| Full name: DNA polymerase mu | Alias Symbol: Tdt-N | ||
| Type: protein-coding gene | Cytoband: 7p13 | ||
| Entrez ID: 27434 | HGNC ID: HGNC:9185 | Ensembl Gene: ENSG00000122678 | OMIM ID: 606344 |
| Drug and gene relationship at DGIdb | |||
Expression of POLM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POLM | 27434 | 222238_s_at | -0.0111 | 0.9761 | |
| GSE20347 | POLM | 27434 | 222238_s_at | -0.0434 | 0.6790 | |
| GSE23400 | POLM | 27434 | 222238_s_at | -0.1399 | 0.0041 | |
| GSE26886 | POLM | 27434 | 222238_s_at | 0.0196 | 0.9270 | |
| GSE29001 | POLM | 27434 | 222238_s_at | -0.1969 | 0.2456 | |
| GSE38129 | POLM | 27434 | 222238_s_at | -0.0369 | 0.7108 | |
| GSE45670 | POLM | 27434 | 222238_s_at | 0.2608 | 0.0750 | |
| GSE53622 | POLM | 27434 | 35959 | -0.0500 | 0.3159 | |
| GSE53624 | POLM | 27434 | 35959 | -0.1672 | 0.0292 | |
| GSE63941 | POLM | 27434 | 222238_s_at | 0.9828 | 0.0184 | |
| GSE77861 | POLM | 27434 | 222238_s_at | 0.0415 | 0.8560 | |
| GSE97050 | POLM | 27434 | A_33_P3391097 | 0.0470 | 0.8362 | |
| SRP007169 | POLM | 27434 | RNAseq | -1.2940 | 0.0012 | |
| SRP008496 | POLM | 27434 | RNAseq | -0.7635 | 0.0334 | |
| SRP064894 | POLM | 27434 | RNAseq | 0.1146 | 0.4612 | |
| SRP133303 | POLM | 27434 | RNAseq | -0.2873 | 0.0763 | |
| SRP159526 | POLM | 27434 | RNAseq | -0.0301 | 0.8829 | |
| SRP193095 | POLM | 27434 | RNAseq | -0.1142 | 0.4952 | |
| SRP219564 | POLM | 27434 | RNAseq | 0.0550 | 0.9015 | |
| TCGA | POLM | 27434 | RNAseq | -0.0558 | 0.3594 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by POLM expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POLM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POLM | 27434 | 14 | 0 | 16 | |
| GSE20123 | POLM | 27434 | 13 | 0 | 17 | |
| GSE43470 | POLM | 27434 | 4 | 0 | 39 | |
| GSE46452 | POLM | 27434 | 11 | 1 | 47 | |
| GSE47630 | POLM | 27434 | 8 | 1 | 31 | |
| GSE54993 | POLM | 27434 | 0 | 8 | 62 | |
| GSE54994 | POLM | 27434 | 17 | 3 | 33 | |
| GSE60625 | POLM | 27434 | 0 | 0 | 11 | |
| GSE74703 | POLM | 27434 | 4 | 0 | 32 | |
| GSE74704 | POLM | 27434 | 7 | 0 | 13 | |
| TCGA | POLM | 27434 | 51 | 7 | 38 |
Total number of gains: 129; Total number of losses: 20; Total Number of normals: 339.
Somatic mutations of POLM:
Generating mutation plots.
Highly correlated genes for POLM:
Showing top 20/363 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POLM | OR2C1 | 0.813246 | 3 | 0 | 3 |
| POLM | PLA2G2D | 0.805314 | 4 | 0 | 4 |
| POLM | DCDC1 | 0.777906 | 3 | 0 | 3 |
| POLM | GJD4 | 0.772664 | 3 | 0 | 3 |
| POLM | YY2 | 0.769136 | 3 | 0 | 3 |
| POLM | INSC | 0.765903 | 3 | 0 | 3 |
| POLM | OR2T27 | 0.763277 | 3 | 0 | 3 |
| POLM | OR13G1 | 0.759146 | 3 | 0 | 3 |
| POLM | HAP1 | 0.756631 | 3 | 0 | 3 |
| POLM | ASRGL1 | 0.753871 | 3 | 0 | 3 |
| POLM | TNFAIP8L1 | 0.753383 | 3 | 0 | 3 |
| POLM | TTC7A | 0.743957 | 3 | 0 | 3 |
| POLM | OTOG | 0.74299 | 3 | 0 | 3 |
| POLM | KCNJ13 | 0.741954 | 5 | 0 | 5 |
| POLM | TNR | 0.741849 | 5 | 0 | 5 |
| POLM | GDF7 | 0.739765 | 3 | 0 | 3 |
| POLM | NPPB | 0.73757 | 3 | 0 | 3 |
| POLM | ADM2 | 0.737389 | 4 | 0 | 3 |
| POLM | CABP4 | 0.731066 | 3 | 0 | 3 |
| POLM | CDHR5 | 0.731025 | 4 | 0 | 4 |
For details and further investigation, click here
