| Full name: peptidase M20 domain containing 2 | Alias Symbol: bA63L7.3 | ||
| Type: protein-coding gene | Cytoband: 6q15 | ||
| Entrez ID: 135293 | HGNC ID: HGNC:21408 | Ensembl Gene: ENSG00000146281 | OMIM ID: 615913 |
| Drug and gene relationship at DGIdb | |||
Expression of PM20D2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PM20D2 | 135293 | 225421_at | -0.1891 | 0.8117 | |
| GSE26886 | PM20D2 | 135293 | 225421_at | -0.2176 | 0.6204 | |
| GSE45670 | PM20D2 | 135293 | 225421_at | -0.1801 | 0.5781 | |
| GSE53622 | PM20D2 | 135293 | 95474 | 0.0042 | 0.9645 | |
| GSE53624 | PM20D2 | 135293 | 95474 | 0.0623 | 0.3886 | |
| GSE63941 | PM20D2 | 135293 | 225431_x_at | 1.5149 | 0.0108 | |
| GSE77861 | PM20D2 | 135293 | 225421_at | 0.2968 | 0.5654 | |
| GSE97050 | PM20D2 | 135293 | A_32_P86118 | -0.0468 | 0.8319 | |
| SRP007169 | PM20D2 | 135293 | RNAseq | 0.8202 | 0.0897 | |
| SRP008496 | PM20D2 | 135293 | RNAseq | 0.6959 | 0.0239 | |
| SRP064894 | PM20D2 | 135293 | RNAseq | 0.0256 | 0.9230 | |
| SRP133303 | PM20D2 | 135293 | RNAseq | 0.0378 | 0.8055 | |
| SRP159526 | PM20D2 | 135293 | RNAseq | 0.0037 | 0.9875 | |
| SRP193095 | PM20D2 | 135293 | RNAseq | -0.0716 | 0.5330 | |
| SRP219564 | PM20D2 | 135293 | RNAseq | 0.1681 | 0.7213 | |
| TCGA | PM20D2 | 135293 | RNAseq | 0.0280 | 0.6701 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PM20D2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PM20D2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PM20D2 | 135293 | 1 | 4 | 25 | |
| GSE20123 | PM20D2 | 135293 | 1 | 3 | 26 | |
| GSE43470 | PM20D2 | 135293 | 3 | 1 | 39 | |
| GSE46452 | PM20D2 | 135293 | 2 | 11 | 46 | |
| GSE47630 | PM20D2 | 135293 | 8 | 6 | 26 | |
| GSE54993 | PM20D2 | 135293 | 3 | 2 | 65 | |
| GSE54994 | PM20D2 | 135293 | 8 | 8 | 37 | |
| GSE60625 | PM20D2 | 135293 | 0 | 1 | 10 | |
| GSE74703 | PM20D2 | 135293 | 3 | 1 | 32 | |
| GSE74704 | PM20D2 | 135293 | 0 | 2 | 18 | |
| TCGA | PM20D2 | 135293 | 7 | 21 | 68 |
Total number of gains: 36; Total number of losses: 60; Total Number of normals: 392.
Somatic mutations of PM20D2:
Generating mutation plots.
Highly correlated genes for PM20D2:
Showing all 18 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PM20D2 | SNHG4 | 0.641677 | 3 | 0 | 3 |
| PM20D2 | CDK16 | 0.6157 | 3 | 0 | 3 |
| PM20D2 | MCF2L | 0.607105 | 4 | 0 | 3 |
| PM20D2 | AKAP1 | 0.594567 | 6 | 0 | 5 |
| PM20D2 | RTN4RL1 | 0.58882 | 3 | 0 | 3 |
| PM20D2 | RPL9 | 0.573582 | 4 | 0 | 3 |
| PM20D2 | ZNF84 | 0.56731 | 4 | 0 | 3 |
| PM20D2 | RPL31 | 0.558647 | 4 | 0 | 3 |
| PM20D2 | SOSTDC1 | 0.557955 | 4 | 0 | 3 |
| PM20D2 | ACVR2B | 0.557419 | 5 | 0 | 3 |
| PM20D2 | PHF10 | 0.554994 | 5 | 0 | 3 |
| PM20D2 | CCNT2 | 0.552976 | 3 | 0 | 3 |
| PM20D2 | TANK | 0.543469 | 4 | 0 | 3 |
| PM20D2 | WDSUB1 | 0.536717 | 4 | 0 | 3 |
| PM20D2 | RPARP-AS1 | 0.528451 | 5 | 0 | 3 |
| PM20D2 | COA1 | 0.526791 | 3 | 0 | 3 |
| PM20D2 | NTF3 | 0.521281 | 4 | 0 | 3 |
| PM20D2 | ZNF302 | 0.507706 | 6 | 0 | 3 |
For details and further investigation, click here
