| Full name: cytochrome c oxidase assembly factor 1 homolog | Alias Symbol: FLJ10803|MITRAC15 | ||
| Type: protein-coding gene | Cytoband: 7p13 | ||
| Entrez ID: 55744 | HGNC ID: HGNC:21868 | Ensembl Gene: ENSG00000106603 | OMIM ID: 614769 |
| Drug and gene relationship at DGIdb | |||
Expression of COA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COA1 | 55744 | 209445_x_at | 0.0519 | 0.9358 | |
| GSE20347 | COA1 | 55744 | 209445_x_at | 0.5615 | 0.0003 | |
| GSE23400 | COA1 | 55744 | 209445_x_at | 0.3736 | 0.0000 | |
| GSE26886 | COA1 | 55744 | 209445_x_at | -0.3216 | 0.1802 | |
| GSE29001 | COA1 | 55744 | 209445_x_at | 0.4899 | 0.1321 | |
| GSE38129 | COA1 | 55744 | 209445_x_at | 0.6611 | 0.0000 | |
| GSE45670 | COA1 | 55744 | 209445_x_at | 0.3970 | 0.0028 | |
| GSE53622 | COA1 | 55744 | 22872 | 0.6160 | 0.0000 | |
| GSE53624 | COA1 | 55744 | 22872 | 0.5500 | 0.0000 | |
| GSE63941 | COA1 | 55744 | 209445_x_at | 1.3134 | 0.0102 | |
| GSE77861 | COA1 | 55744 | 209445_x_at | 0.2530 | 0.5161 | |
| SRP007169 | COA1 | 55744 | RNAseq | -0.0661 | 0.8613 | |
| SRP008496 | COA1 | 55744 | RNAseq | 0.3131 | 0.3573 | |
| SRP064894 | COA1 | 55744 | RNAseq | 0.2883 | 0.1541 | |
| SRP133303 | COA1 | 55744 | RNAseq | 0.3717 | 0.0017 | |
| SRP159526 | COA1 | 55744 | RNAseq | 0.8540 | 0.0164 | |
| SRP193095 | COA1 | 55744 | RNAseq | 0.1694 | 0.0997 | |
| SRP219564 | COA1 | 55744 | RNAseq | 0.3392 | 0.3739 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by COA1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of COA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COA1 | 55744 | 14 | 0 | 16 | |
| GSE20123 | COA1 | 55744 | 13 | 0 | 17 | |
| GSE43470 | COA1 | 55744 | 4 | 0 | 39 | |
| GSE46452 | COA1 | 55744 | 11 | 1 | 47 | |
| GSE47630 | COA1 | 55744 | 8 | 1 | 31 | |
| GSE54993 | COA1 | 55744 | 0 | 8 | 62 | |
| GSE54994 | COA1 | 55744 | 17 | 3 | 33 | |
| GSE60625 | COA1 | 55744 | 0 | 0 | 11 | |
| GSE74703 | COA1 | 55744 | 4 | 0 | 32 | |
| GSE74704 | COA1 | 55744 | 7 | 0 | 13 | |
| TCGA | COA1 | 55744 | 50 | 7 | 39 |
Total number of gains: 128; Total number of losses: 20; Total Number of normals: 340.
Somatic mutations of COA1:
Generating mutation plots.
Highly correlated genes for COA1:
Showing top 20/498 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COA1 | NUDT1 | 0.708151 | 8 | 0 | 8 |
| COA1 | HIBADH | 0.698546 | 3 | 0 | 3 |
| COA1 | ZDHHC16 | 0.661109 | 4 | 0 | 4 |
| COA1 | RHBDD2 | 0.656608 | 3 | 0 | 3 |
| COA1 | PSMA2 | 0.653263 | 8 | 0 | 7 |
| COA1 | MRPL32 | 0.650675 | 5 | 0 | 4 |
| COA1 | MCM7 | 0.633211 | 9 | 0 | 7 |
| COA1 | POLD2 | 0.63196 | 10 | 0 | 8 |
| COA1 | RNF181 | 0.628586 | 4 | 0 | 3 |
| COA1 | HYLS1 | 0.626163 | 5 | 0 | 4 |
| COA1 | VKORC1 | 0.623876 | 4 | 0 | 3 |
| COA1 | SF3B6 | 0.62209 | 5 | 0 | 4 |
| COA1 | TMEM138 | 0.621496 | 3 | 0 | 3 |
| COA1 | PIGF | 0.620938 | 5 | 0 | 3 |
| COA1 | SSR2 | 0.620073 | 6 | 0 | 5 |
| COA1 | CDK4 | 0.619762 | 9 | 0 | 7 |
| COA1 | DUS4L | 0.617057 | 9 | 0 | 8 |
| COA1 | UBE2I | 0.615965 | 7 | 0 | 5 |
| COA1 | HARBI1 | 0.615678 | 3 | 0 | 3 |
| COA1 | SNRPB | 0.615218 | 10 | 0 | 8 |
For details and further investigation, click here
