| Full name: PHD finger protein 10 | Alias Symbol: FLJ10975|XAP135|BAF45a | ||
| Type: protein-coding gene | Cytoband: 6q27 | ||
| Entrez ID: 55274 | HGNC ID: HGNC:18250 | Ensembl Gene: ENSG00000130024 | OMIM ID: 613069 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PHF10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHF10 | 55274 | 219126_at | 0.1567 | 0.5815 | |
| GSE20347 | PHF10 | 55274 | 219126_at | -0.2155 | 0.1939 | |
| GSE23400 | PHF10 | 55274 | 219126_at | 0.0091 | 0.8947 | |
| GSE26886 | PHF10 | 55274 | 219126_at | -0.0596 | 0.8257 | |
| GSE29001 | PHF10 | 55274 | 219126_at | -0.2068 | 0.4677 | |
| GSE38129 | PHF10 | 55274 | 219126_at | -0.0052 | 0.9732 | |
| GSE45670 | PHF10 | 55274 | 219126_at | -0.0344 | 0.8322 | |
| GSE53622 | PHF10 | 55274 | 22701 | -0.8297 | 0.0000 | |
| GSE53624 | PHF10 | 55274 | 22701 | -0.8743 | 0.0000 | |
| GSE63941 | PHF10 | 55274 | 219126_at | -0.5519 | 0.2537 | |
| GSE77861 | PHF10 | 55274 | 219126_at | 0.0363 | 0.8237 | |
| GSE97050 | PHF10 | 55274 | A_23_P503200 | 0.1644 | 0.4966 | |
| SRP007169 | PHF10 | 55274 | RNAseq | 1.0538 | 0.0338 | |
| SRP008496 | PHF10 | 55274 | RNAseq | 0.4181 | 0.2465 | |
| SRP064894 | PHF10 | 55274 | RNAseq | -0.1620 | 0.2513 | |
| SRP133303 | PHF10 | 55274 | RNAseq | -0.1783 | 0.1852 | |
| SRP159526 | PHF10 | 55274 | RNAseq | -0.1868 | 0.5531 | |
| SRP193095 | PHF10 | 55274 | RNAseq | -0.3667 | 0.0000 | |
| SRP219564 | PHF10 | 55274 | RNAseq | -0.2708 | 0.3863 | |
| TCGA | PHF10 | 55274 | RNAseq | -0.1843 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PHF10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHF10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHF10 | 55274 | 4 | 6 | 20 | |
| GSE20123 | PHF10 | 55274 | 4 | 6 | 20 | |
| GSE43470 | PHF10 | 55274 | 2 | 0 | 41 | |
| GSE46452 | PHF10 | 55274 | 3 | 10 | 46 | |
| GSE47630 | PHF10 | 55274 | 7 | 7 | 26 | |
| GSE54993 | PHF10 | 55274 | 4 | 3 | 63 | |
| GSE54994 | PHF10 | 55274 | 10 | 8 | 35 | |
| GSE60625 | PHF10 | 55274 | 1 | 1 | 9 | |
| GSE74703 | PHF10 | 55274 | 2 | 0 | 34 | |
| GSE74704 | PHF10 | 55274 | 2 | 3 | 15 | |
| TCGA | PHF10 | 55274 | 14 | 20 | 62 |
Total number of gains: 53; Total number of losses: 64; Total Number of normals: 371.
Somatic mutations of PHF10:
Generating mutation plots.
Highly correlated genes for PHF10:
Showing top 20/21 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHF10 | GNAZ | 0.691897 | 3 | 0 | 3 |
| PHF10 | PLEKHA1 | 0.685358 | 3 | 0 | 3 |
| PHF10 | CDC20B | 0.67718 | 3 | 0 | 3 |
| PHF10 | ZBTB24 | 0.646712 | 5 | 0 | 3 |
| PHF10 | ATP6AP2 | 0.642861 | 4 | 0 | 3 |
| PHF10 | ARFGEF1 | 0.631472 | 4 | 0 | 3 |
| PHF10 | ZNF30 | 0.614202 | 4 | 0 | 3 |
| PHF10 | RPL7 | 0.595638 | 6 | 0 | 4 |
| PHF10 | PRPF8 | 0.588031 | 5 | 0 | 5 |
| PHF10 | TMEFF2 | 0.571819 | 4 | 0 | 3 |
| PHF10 | MCM9 | 0.559988 | 6 | 0 | 3 |
| PHF10 | MAP3K4 | 0.55715 | 7 | 0 | 4 |
| PHF10 | PM20D2 | 0.554994 | 5 | 0 | 3 |
| PHF10 | AUTS2 | 0.550968 | 5 | 0 | 3 |
| PHF10 | METTL18 | 0.543173 | 6 | 0 | 3 |
| PHF10 | SPIN1 | 0.52651 | 6 | 0 | 4 |
| PHF10 | TMEM248 | 0.525775 | 4 | 0 | 3 |
| PHF10 | SERBP1 | 0.521731 | 4 | 0 | 3 |
| PHF10 | C4orf46 | 0.517178 | 3 | 0 | 3 |
| PHF10 | SFRP1 | 0.507146 | 6 | 0 | 3 |
For details and further investigation, click here
