62 | |
| GSE54994 | ARHGAP24 | 83478 | 1 | 9 | 43 | |
| GSE60625 | ARHGAP24 | 83478 | 0 | 0 | 11 | |
| GSE74703 | ARHGAP24 | 83478 | 0 | 11 | 25 | |
| GSE74704 | ARHGAP24 | 83478 | 2 | 6 | 12 | |
| TCGA | ARHGAP24 | 83478 | 12 | 38 | 46 |
Total number of gains: 30; Total number of losses: 155; Total Number of normals: 303.
Somatic mutations of ARHGAP24:
Generating mutation plots.
Highly correlated genes for ARHGAP24:
Showing top 20/1077 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGAP24 | TRRAP | 0.815286 | 3 | 0 | 3 |
| ARHGAP24 | PHIP | 0.804102 | 3 | 0 | 3 |
| ARHGAP24 | SDR39U1 | 0.802009 | 3 | 0 | 3 |
| ARHGAP24 | ANPEP | 0.800473 | 4 | 0 | 4 |
| ARHGAP24 | PLXNA1 | 0.784601 | 3 | 0 | 3 |
| ARHGAP24 | LSM10 | 0.783572 | 3 | 0 | 3 |
| ARHGAP24 | FKBP7 | 0.781873 | 4 | 0 | 4 |
| ARHGAP24 | MIEN1 | 0.777095 | 3 | 0 | 3 |
| ARHGAP24 | SLC25A32 | 0.768729 | 3 | 0 | 3 |
| ARHGAP24 | ING1 | 0.766207 | 3 | 0 | 3 |
| ARHGAP24 | GPR107 | 0.763849 | 3 | 0 | 3 |
| ARHGAP24 | MINPP1 | 0.763844 | 4 | 0 | 4 |
| ARHGAP24 | HLTF | 0.753057 | 3 | 0 | 3 |
| ARHGAP24 | TTC8 | 0.751047 | 3 | 0 | 3 |
| ARHGAP24 | CEP120 | 0.750356 | 5 | 0 | 5 |
| ARHGAP24 | DPY19L4 | 0.749667 | 3 | 0 | 3 |
| ARHGAP24 | SLC24A1 | 0.744034 | 3 | 0 | 3 |
| ARHGAP24 | GLIPR1 | 0.742892 | 3 | 0 | 3 |
| ARHGAP24 | MET | 0.740503 | 3 | 0 | 3 |
| ARHGAP24 | GLIS3 | 0.726336 | 3 | 0 | 3 |
For details and further investigation, click here
