| Full name: ZFP36 ring finger protein like 2 | Alias Symbol: ERF2|RNF162C|TIS11D | ||
| Type: protein-coding gene | Cytoband: 2p21 | ||
| Entrez ID: 678 | HGNC ID: HGNC:1108 | Ensembl Gene: ENSG00000152518 | OMIM ID: 612053 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZFP36L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZFP36L2 | 678 | 201368_at | -0.4331 | 0.2172 | |
| GSE20347 | ZFP36L2 | 678 | 201368_at | -0.5105 | 0.0193 | |
| GSE23400 | ZFP36L2 | 678 | 201368_at | -0.4418 | 0.0000 | |
| GSE26886 | ZFP36L2 | 678 | 201368_at | -0.9303 | 0.0028 | |
| GSE29001 | ZFP36L2 | 678 | 201368_at | -0.8940 | 0.0014 | |
| GSE38129 | ZFP36L2 | 678 | 201368_at | -0.6538 | 0.0001 | |
| GSE45670 | ZFP36L2 | 678 | 201368_at | -0.9151 | 0.0000 | |
| GSE53622 | ZFP36L2 | 678 | 66766 | -0.7353 | 0.0000 | |
| GSE53624 | ZFP36L2 | 678 | 66766 | -0.7734 | 0.0000 | |
| GSE63941 | ZFP36L2 | 678 | 201368_at | -1.6514 | 0.0694 | |
| GSE77861 | ZFP36L2 | 678 | 201368_at | -0.4411 | 0.0357 | |
| GSE97050 | ZFP36L2 | 678 | A_23_P101960 | 0.1612 | 0.5647 | |
| SRP007169 | ZFP36L2 | 678 | RNAseq | -1.2244 | 0.0000 | |
| SRP008496 | ZFP36L2 | 678 | RNAseq | -1.6492 | 0.0000 | |
| SRP064894 | ZFP36L2 | 678 | RNAseq | -0.3377 | 0.1054 | |
| SRP133303 | ZFP36L2 | 678 | RNAseq | -0.5392 | 0.0051 | |
| SRP159526 | ZFP36L2 | 678 | RNAseq | -0.5468 | 0.0126 | |
| SRP193095 | ZFP36L2 | 678 | RNAseq | -0.5657 | 0.0034 | |
| SRP219564 | ZFP36L2 | 678 | RNAseq | 0.0179 | 0.9586 | |
| TCGA | ZFP36L2 | 678 | RNAseq | -0.2134 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ZFP36L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZFP36L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZFP36L2 | 678 | 12 | 2 | 16 | |
| GSE20123 | ZFP36L2 | 678 | 11 | 2 | 17 | |
| GSE43470 | ZFP36L2 | 678 | 3 | 1 | 39 | |
| GSE46452 | ZFP36L2 | 678 | 1 | 4 | 54 | |
| GSE47630 | ZFP36L2 | 678 | 7 | 0 | 33 | |
| GSE54993 | ZFP36L2 | 678 | 0 | 5 | 65 | |
| GSE54994 | ZFP36L2 | 678 | 9 | 1 | 43 | |
| GSE60625 | ZFP36L2 | 678 | 0 | 3 | 8 | |
| GSE74703 | ZFP36L2 | 678 | 3 | 1 | 32 | |
| GSE74704 | ZFP36L2 | 678 | 10 | 1 | 9 | |
| TCGA | ZFP36L2 | 678 | 35 | 2 | 59 |
Total number of gains: 91; Total number of losses: 22; Total Number of normals: 375.
Somatic mutations of ZFP36L2:
Generating mutation plots.
Highly correlated genes for ZFP36L2:
Showing top 20/973 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZFP36L2 | APIP | 0.787063 | 3 | 0 | 3 |
| ZFP36L2 | THUMPD3 | 0.740859 | 3 | 0 | 3 |
| ZFP36L2 | PHLDB1 | 0.74075 | 3 | 0 | 3 |
| ZFP36L2 | TIRAP | 0.740348 | 3 | 0 | 3 |
| ZFP36L2 | ARL4C | 0.738295 | 3 | 0 | 3 |
| ZFP36L2 | NAGA | 0.736638 | 3 | 0 | 3 |
| ZFP36L2 | GPBP1 | 0.731222 | 3 | 0 | 3 |
| ZFP36L2 | MTIF3 | 0.728325 | 3 | 0 | 3 |
| ZFP36L2 | PLXNA4 | 0.714601 | 3 | 0 | 3 |
| ZFP36L2 | PIGP | 0.711043 | 3 | 0 | 3 |
| ZFP36L2 | UBE2E2 | 0.709132 | 4 | 0 | 3 |
| ZFP36L2 | ESYT2 | 0.70597 | 3 | 0 | 3 |
| ZFP36L2 | ZNF829 | 0.703891 | 3 | 0 | 3 |
| ZFP36L2 | FAM47A | 0.7001 | 3 | 0 | 3 |
| ZFP36L2 | FAM193A | 0.697049 | 3 | 0 | 3 |
| ZFP36L2 | PIGA | 0.695383 | 3 | 0 | 3 |
| ZFP36L2 | SNAP29 | 0.693502 | 3 | 0 | 3 |
| ZFP36L2 | TRIP4 | 0.691071 | 4 | 0 | 3 |
| ZFP36L2 | NR5A2 | 0.690506 | 4 | 0 | 3 |
| ZFP36L2 | SLC41A2 | 0.686531 | 3 | 0 | 3 |
For details and further investigation, click here
