| Full name: KH-type splicing regulatory protein | Alias Symbol: KSRP|FBP2|FUBP2 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 8570 | HGNC ID: HGNC:6316 | Ensembl Gene: ENSG00000088247 | OMIM ID: 603445 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of KHSRP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KHSRP | 8570 | 204372_s_at | 0.6190 | 0.1511 | |
| GSE20347 | KHSRP | 8570 | 204372_s_at | 0.6192 | 0.0001 | |
| GSE23400 | KHSRP | 8570 | 204372_s_at | 0.5032 | 0.0000 | |
| GSE26886 | KHSRP | 8570 | 204372_s_at | 1.2690 | 0.0000 | |
| GSE29001 | KHSRP | 8570 | 204372_s_at | 0.5775 | 0.1565 | |
| GSE38129 | KHSRP | 8570 | 204372_s_at | 0.6382 | 0.0000 | |
| GSE45670 | KHSRP | 8570 | 204372_s_at | 0.4458 | 0.0006 | |
| GSE53622 | KHSRP | 8570 | 97309 | -0.0579 | 0.2470 | |
| GSE53624 | KHSRP | 8570 | 97309 | 0.1110 | 0.0021 | |
| GSE63941 | KHSRP | 8570 | 204372_s_at | 0.3895 | 0.1490 | |
| GSE77861 | KHSRP | 8570 | 204372_s_at | 0.6686 | 0.0011 | |
| GSE97050 | KHSRP | 8570 | A_23_P16157 | 0.2874 | 0.2422 | |
| SRP007169 | KHSRP | 8570 | RNAseq | 1.9341 | 0.0004 | |
| SRP008496 | KHSRP | 8570 | RNAseq | 1.8624 | 0.0000 | |
| SRP064894 | KHSRP | 8570 | RNAseq | 0.4997 | 0.0037 | |
| SRP133303 | KHSRP | 8570 | RNAseq | 0.5129 | 0.0105 | |
| SRP159526 | KHSRP | 8570 | RNAseq | 0.4811 | 0.0049 | |
| SRP193095 | KHSRP | 8570 | RNAseq | 0.5141 | 0.0000 | |
| SRP219564 | KHSRP | 8570 | RNAseq | 0.4644 | 0.0343 | |
| TCGA | KHSRP | 8570 | RNAseq | 0.1612 | 0.0001 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by KHSRP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KHSRP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KHSRP | 8570 | 5 | 3 | 22 | |
| GSE20123 | KHSRP | 8570 | 4 | 2 | 24 | |
| GSE43470 | KHSRP | 8570 | 2 | 6 | 35 | |
| GSE46452 | KHSRP | 8570 | 47 | 1 | 11 | |
| GSE47630 | KHSRP | 8570 | 5 | 7 | 28 | |
| GSE54993 | KHSRP | 8570 | 16 | 3 | 51 | |
| GSE54994 | KHSRP | 8570 | 6 | 14 | 33 | |
| GSE60625 | KHSRP | 8570 | 9 | 0 | 2 | |
| GSE74703 | KHSRP | 8570 | 2 | 4 | 30 | |
| GSE74704 | KHSRP | 8570 | 1 | 2 | 17 | |
| TCGA | KHSRP | 8570 | 9 | 19 | 68 |
Total number of gains: 106; Total number of losses: 61; Total Number of normals: 321.
Somatic mutations of KHSRP:
Generating mutation plots.
Highly correlated genes for KHSRP:
Showing top 20/1827 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KHSRP | XPR1 | 0.840119 | 4 | 0 | 4 |
| KHSRP | WDR54 | 0.833613 | 4 | 0 | 4 |
| KHSRP | ITM2C | 0.818336 | 3 | 0 | 3 |
| KHSRP | EXOC6 | 0.815917 | 3 | 0 | 3 |
| KHSRP | KCNAB2 | 0.815053 | 3 | 0 | 3 |
| KHSRP | GLIS2 | 0.813583 | 3 | 0 | 3 |
| KHSRP | PKIG | 0.810495 | 3 | 0 | 3 |
| KHSRP | B3GALT6 | 0.810373 | 4 | 0 | 4 |
| KHSRP | ZNF518B | 0.806837 | 3 | 0 | 3 |
| KHSRP | BRAT1 | 0.806402 | 4 | 0 | 4 |
| KHSRP | ZNF628 | 0.797861 | 4 | 0 | 3 |
| KHSRP | ZNF451 | 0.79666 | 3 | 0 | 3 |
| KHSRP | PLXNA1 | 0.791597 | 8 | 0 | 8 |
| KHSRP | SSBP4 | 0.791182 | 5 | 0 | 5 |
| KHSRP | HAS3 | 0.789925 | 3 | 0 | 3 |
| KHSRP | LMNB2 | 0.788803 | 7 | 0 | 7 |
| KHSRP | NACC1 | 0.786228 | 6 | 0 | 6 |
| KHSRP | MTBP | 0.779502 | 3 | 0 | 3 |
| KHSRP | COMMD7 | 0.772686 | 3 | 0 | 3 |
| KHSRP | ZNF789 | 0.772177 | 3 | 0 | 3 |
For details and further investigation, click here
