| Full name: MCF.2 cell line derived transforming sequence like | Alias Symbol: KIAA0362|DBS|OST|ARHGEF14 | ||
| Type: protein-coding gene | Cytoband: 13q34 | ||
| Entrez ID: 23263 | HGNC ID: HGNC:14576 | Ensembl Gene: ENSG00000126217 | OMIM ID: 609499 |
| Drug and gene relationship at DGIdb | |||
Expression of MCF2L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MCF2L | 23263 | 212935_at | -0.3408 | 0.7153 | |
| GSE20347 | MCF2L | 23263 | 212935_at | 0.2176 | 0.6068 | |
| GSE23400 | MCF2L | 23263 | 35147_at | -0.1988 | 0.0157 | |
| GSE26886 | MCF2L | 23263 | 212935_at | 0.4675 | 0.3296 | |
| GSE29001 | MCF2L | 23263 | 35147_at | -0.1188 | 0.7786 | |
| GSE38129 | MCF2L | 23263 | 212935_at | 0.1390 | 0.6324 | |
| GSE45670 | MCF2L | 23263 | 212935_at | -0.4231 | 0.2074 | |
| GSE53622 | MCF2L | 23263 | 98381 | -0.0295 | 0.7301 | |
| GSE53624 | MCF2L | 23263 | 6272 | -0.6044 | 0.0000 | |
| GSE63941 | MCF2L | 23263 | 35147_at | 0.8877 | 0.2123 | |
| GSE77861 | MCF2L | 23263 | 1563808_at | -0.0695 | 0.7020 | |
| GSE97050 | MCF2L | 23263 | A_33_P3282018 | 0.0098 | 0.9691 | |
| SRP007169 | MCF2L | 23263 | RNAseq | 1.5837 | 0.0466 | |
| SRP064894 | MCF2L | 23263 | RNAseq | -0.3272 | 0.2663 | |
| SRP133303 | MCF2L | 23263 | RNAseq | -0.9309 | 0.0015 | |
| SRP159526 | MCF2L | 23263 | RNAseq | -0.4202 | 0.2067 | |
| SRP193095 | MCF2L | 23263 | RNAseq | -0.0893 | 0.7504 | |
| SRP219564 | MCF2L | 23263 | RNAseq | -0.3310 | 0.4637 | |
| TCGA | MCF2L | 23263 | RNAseq | -0.4581 | 0.0018 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MCF2L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MCF2L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MCF2L | 23263 | 7 | 12 | 11 | |
| GSE20123 | MCF2L | 23263 | 7 | 11 | 12 | |
| GSE43470 | MCF2L | 23263 | 4 | 14 | 25 | |
| GSE46452 | MCF2L | 23263 | 3 | 31 | 25 | |
| GSE47630 | MCF2L | 23263 | 3 | 26 | 11 | |
| GSE54993 | MCF2L | 23263 | 11 | 4 | 55 | |
| GSE54994 | MCF2L | 23263 | 10 | 9 | 34 | |
| GSE60625 | MCF2L | 23263 | 0 | 3 | 8 | |
| GSE74703 | MCF2L | 23263 | 3 | 10 | 23 | |
| GSE74704 | MCF2L | 23263 | 4 | 9 | 7 | |
| TCGA | MCF2L | 23263 | 20 | 32 | 44 |
Total number of gains: 72; Total number of losses: 161; Total Number of normals: 255.
Somatic mutations of MCF2L:
Generating mutation plots.
Highly correlated genes for MCF2L:
Showing top 20/99 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MCF2L | SIRPD | 0.861601 | 3 | 0 | 3 |
| MCF2L | HTR3A | 0.767536 | 3 | 0 | 3 |
| MCF2L | C11orf21 | 0.764036 | 3 | 0 | 3 |
| MCF2L | TTBK1 | 0.755228 | 3 | 0 | 3 |
| MCF2L | KIR3DL3 | 0.745709 | 3 | 0 | 3 |
| MCF2L | NRG2 | 0.742819 | 3 | 0 | 3 |
| MCF2L | U2AF1L4 | 0.718602 | 3 | 0 | 3 |
| MCF2L | CELF5 | 0.718479 | 3 | 0 | 3 |
| MCF2L | CCL25 | 0.716469 | 3 | 0 | 3 |
| MCF2L | GRTP1 | 0.715859 | 4 | 0 | 4 |
| MCF2L | PLA2G2D | 0.715648 | 4 | 0 | 4 |
| MCF2L | SRCIN1 | 0.703412 | 3 | 0 | 3 |
| MCF2L | GPR52 | 0.702331 | 3 | 0 | 3 |
| MCF2L | GJD4 | 0.701824 | 3 | 0 | 3 |
| MCF2L | SKAP1 | 0.70172 | 4 | 0 | 3 |
| MCF2L | SV2B | 0.699597 | 3 | 0 | 3 |
| MCF2L | PNPLA7 | 0.697456 | 3 | 0 | 3 |
| MCF2L | FXYD2 | 0.693712 | 3 | 0 | 3 |
| MCF2L | LRRC3 | 0.682374 | 3 | 0 | 3 |
| MCF2L | IQCF3 | 0.676721 | 3 | 0 | 3 |
For details and further investigation, click here
