| Full name: ecto-NOX disulfide-thiol exchanger 1 | Alias Symbol: FLJ10094|PIG38|CNOX|cCNOX | ||
| Type: protein-coding gene | Cytoband: 13q14.11 | ||
| Entrez ID: 55068 | HGNC ID: HGNC:25474 | Ensembl Gene: ENSG00000120658 | OMIM ID: 610914 |
| Drug and gene relationship at DGIdb | |||
Expression of ENOX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ENOX1 | 55068 | 219501_at | 0.0960 | 0.9556 | |
| GSE20347 | ENOX1 | 55068 | 219501_at | 0.0900 | 0.4490 | |
| GSE23400 | ENOX1 | 55068 | 219501_at | -0.0798 | 0.0805 | |
| GSE26886 | ENOX1 | 55068 | 219501_at | 0.1382 | 0.2819 | |
| GSE29001 | ENOX1 | 55068 | 219501_at | -0.0425 | 0.7754 | |
| GSE38129 | ENOX1 | 55068 | 219501_at | -0.1675 | 0.4367 | |
| GSE45670 | ENOX1 | 55068 | 219501_at | -0.3379 | 0.5720 | |
| GSE53622 | ENOX1 | 55068 | 54695 | -0.1269 | 0.5648 | |
| GSE53624 | ENOX1 | 55068 | 54695 | 0.6229 | 0.0004 | |
| GSE63941 | ENOX1 | 55068 | 219501_at | -2.9595 | 0.0000 | |
| GSE77861 | ENOX1 | 55068 | 219501_at | -0.0049 | 0.9662 | |
| GSE97050 | ENOX1 | 55068 | A_23_P128574 | -0.3435 | 0.5673 | |
| SRP064894 | ENOX1 | 55068 | RNAseq | 1.2644 | 0.0003 | |
| SRP133303 | ENOX1 | 55068 | RNAseq | 0.7473 | 0.0320 | |
| SRP159526 | ENOX1 | 55068 | RNAseq | 0.3510 | 0.4070 | |
| SRP193095 | ENOX1 | 55068 | RNAseq | 0.5527 | 0.0043 | |
| SRP219564 | ENOX1 | 55068 | RNAseq | 0.4689 | 0.6343 | |
| TCGA | ENOX1 | 55068 | RNAseq | -0.9796 | 0.0008 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by ENOX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ENOX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ENOX1 | 55068 | 0 | 13 | 17 | |
| GSE20123 | ENOX1 | 55068 | 0 | 12 | 18 | |
| GSE43470 | ENOX1 | 55068 | 3 | 13 | 27 | |
| GSE46452 | ENOX1 | 55068 | 0 | 33 | 26 | |
| GSE47630 | ENOX1 | 55068 | 2 | 27 | 11 | |
| GSE54993 | ENOX1 | 55068 | 12 | 2 | 56 | |
| GSE54994 | ENOX1 | 55068 | 1 | 16 | 36 | |
| GSE60625 | ENOX1 | 55068 | 0 | 3 | 8 | |
| GSE74703 | ENOX1 | 55068 | 3 | 10 | 23 | |
| GSE74704 | ENOX1 | 55068 | 0 | 9 | 11 | |
| TCGA | ENOX1 | 55068 | 8 | 40 | 48 |
Total number of gains: 29; Total number of losses: 178; Total Number of normals: 281.
Somatic mutations of ENOX1:
Generating mutation plots.
Highly correlated genes for ENOX1:
Showing top 20/943 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ENOX1 | WFS1 | 0.761441 | 6 | 0 | 6 |
| ENOX1 | PCDH9 | 0.7486 | 6 | 0 | 5 |
| ENOX1 | NRXN3 | 0.73588 | 5 | 0 | 5 |
| ENOX1 | RGMB | 0.73208 | 5 | 0 | 5 |
| ENOX1 | ZNF610 | 0.728489 | 4 | 0 | 3 |
| ENOX1 | INMT | 0.72214 | 4 | 0 | 3 |
| ENOX1 | JAZF1 | 0.720545 | 4 | 0 | 4 |
| ENOX1 | ANXA6 | 0.718472 | 9 | 0 | 8 |
| ENOX1 | SPATA9 | 0.71414 | 4 | 0 | 3 |
| ENOX1 | LRCH2 | 0.712913 | 6 | 0 | 6 |
| ENOX1 | NEGR1 | 0.712675 | 4 | 0 | 4 |
| ENOX1 | CASQ1 | 0.706803 | 6 | 0 | 6 |
| ENOX1 | TMEM170B | 0.704045 | 6 | 0 | 6 |
| ENOX1 | RNF115 | 0.703513 | 4 | 0 | 4 |
| ENOX1 | ZNF25 | 0.70329 | 5 | 0 | 5 |
| ENOX1 | ZNF347 | 0.702911 | 3 | 0 | 3 |
| ENOX1 | GMPR | 0.701159 | 5 | 0 | 4 |
| ENOX1 | RASSF8 | 0.70049 | 6 | 0 | 6 |
| ENOX1 | TNFSF12 | 0.698843 | 3 | 0 | 3 |
| ENOX1 | DIXDC1 | 0.698342 | 7 | 0 | 6 |
For details and further investigation, click here
