| Full name: CDC42 small effector 2 | Alias Symbol: FLJ21967|SPEC2 | ||
| Type: protein-coding gene | Cytoband: 5q31.1 | ||
| Entrez ID: 56990 | HGNC ID: HGNC:18547 | Ensembl Gene: ENSG00000158985 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CDC42SE2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDC42SE2 | 56990 | 224709_s_at | 0.1483 | 0.8107 | |
| GSE26886 | CDC42SE2 | 56990 | 224709_s_at | 1.0940 | 0.0012 | |
| GSE45670 | CDC42SE2 | 56990 | 224709_s_at | -0.0707 | 0.7442 | |
| GSE53622 | CDC42SE2 | 56990 | 14052 | 0.1125 | 0.2253 | |
| GSE53624 | CDC42SE2 | 56990 | 14052 | 0.1341 | 0.1444 | |
| GSE63941 | CDC42SE2 | 56990 | 224709_s_at | 0.7681 | 0.0694 | |
| GSE77861 | CDC42SE2 | 56990 | 224709_s_at | 0.4958 | 0.1103 | |
| GSE97050 | CDC42SE2 | 56990 | A_24_P409042 | 0.1876 | 0.4998 | |
| SRP007169 | CDC42SE2 | 56990 | RNAseq | 0.8294 | 0.0209 | |
| SRP008496 | CDC42SE2 | 56990 | RNAseq | 0.8694 | 0.0002 | |
| SRP064894 | CDC42SE2 | 56990 | RNAseq | 0.2658 | 0.0765 | |
| SRP133303 | CDC42SE2 | 56990 | RNAseq | 0.3688 | 0.0776 | |
| SRP159526 | CDC42SE2 | 56990 | RNAseq | -0.0954 | 0.8419 | |
| SRP193095 | CDC42SE2 | 56990 | RNAseq | -0.1561 | 0.4110 | |
| SRP219564 | CDC42SE2 | 56990 | RNAseq | 0.4020 | 0.1766 | |
| TCGA | CDC42SE2 | 56990 | RNAseq | -0.0865 | 0.0849 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CDC42SE2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDC42SE2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDC42SE2 | 56990 | 1 | 12 | 17 | |
| GSE20123 | CDC42SE2 | 56990 | 1 | 12 | 17 | |
| GSE43470 | CDC42SE2 | 56990 | 2 | 9 | 32 | |
| GSE46452 | CDC42SE2 | 56990 | 0 | 27 | 32 | |
| GSE47630 | CDC42SE2 | 56990 | 0 | 21 | 19 | |
| GSE54993 | CDC42SE2 | 56990 | 9 | 1 | 60 | |
| GSE54994 | CDC42SE2 | 56990 | 2 | 14 | 37 | |
| GSE60625 | CDC42SE2 | 56990 | 0 | 0 | 11 | |
| GSE74703 | CDC42SE2 | 56990 | 2 | 6 | 28 | |
| GSE74704 | CDC42SE2 | 56990 | 1 | 6 | 13 | |
| TCGA | CDC42SE2 | 56990 | 3 | 39 | 54 |
Total number of gains: 21; Total number of losses: 147; Total Number of normals: 320.
Somatic mutations of CDC42SE2:
Generating mutation plots.
Highly correlated genes for CDC42SE2:
Showing top 20/734 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDC42SE2 | HDAC3 | 0.82024 | 3 | 0 | 3 |
| CDC42SE2 | ZNF655 | 0.792676 | 3 | 0 | 3 |
| CDC42SE2 | ATR | 0.791899 | 3 | 0 | 3 |
| CDC42SE2 | GLE1 | 0.769482 | 3 | 0 | 3 |
| CDC42SE2 | TOPBP1 | 0.765244 | 3 | 0 | 3 |
| CDC42SE2 | CD44 | 0.762137 | 4 | 0 | 4 |
| CDC42SE2 | DGCR2 | 0.760481 | 3 | 0 | 3 |
| CDC42SE2 | CERKL | 0.760129 | 3 | 0 | 3 |
| CDC42SE2 | PMPCB | 0.758531 | 3 | 0 | 3 |
| CDC42SE2 | STRN3 | 0.757269 | 3 | 0 | 3 |
| CDC42SE2 | FMR1 | 0.755729 | 4 | 0 | 4 |
| CDC42SE2 | VMA21 | 0.7513 | 3 | 0 | 3 |
| CDC42SE2 | LRP4 | 0.75121 | 3 | 0 | 3 |
| CDC42SE2 | SLC25A36 | 0.751047 | 3 | 0 | 3 |
| CDC42SE2 | SMU1 | 0.750589 | 3 | 0 | 3 |
| CDC42SE2 | MILR1 | 0.749083 | 4 | 0 | 4 |
| CDC42SE2 | STK3 | 0.748628 | 3 | 0 | 3 |
| CDC42SE2 | RIOK1 | 0.747817 | 3 | 0 | 3 |
| CDC42SE2 | U2SURP | 0.744107 | 3 | 0 | 3 |
| CDC42SE2 | AMMECR1L | 0.742468 | 3 | 0 | 3 |
For details and further investigation, click here
