| Full name: astrotactin 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q25.2 | ||
| Entrez ID: 460 | HGNC ID: HGNC:773 | Ensembl Gene: ENSG00000152092 | OMIM ID: 600904 |
| Drug and gene relationship at DGIdb | |||
Expression of ASTN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASTN1 | 460 | 213197_at | -0.4007 | 0.5984 | |
| GSE20347 | ASTN1 | 460 | 213197_at | 0.0159 | 0.8419 | |
| GSE23400 | ASTN1 | 460 | 213197_at | -0.0705 | 0.0182 | |
| GSE26886 | ASTN1 | 460 | 213197_at | 0.1290 | 0.1515 | |
| GSE29001 | ASTN1 | 460 | 213197_at | -0.1109 | 0.4071 | |
| GSE38129 | ASTN1 | 460 | 213197_at | -0.1814 | 0.0378 | |
| GSE45670 | ASTN1 | 460 | 213197_at | -0.0691 | 0.6080 | |
| GSE53622 | ASTN1 | 460 | 28480 | -2.3504 | 0.0000 | |
| GSE53624 | ASTN1 | 460 | 28480 | -2.7662 | 0.0000 | |
| GSE63941 | ASTN1 | 460 | 213197_at | 0.1701 | 0.6320 | |
| GSE77861 | ASTN1 | 460 | 213197_at | -0.0771 | 0.3592 | |
| GSE97050 | ASTN1 | 460 | A_33_P3220738 | -0.6335 | 0.1675 | |
| SRP133303 | ASTN1 | 460 | RNAseq | -1.0694 | 0.1747 | |
| TCGA | ASTN1 | 460 | RNAseq | -1.4506 | 0.0354 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ASTN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASTN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASTN1 | 460 | 11 | 0 | 19 | |
| GSE20123 | ASTN1 | 460 | 11 | 0 | 19 | |
| GSE43470 | ASTN1 | 460 | 7 | 2 | 34 | |
| GSE46452 | ASTN1 | 460 | 3 | 1 | 55 | |
| GSE47630 | ASTN1 | 460 | 14 | 0 | 26 | |
| GSE54993 | ASTN1 | 460 | 0 | 6 | 64 | |
| GSE54994 | ASTN1 | 460 | 15 | 0 | 38 | |
| GSE60625 | ASTN1 | 460 | 0 | 0 | 11 | |
| GSE74703 | ASTN1 | 460 | 7 | 2 | 27 | |
| GSE74704 | ASTN1 | 460 | 5 | 0 | 15 | |
| TCGA | ASTN1 | 460 | 40 | 3 | 53 |
Total number of gains: 113; Total number of losses: 14; Total Number of normals: 361.
Somatic mutations of ASTN1:
Generating mutation plots.
Highly correlated genes for ASTN1:
Showing top 20/525 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASTN1 | ADRB3 | 0.771367 | 3 | 0 | 3 |
| ASTN1 | SFRP5 | 0.764347 | 5 | 0 | 5 |
| ASTN1 | ZNF491 | 0.761212 | 3 | 0 | 3 |
| ASTN1 | ACADS | 0.759753 | 3 | 0 | 3 |
| ASTN1 | PNLIPRP1 | 0.74621 | 3 | 0 | 3 |
| ASTN1 | TACR1 | 0.727215 | 4 | 0 | 4 |
| ASTN1 | KCNQ4 | 0.717851 | 3 | 0 | 3 |
| ASTN1 | KIR2DS3 | 0.716562 | 3 | 0 | 3 |
| ASTN1 | OR1F1 | 0.710876 | 3 | 0 | 3 |
| ASTN1 | POLM | 0.703246 | 3 | 0 | 3 |
| ASTN1 | KRT4 | 0.701877 | 3 | 0 | 3 |
| ASTN1 | KRTAP20-1 | 0.699016 | 3 | 0 | 3 |
| ASTN1 | HRCT1 | 0.697837 | 4 | 0 | 4 |
| ASTN1 | MYOD1 | 0.693399 | 3 | 0 | 3 |
| ASTN1 | HSF4 | 0.693048 | 3 | 0 | 3 |
| ASTN1 | CRYAB | 0.693013 | 3 | 0 | 3 |
| ASTN1 | CRTC1 | 0.690269 | 5 | 0 | 4 |
| ASTN1 | FAM13C | 0.688539 | 3 | 0 | 3 |
| ASTN1 | CPNE6 | 0.684634 | 5 | 0 | 4 |
| ASTN1 | FAM163B | 0.683627 | 3 | 0 | 3 |
For details and further investigation, click here
