| Full name: protein O-fucosyltransferase 2 | Alias Symbol: KIAA0958|FUT13 | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 23275 | HGNC ID: HGNC:14683 | Ensembl Gene: ENSG00000186866 | OMIM ID: 610249 |
| Drug and gene relationship at DGIdb | |||
Expression of POFUT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POFUT2 | 23275 | 209578_s_at | 0.2814 | 0.4115 | |
| GSE20347 | POFUT2 | 23275 | 209578_s_at | 0.4293 | 0.0004 | |
| GSE23400 | POFUT2 | 23275 | 209578_s_at | 0.1623 | 0.0024 | |
| GSE26886 | POFUT2 | 23275 | 209578_s_at | 0.8491 | 0.0000 | |
| GSE29001 | POFUT2 | 23275 | 209578_s_at | 0.2251 | 0.1984 | |
| GSE38129 | POFUT2 | 23275 | 209578_s_at | 0.3532 | 0.0288 | |
| GSE45670 | POFUT2 | 23275 | 209578_s_at | 0.0476 | 0.8116 | |
| GSE53622 | POFUT2 | 23275 | 84510 | 0.4456 | 0.0000 | |
| GSE53624 | POFUT2 | 23275 | 84510 | 0.5539 | 0.0000 | |
| GSE63941 | POFUT2 | 23275 | 209578_s_at | -1.5570 | 0.0023 | |
| GSE77861 | POFUT2 | 23275 | 1555546_a_at | -0.0232 | 0.8804 | |
| GSE97050 | POFUT2 | 23275 | A_23_P211227 | 0.0737 | 0.7214 | |
| SRP007169 | POFUT2 | 23275 | RNAseq | 0.9914 | 0.2794 | |
| SRP008496 | POFUT2 | 23275 | RNAseq | 2.0185 | 0.0016 | |
| SRP064894 | POFUT2 | 23275 | RNAseq | 0.6262 | 0.0001 | |
| SRP133303 | POFUT2 | 23275 | RNAseq | 0.5454 | 0.0253 | |
| SRP159526 | POFUT2 | 23275 | RNAseq | 0.3869 | 0.1513 | |
| SRP193095 | POFUT2 | 23275 | RNAseq | 0.9673 | 0.0000 | |
| SRP219564 | POFUT2 | 23275 | RNAseq | 0.2842 | 0.4282 | |
| TCGA | POFUT2 | 23275 | RNAseq | -0.1694 | 0.0053 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by POFUT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POFUT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POFUT2 | 23275 | 2 | 8 | 20 | |
| GSE20123 | POFUT2 | 23275 | 2 | 8 | 20 | |
| GSE43470 | POFUT2 | 23275 | 0 | 13 | 30 | |
| GSE46452 | POFUT2 | 23275 | 1 | 21 | 37 | |
| GSE47630 | POFUT2 | 23275 | 6 | 17 | 17 | |
| GSE54993 | POFUT2 | 23275 | 8 | 1 | 61 | |
| GSE54994 | POFUT2 | 23275 | 5 | 8 | 40 | |
| GSE60625 | POFUT2 | 23275 | 0 | 0 | 11 | |
| GSE74703 | POFUT2 | 23275 | 0 | 10 | 26 | |
| GSE74704 | POFUT2 | 23275 | 1 | 4 | 15 | |
| TCGA | POFUT2 | 23275 | 9 | 38 | 49 |
Total number of gains: 34; Total number of losses: 128; Total Number of normals: 326.
Somatic mutations of POFUT2:
Generating mutation plots.
Highly correlated genes for POFUT2:
Showing top 20/556 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POFUT2 | POMGNT2 | 0.730019 | 3 | 0 | 3 |
| POFUT2 | SLC25A33 | 0.699814 | 3 | 0 | 3 |
| POFUT2 | TPM1 | 0.692273 | 3 | 0 | 3 |
| POFUT2 | ENOX1 | 0.682404 | 4 | 0 | 4 |
| POFUT2 | ADAMTS5 | 0.67823 | 3 | 0 | 3 |
| POFUT2 | ZFAS1 | 0.669941 | 4 | 0 | 3 |
| POFUT2 | TMEM263 | 0.669208 | 6 | 0 | 5 |
| POFUT2 | SLC39A13 | 0.668796 | 7 | 0 | 6 |
| POFUT2 | SMYD4 | 0.668304 | 4 | 0 | 4 |
| POFUT2 | WDR1 | 0.664384 | 3 | 0 | 3 |
| POFUT2 | BHMT2 | 0.653778 | 3 | 0 | 3 |
| POFUT2 | DZANK1 | 0.650335 | 4 | 0 | 4 |
| POFUT2 | FBRSL1 | 0.64877 | 3 | 0 | 3 |
| POFUT2 | LAMB1 | 0.648412 | 8 | 0 | 8 |
| POFUT2 | CHST15 | 0.647113 | 7 | 0 | 6 |
| POFUT2 | GGT7 | 0.646099 | 3 | 0 | 3 |
| POFUT2 | FKBP9 | 0.645017 | 7 | 0 | 6 |
| POFUT2 | MDC1 | 0.642389 | 7 | 0 | 5 |
| POFUT2 | BEND7 | 0.641321 | 3 | 0 | 3 |
| POFUT2 | C19orf12 | 0.640188 | 5 | 0 | 3 |
For details and further investigation, click here
