| Full name: putative homeodomain transcription factor 2 | Alias Symbol: DKFZp434D166 | ||
| Type: protein-coding gene | Cytoband: 7q11.23-q21.11 | ||
| Entrez ID: 57157 | HGNC ID: HGNC:13411 | Ensembl Gene: ENSG00000006576 | OMIM ID: 616785 |
| Drug and gene relationship at DGIdb | |||
Expression of PHTF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHTF2 | 57157 | 209780_at | 0.5155 | 0.1704 | |
| GSE20347 | PHTF2 | 57157 | 209780_at | 0.7545 | 0.0003 | |
| GSE23400 | PHTF2 | 57157 | 209780_at | 0.5958 | 0.0000 | |
| GSE26886 | PHTF2 | 57157 | 209780_at | 0.9313 | 0.0002 | |
| GSE29001 | PHTF2 | 57157 | 209780_at | 0.4555 | 0.2273 | |
| GSE38129 | PHTF2 | 57157 | 209780_at | 0.7276 | 0.0000 | |
| GSE45670 | PHTF2 | 57157 | 209780_at | 0.1369 | 0.3981 | |
| GSE53622 | PHTF2 | 57157 | 70367 | 0.5368 | 0.0000 | |
| GSE53624 | PHTF2 | 57157 | 70367 | 0.5191 | 0.0000 | |
| GSE63941 | PHTF2 | 57157 | 209780_at | -0.8372 | 0.1693 | |
| GSE77861 | PHTF2 | 57157 | 209780_at | 0.3791 | 0.0671 | |
| GSE97050 | PHTF2 | 57157 | A_24_P175176 | 0.4583 | 0.1678 | |
| SRP007169 | PHTF2 | 57157 | RNAseq | 1.1540 | 0.0020 | |
| SRP008496 | PHTF2 | 57157 | RNAseq | 1.4242 | 0.0000 | |
| SRP064894 | PHTF2 | 57157 | RNAseq | 0.3683 | 0.0509 | |
| SRP133303 | PHTF2 | 57157 | RNAseq | 0.7557 | 0.0000 | |
| SRP159526 | PHTF2 | 57157 | RNAseq | 0.3444 | 0.0706 | |
| SRP193095 | PHTF2 | 57157 | RNAseq | 0.2030 | 0.1711 | |
| SRP219564 | PHTF2 | 57157 | RNAseq | 0.3650 | 0.2421 | |
| TCGA | PHTF2 | 57157 | RNAseq | 0.2744 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PHTF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHTF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHTF2 | 57157 | 14 | 1 | 15 | |
| GSE20123 | PHTF2 | 57157 | 13 | 1 | 16 | |
| GSE43470 | PHTF2 | 57157 | 4 | 1 | 38 | |
| GSE46452 | PHTF2 | 57157 | 11 | 0 | 48 | |
| GSE47630 | PHTF2 | 57157 | 7 | 3 | 30 | |
| GSE54993 | PHTF2 | 57157 | 1 | 7 | 62 | |
| GSE54994 | PHTF2 | 57157 | 15 | 3 | 35 | |
| GSE60625 | PHTF2 | 57157 | 0 | 0 | 11 | |
| GSE74703 | PHTF2 | 57157 | 3 | 1 | 32 | |
| GSE74704 | PHTF2 | 57157 | 8 | 1 | 11 | |
| TCGA | PHTF2 | 57157 | 44 | 7 | 45 |
Total number of gains: 120; Total number of losses: 25; Total Number of normals: 343.
Somatic mutations of PHTF2:
Generating mutation plots.
Highly correlated genes for PHTF2:
Showing top 20/1056 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHTF2 | VEZT | 0.799701 | 3 | 0 | 3 |
| PHTF2 | ZNF121 | 0.78934 | 3 | 0 | 3 |
| PHTF2 | ACBD5 | 0.788991 | 3 | 0 | 3 |
| PHTF2 | ITGB8 | 0.784268 | 4 | 0 | 4 |
| PHTF2 | ALG1 | 0.769285 | 3 | 0 | 3 |
| PHTF2 | MDM2 | 0.742619 | 3 | 0 | 3 |
| PHTF2 | RRP36 | 0.741742 | 3 | 0 | 3 |
| PHTF2 | PRDM15 | 0.738284 | 3 | 0 | 3 |
| PHTF2 | C2orf69 | 0.737941 | 3 | 0 | 3 |
| PHTF2 | SMU1 | 0.730108 | 3 | 0 | 3 |
| PHTF2 | GSTCD | 0.729987 | 3 | 0 | 3 |
| PHTF2 | KLHDC2 | 0.725738 | 3 | 0 | 3 |
| PHTF2 | ZCCHC7 | 0.720148 | 3 | 0 | 3 |
| PHTF2 | GNPTAB | 0.719907 | 3 | 0 | 3 |
| PHTF2 | RILPL2 | 0.719436 | 3 | 0 | 3 |
| PHTF2 | CDC42SE2 | 0.711487 | 4 | 0 | 3 |
| PHTF2 | BCAR3 | 0.707104 | 3 | 0 | 3 |
| PHTF2 | KIAA0100 | 0.704375 | 3 | 0 | 3 |
| PHTF2 | LRRC58 | 0.702496 | 5 | 0 | 5 |
| PHTF2 | MRPS26 | 0.700822 | 3 | 0 | 3 |
For details and further investigation, click here
