| Full name: transmembrane protein 106A | Alias Symbol: MGC20235 | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 113277 | HGNC ID: HGNC:28288 | Ensembl Gene: ENSG00000184988 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM106A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM106A | 113277 | 234580_at | -0.1282 | 0.6127 | |
| GSE26886 | TMEM106A | 113277 | 234580_at | -0.0631 | 0.6491 | |
| GSE45670 | TMEM106A | 113277 | 234580_at | -0.0117 | 0.9240 | |
| GSE53622 | TMEM106A | 113277 | 73505 | 0.6273 | 0.0000 | |
| GSE53624 | TMEM106A | 113277 | 73505 | 0.7834 | 0.0000 | |
| GSE63941 | TMEM106A | 113277 | 234580_at | 0.0796 | 0.5335 | |
| GSE77861 | TMEM106A | 113277 | 234580_at | -0.0935 | 0.4469 | |
| GSE97050 | TMEM106A | 113277 | A_33_P3370305 | 0.6376 | 0.1931 | |
| SRP007169 | TMEM106A | 113277 | RNAseq | 1.3367 | 0.0675 | |
| SRP064894 | TMEM106A | 113277 | RNAseq | 0.8935 | 0.0000 | |
| SRP133303 | TMEM106A | 113277 | RNAseq | 0.2930 | 0.1061 | |
| SRP159526 | TMEM106A | 113277 | RNAseq | 0.2760 | 0.5092 | |
| SRP193095 | TMEM106A | 113277 | RNAseq | 0.4921 | 0.0041 | |
| SRP219564 | TMEM106A | 113277 | RNAseq | 0.8800 | 0.0675 | |
| TCGA | TMEM106A | 113277 | RNAseq | -0.0509 | 0.6801 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM106A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM106A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM106A | 113277 | 6 | 2 | 22 | |
| GSE20123 | TMEM106A | 113277 | 6 | 2 | 22 | |
| GSE43470 | TMEM106A | 113277 | 1 | 2 | 40 | |
| GSE46452 | TMEM106A | 113277 | 34 | 0 | 25 | |
| GSE47630 | TMEM106A | 113277 | 8 | 1 | 31 | |
| GSE54993 | TMEM106A | 113277 | 3 | 4 | 63 | |
| GSE54994 | TMEM106A | 113277 | 8 | 5 | 40 | |
| GSE60625 | TMEM106A | 113277 | 4 | 0 | 7 | |
| GSE74703 | TMEM106A | 113277 | 1 | 1 | 34 | |
| GSE74704 | TMEM106A | 113277 | 4 | 1 | 15 | |
| TCGA | TMEM106A | 113277 | 22 | 7 | 67 |
Total number of gains: 97; Total number of losses: 25; Total Number of normals: 366.
Somatic mutations of TMEM106A:
Generating mutation plots.
Highly correlated genes for TMEM106A:
Showing top 20/222 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM106A | SARDH | 0.759855 | 3 | 0 | 3 |
| TMEM106A | CRCP | 0.735126 | 3 | 0 | 3 |
| TMEM106A | SP140 | 0.734235 | 3 | 0 | 3 |
| TMEM106A | PRELID1 | 0.729338 | 3 | 0 | 3 |
| TMEM106A | GALM | 0.719705 | 3 | 0 | 3 |
| TMEM106A | IL18BP | 0.712942 | 5 | 0 | 4 |
| TMEM106A | PARVG | 0.708556 | 3 | 0 | 3 |
| TMEM106A | DIAPH1 | 0.706998 | 3 | 0 | 3 |
| TMEM106A | CYTH4 | 0.701597 | 4 | 0 | 4 |
| TMEM106A | EIF3I | 0.698739 | 3 | 0 | 3 |
| TMEM106A | KCNJ14 | 0.687005 | 3 | 0 | 3 |
| TMEM106A | TRABD2B | 0.681641 | 3 | 0 | 3 |
| TMEM106A | TMEM141 | 0.679622 | 3 | 0 | 3 |
| TMEM106A | SDF4 | 0.679272 | 3 | 0 | 3 |
| TMEM106A | FLYWCH2 | 0.676331 | 3 | 0 | 3 |
| TMEM106A | SPI1 | 0.671552 | 4 | 0 | 4 |
| TMEM106A | RORC | 0.669914 | 3 | 0 | 3 |
| TMEM106A | MAST2 | 0.66427 | 3 | 0 | 3 |
| TMEM106A | PHACTR1 | 0.660144 | 3 | 0 | 3 |
| TMEM106A | IL32 | 0.659835 | 3 | 0 | 3 |
For details and further investigation, click here
