| Full name: SMU1 DNA replication regulator and spliceosomal factor | Alias Symbol: SMU-1|FLJ10805|BWD|fSAP57 | ||
| Type: protein-coding gene | Cytoband: 9p21.1 | ||
| Entrez ID: 55234 | HGNC ID: HGNC:18247 | Ensembl Gene: ENSG00000122692 | OMIM ID: 617811 |
Expression of SMU1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMU1 | 55234 | 218393_s_at | -0.1542 | 0.7796 | |
| GSE20347 | SMU1 | 55234 | 218393_s_at | -0.1398 | 0.4104 | |
| GSE23400 | SMU1 | 55234 | 218393_s_at | 0.0045 | 0.9325 | |
| GSE26886 | SMU1 | 55234 | 222618_at | 0.5337 | 0.0529 | |
| GSE29001 | SMU1 | 55234 | 218393_s_at | 0.1324 | 0.4395 | |
| GSE38129 | SMU1 | 55234 | 218393_s_at | 0.0185 | 0.9143 | |
| GSE45670 | SMU1 | 55234 | 218393_s_at | 0.0384 | 0.8209 | |
| GSE63941 | SMU1 | 55234 | 218393_s_at | -0.2956 | 0.5994 | |
| GSE77861 | SMU1 | 55234 | 218393_s_at | 0.2058 | 0.6544 | |
| GSE97050 | SMU1 | 55234 | A_32_P68746 | 0.0099 | 0.9737 | |
| SRP007169 | SMU1 | 55234 | RNAseq | 0.5370 | 0.2763 | |
| SRP008496 | SMU1 | 55234 | RNAseq | 0.5403 | 0.0585 | |
| SRP064894 | SMU1 | 55234 | RNAseq | 0.1164 | 0.2731 | |
| SRP133303 | SMU1 | 55234 | RNAseq | -0.1006 | 0.3589 | |
| SRP159526 | SMU1 | 55234 | RNAseq | -0.2457 | 0.2530 | |
| SRP193095 | SMU1 | 55234 | RNAseq | -0.1580 | 0.1450 | |
| SRP219564 | SMU1 | 55234 | RNAseq | 0.1318 | 0.7140 | |
| TCGA | SMU1 | 55234 | RNAseq | 0.0209 | 0.6789 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SMU1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SMU1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMU1 | 55234 | 3 | 14 | 13 | |
| GSE20123 | SMU1 | 55234 | 3 | 14 | 13 | |
| GSE43470 | SMU1 | 55234 | 4 | 10 | 29 | |
| GSE46452 | SMU1 | 55234 | 7 | 15 | 37 | |
| GSE47630 | SMU1 | 55234 | 1 | 21 | 18 | |
| GSE54993 | SMU1 | 55234 | 6 | 0 | 64 | |
| GSE54994 | SMU1 | 55234 | 7 | 11 | 35 | |
| GSE60625 | SMU1 | 55234 | 0 | 0 | 11 | |
| GSE74703 | SMU1 | 55234 | 3 | 7 | 26 | |
| GSE74704 | SMU1 | 55234 | 0 | 11 | 9 | |
| TCGA | SMU1 | 55234 | 16 | 44 | 36 |
Total number of gains: 50; Total number of losses: 147; Total Number of normals: 291.
Somatic mutations of SMU1:
Generating mutation plots.
Highly correlated genes for SMU1:
Showing top 20/350 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMU1 | NHS | 0.812645 | 3 | 0 | 3 |
| SMU1 | MRPL44 | 0.80702 | 3 | 0 | 3 |
| SMU1 | MTO1 | 0.771252 | 3 | 0 | 3 |
| SMU1 | ERI2 | 0.770999 | 3 | 0 | 3 |
| SMU1 | UBE4A | 0.766094 | 3 | 0 | 3 |
| SMU1 | RRN3 | 0.758481 | 3 | 0 | 3 |
| SMU1 | CDC42SE2 | 0.750589 | 3 | 0 | 3 |
| SMU1 | VPS35 | 0.747436 | 3 | 0 | 3 |
| SMU1 | NCOA4 | 0.743062 | 3 | 0 | 3 |
| SMU1 | ZNF322 | 0.741049 | 3 | 0 | 3 |
| SMU1 | ZBTB26 | 0.730279 | 3 | 0 | 3 |
| SMU1 | PHTF2 | 0.730108 | 3 | 0 | 3 |
| SMU1 | ZNF700 | 0.726821 | 3 | 0 | 3 |
| SMU1 | CASC4 | 0.726034 | 3 | 0 | 3 |
| SMU1 | PPP2R5E | 0.725953 | 3 | 0 | 3 |
| SMU1 | OSBPL9 | 0.716356 | 4 | 0 | 4 |
| SMU1 | RAD17 | 0.716065 | 3 | 0 | 3 |
| SMU1 | ATF6 | 0.714916 | 4 | 0 | 4 |
| SMU1 | STRAP | 0.712847 | 3 | 0 | 3 |
| SMU1 | RILPL2 | 0.711749 | 3 | 0 | 3 |
For details and further investigation, click here
