| Full name: N-acetylglucosamine-1-phosphate transferase subunits alpha and beta | Alias Symbol: KIAA1208|MGC4170 | ||
| Type: protein-coding gene | Cytoband: 12q23.2 | ||
| Entrez ID: 79158 | HGNC ID: HGNC:29670 | Ensembl Gene: ENSG00000111670 | OMIM ID: 607840 |
| Drug and gene relationship at DGIdb | |||
Expression of GNPTAB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GNPTAB | 79158 | 212959_s_at | -0.2276 | 0.6462 | |
| GSE20347 | GNPTAB | 79158 | 212959_s_at | -0.1826 | 0.2882 | |
| GSE23400 | GNPTAB | 79158 | 212959_s_at | 0.2323 | 0.0102 | |
| GSE26886 | GNPTAB | 79158 | 212959_s_at | 0.4950 | 0.0511 | |
| GSE29001 | GNPTAB | 79158 | 212959_s_at | -0.2139 | 0.4745 | |
| GSE38129 | GNPTAB | 79158 | 212959_s_at | -0.0262 | 0.8566 | |
| GSE45670 | GNPTAB | 79158 | 212959_s_at | -0.1142 | 0.5237 | |
| GSE53622 | GNPTAB | 79158 | 45529 | -0.4523 | 0.0000 | |
| GSE53624 | GNPTAB | 79158 | 45529 | -0.1790 | 0.0011 | |
| GSE63941 | GNPTAB | 79158 | 212959_s_at | -1.2972 | 0.0274 | |
| GSE77861 | GNPTAB | 79158 | 212959_s_at | -0.1100 | 0.6078 | |
| GSE97050 | GNPTAB | 79158 | A_23_P346265 | -0.1150 | 0.6362 | |
| SRP007169 | GNPTAB | 79158 | RNAseq | 0.1007 | 0.7427 | |
| SRP008496 | GNPTAB | 79158 | RNAseq | 0.0229 | 0.9017 | |
| SRP064894 | GNPTAB | 79158 | RNAseq | 0.0560 | 0.8053 | |
| SRP133303 | GNPTAB | 79158 | RNAseq | 0.1088 | 0.4020 | |
| SRP159526 | GNPTAB | 79158 | RNAseq | 0.1580 | 0.4350 | |
| SRP193095 | GNPTAB | 79158 | RNAseq | -0.2355 | 0.0049 | |
| SRP219564 | GNPTAB | 79158 | RNAseq | -0.1254 | 0.6558 | |
| TCGA | GNPTAB | 79158 | RNAseq | -0.0815 | 0.0794 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GNPTAB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GNPTAB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GNPTAB | 79158 | 3 | 2 | 25 | |
| GSE20123 | GNPTAB | 79158 | 3 | 2 | 25 | |
| GSE43470 | GNPTAB | 79158 | 2 | 0 | 41 | |
| GSE46452 | GNPTAB | 79158 | 9 | 1 | 49 | |
| GSE47630 | GNPTAB | 79158 | 9 | 1 | 30 | |
| GSE54993 | GNPTAB | 79158 | 0 | 5 | 65 | |
| GSE54994 | GNPTAB | 79158 | 4 | 2 | 47 | |
| GSE60625 | GNPTAB | 79158 | 0 | 0 | 11 | |
| GSE74703 | GNPTAB | 79158 | 2 | 0 | 34 | |
| GSE74704 | GNPTAB | 79158 | 1 | 2 | 17 | |
| TCGA | GNPTAB | 79158 | 18 | 10 | 68 |
Total number of gains: 51; Total number of losses: 25; Total Number of normals: 412.
Somatic mutations of GNPTAB:
Generating mutation plots.
Highly correlated genes for GNPTAB:
Showing top 20/430 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GNPTAB | SRSF6 | 0.77556 | 3 | 0 | 3 |
| GNPTAB | RBBP6 | 0.772826 | 3 | 0 | 3 |
| GNPTAB | FAN1 | 0.760119 | 3 | 0 | 3 |
| GNPTAB | ABHD16A | 0.758979 | 3 | 0 | 3 |
| GNPTAB | PUS7L | 0.755795 | 3 | 0 | 3 |
| GNPTAB | MACROD2 | 0.742118 | 3 | 0 | 3 |
| GNPTAB | ZNF704 | 0.738303 | 3 | 0 | 3 |
| GNPTAB | NOLC1 | 0.73774 | 3 | 0 | 3 |
| GNPTAB | STK40 | 0.736509 | 3 | 0 | 3 |
| GNPTAB | ZNF322 | 0.732938 | 4 | 0 | 4 |
| GNPTAB | ZACN | 0.728451 | 3 | 0 | 3 |
| GNPTAB | PANK1 | 0.7281 | 4 | 0 | 4 |
| GNPTAB | FAM98B | 0.727807 | 3 | 0 | 3 |
| GNPTAB | SHPRH | 0.721456 | 4 | 0 | 3 |
| GNPTAB | PHTF2 | 0.719907 | 3 | 0 | 3 |
| GNPTAB | ZNF616 | 0.71239 | 3 | 0 | 3 |
| GNPTAB | NPHP3 | 0.710119 | 3 | 0 | 3 |
| GNPTAB | GALNT11 | 0.704812 | 3 | 0 | 3 |
| GNPTAB | SOCS6 | 0.704588 | 4 | 0 | 4 |
| GNPTAB | ENTPD4 | 0.700547 | 3 | 0 | 3 |
For details and further investigation, click here
