| Full name: reticulon 4 receptor like 1 | Alias Symbol: NGRH2|NgR3|DKFZp547J144 | ||
| Type: protein-coding gene | Cytoband: 17p13.3 | ||
| Entrez ID: 146760 | HGNC ID: HGNC:21329 | Ensembl Gene: ENSG00000185924 | OMIM ID: 610461 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RTN4RL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RTN4RL1 | 146760 | 230700_at | 0.9703 | 0.2805 | |
| GSE26886 | RTN4RL1 | 146760 | 230700_at | 0.7802 | 0.0042 | |
| GSE45670 | RTN4RL1 | 146760 | 230700_at | 0.1431 | 0.4707 | |
| GSE53622 | RTN4RL1 | 146760 | 44306 | 0.7990 | 0.0000 | |
| GSE53624 | RTN4RL1 | 146760 | 44306 | 0.6657 | 0.0000 | |
| GSE63941 | RTN4RL1 | 146760 | 230700_at | 0.5691 | 0.0725 | |
| GSE77861 | RTN4RL1 | 146760 | 230700_at | 0.0032 | 0.9908 | |
| GSE97050 | RTN4RL1 | 146760 | A_23_P432056 | 0.3903 | 0.2151 | |
| SRP133303 | RTN4RL1 | 146760 | RNAseq | 0.5907 | 0.1429 | |
| SRP159526 | RTN4RL1 | 146760 | RNAseq | 1.2619 | 0.0444 | |
| SRP219564 | RTN4RL1 | 146760 | RNAseq | 2.1102 | 0.0001 | |
| TCGA | RTN4RL1 | 146760 | RNAseq | 0.5047 | 0.0624 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by RTN4RL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RTN4RL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RTN4RL1 | 146760 | 4 | 2 | 24 | |
| GSE20123 | RTN4RL1 | 146760 | 4 | 3 | 23 | |
| GSE43470 | RTN4RL1 | 146760 | 1 | 6 | 36 | |
| GSE46452 | RTN4RL1 | 146760 | 34 | 1 | 24 | |
| GSE47630 | RTN4RL1 | 146760 | 8 | 1 | 31 | |
| GSE54993 | RTN4RL1 | 146760 | 9 | 3 | 58 | |
| GSE54994 | RTN4RL1 | 146760 | 8 | 8 | 37 | |
| GSE60625 | RTN4RL1 | 146760 | 4 | 0 | 7 | |
| GSE74703 | RTN4RL1 | 146760 | 1 | 3 | 32 | |
| GSE74704 | RTN4RL1 | 146760 | 2 | 1 | 17 | |
| TCGA | RTN4RL1 | 146760 | 18 | 21 | 57 |
Total number of gains: 93; Total number of losses: 49; Total Number of normals: 346.
Somatic mutations of RTN4RL1:
Generating mutation plots.
Highly correlated genes for RTN4RL1:
Showing top 20/230 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RTN4RL1 | KLHDC4 | 0.81057 | 3 | 0 | 3 |
| RTN4RL1 | ITGA2B | 0.743682 | 3 | 0 | 3 |
| RTN4RL1 | GPT | 0.743502 | 3 | 0 | 3 |
| RTN4RL1 | MIIP | 0.736184 | 4 | 0 | 4 |
| RTN4RL1 | MBD6 | 0.734756 | 3 | 0 | 3 |
| RTN4RL1 | GPN2 | 0.707346 | 3 | 0 | 3 |
| RTN4RL1 | OPN3 | 0.704585 | 4 | 0 | 4 |
| RTN4RL1 | TRIM46 | 0.700112 | 4 | 0 | 4 |
| RTN4RL1 | MCM3AP-AS1 | 0.697368 | 3 | 0 | 3 |
| RTN4RL1 | C4orf47 | 0.695759 | 3 | 0 | 3 |
| RTN4RL1 | SEC62 | 0.694352 | 3 | 0 | 3 |
| RTN4RL1 | STK32C | 0.692375 | 5 | 0 | 5 |
| RTN4RL1 | SPATA2L | 0.688625 | 3 | 0 | 3 |
| RTN4RL1 | TRPM3 | 0.686521 | 3 | 0 | 3 |
| RTN4RL1 | HOMER1 | 0.685989 | 4 | 0 | 3 |
| RTN4RL1 | RIN1 | 0.679892 | 5 | 0 | 4 |
| RTN4RL1 | PATL2 | 0.679634 | 3 | 0 | 3 |
| RTN4RL1 | LTB4R2 | 0.679522 | 4 | 0 | 3 |
| RTN4RL1 | DOHH | 0.678461 | 4 | 0 | 4 |
| RTN4RL1 | CDH2 | 0.675357 | 3 | 0 | 3 |
For details and further investigation, click here
