| Full name: pancreatic lipase related protein 1 | Alias Symbol: PLRP1 | ||
| Type: protein-coding gene | Cytoband: 10q25.3 | ||
| Entrez ID: 5407 | HGNC ID: HGNC:9156 | Ensembl Gene: ENSG00000187021 | OMIM ID: 604422 |
| Drug and gene relationship at DGIdb | |||
Expression of PNLIPRP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PNLIPRP1 | 5407 | 206694_at | -0.0987 | 0.7541 | |
| GSE20347 | PNLIPRP1 | 5407 | 206694_at | 0.0526 | 0.5456 | |
| GSE23400 | PNLIPRP1 | 5407 | 206694_at | -0.1581 | 0.0008 | |
| GSE26886 | PNLIPRP1 | 5407 | 206694_at | 0.0006 | 0.9965 | |
| GSE29001 | PNLIPRP1 | 5407 | 206694_at | -0.1573 | 0.3511 | |
| GSE38129 | PNLIPRP1 | 5407 | 206694_at | -0.1435 | 0.1511 | |
| GSE45670 | PNLIPRP1 | 5407 | 206694_at | -0.0296 | 0.7896 | |
| GSE53622 | PNLIPRP1 | 5407 | 24063 | 0.1540 | 0.0440 | |
| GSE53624 | PNLIPRP1 | 5407 | 24063 | -0.0422 | 0.6360 | |
| GSE63941 | PNLIPRP1 | 5407 | 206694_at | 0.4633 | 0.0104 | |
| GSE77861 | PNLIPRP1 | 5407 | 210722_at | -0.1108 | 0.3650 | |
| GSE97050 | PNLIPRP1 | 5407 | A_33_P3354646 | -0.0988 | 0.6627 | |
| TCGA | PNLIPRP1 | 5407 | RNAseq | 0.1865 | 0.9135 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PNLIPRP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PNLIPRP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PNLIPRP1 | 5407 | 1 | 7 | 22 | |
| GSE20123 | PNLIPRP1 | 5407 | 1 | 7 | 22 | |
| GSE43470 | PNLIPRP1 | 5407 | 0 | 9 | 34 | |
| GSE46452 | PNLIPRP1 | 5407 | 0 | 11 | 48 | |
| GSE47630 | PNLIPRP1 | 5407 | 2 | 14 | 24 | |
| GSE54993 | PNLIPRP1 | 5407 | 8 | 0 | 62 | |
| GSE54994 | PNLIPRP1 | 5407 | 1 | 9 | 43 | |
| GSE60625 | PNLIPRP1 | 5407 | 0 | 0 | 11 | |
| GSE74703 | PNLIPRP1 | 5407 | 0 | 6 | 30 | |
| GSE74704 | PNLIPRP1 | 5407 | 1 | 3 | 16 | |
| TCGA | PNLIPRP1 | 5407 | 4 | 28 | 64 |
Total number of gains: 18; Total number of losses: 94; Total Number of normals: 376.
Somatic mutations of PNLIPRP1:
Generating mutation plots.
Highly correlated genes for PNLIPRP1:
Showing top 20/1249 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PNLIPRP1 | STRC | 0.813986 | 3 | 0 | 3 |
| PNLIPRP1 | OR2A5 | 0.781956 | 3 | 0 | 3 |
| PNLIPRP1 | DCDC1 | 0.781586 | 3 | 0 | 3 |
| PNLIPRP1 | BSX | 0.772444 | 3 | 0 | 3 |
| PNLIPRP1 | SP8 | 0.770212 | 3 | 0 | 3 |
| PNLIPRP1 | PLA2G2C | 0.766277 | 3 | 0 | 3 |
| PNLIPRP1 | PRSS38 | 0.755513 | 3 | 0 | 3 |
| PNLIPRP1 | OR2H2 | 0.751231 | 6 | 0 | 6 |
| PNLIPRP1 | C1QL2 | 0.751132 | 3 | 0 | 3 |
| PNLIPRP1 | ASTN1 | 0.74621 | 3 | 0 | 3 |
| PNLIPRP1 | IL1F10 | 0.744321 | 3 | 0 | 3 |
| PNLIPRP1 | FOXA3 | 0.744268 | 3 | 0 | 3 |
| PNLIPRP1 | LCN9 | 0.743096 | 3 | 0 | 3 |
| PNLIPRP1 | SIGLEC7 | 0.74088 | 6 | 0 | 6 |
| PNLIPRP1 | SLC22A12 | 0.738938 | 4 | 0 | 4 |
| PNLIPRP1 | OR2T1 | 0.734476 | 3 | 0 | 3 |
| PNLIPRP1 | MRGPRE | 0.734379 | 3 | 0 | 3 |
| PNLIPRP1 | PABPN1L | 0.731545 | 3 | 0 | 3 |
| PNLIPRP1 | YY2 | 0.728978 | 3 | 0 | 3 |
| PNLIPRP1 | STXBP6 | 0.726929 | 3 | 0 | 3 |
For details and further investigation, click here
