| Full name: gamma-glutamyltransferase 7 | Alias Symbol: D20S101|dJ18C9.2 | ||
| Type: protein-coding gene | Cytoband: 20q11.22 | ||
| Entrez ID: 2686 | HGNC ID: HGNC:4259 | Ensembl Gene: ENSG00000131067 | OMIM ID: 612342 |
| Drug and gene relationship at DGIdb | |||
Expression of GGT7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GGT7 | 2686 | 226470_at | 0.3327 | 0.2802 | |
| GSE26886 | GGT7 | 2686 | 226470_at | 0.6632 | 0.0062 | |
| GSE45670 | GGT7 | 2686 | 226470_at | -0.0214 | 0.9318 | |
| GSE53622 | GGT7 | 2686 | 39653 | 0.0740 | 0.2908 | |
| GSE53624 | GGT7 | 2686 | 85546 | 0.3628 | 0.0000 | |
| GSE63941 | GGT7 | 2686 | 226470_at | -0.3988 | 0.5693 | |
| GSE77861 | GGT7 | 2686 | 226470_at | 0.3526 | 0.0317 | |
| GSE97050 | GGT7 | 2686 | A_23_P57236 | 0.1632 | 0.7301 | |
| SRP007169 | GGT7 | 2686 | RNAseq | 0.8841 | 0.0809 | |
| SRP008496 | GGT7 | 2686 | RNAseq | 1.2246 | 0.0077 | |
| SRP064894 | GGT7 | 2686 | RNAseq | 0.8161 | 0.0002 | |
| SRP133303 | GGT7 | 2686 | RNAseq | 0.3699 | 0.0412 | |
| SRP159526 | GGT7 | 2686 | RNAseq | 0.8518 | 0.0349 | |
| SRP193095 | GGT7 | 2686 | RNAseq | 0.7237 | 0.0009 | |
| SRP219564 | GGT7 | 2686 | RNAseq | 0.2306 | 0.6135 | |
| TCGA | GGT7 | 2686 | RNAseq | -0.2900 | 0.0521 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GGT7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GGT7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GGT7 | 2686 | 16 | 0 | 14 | |
| GSE20123 | GGT7 | 2686 | 16 | 0 | 14 | |
| GSE43470 | GGT7 | 2686 | 12 | 0 | 31 | |
| GSE46452 | GGT7 | 2686 | 29 | 0 | 30 | |
| GSE47630 | GGT7 | 2686 | 24 | 1 | 15 | |
| GSE54993 | GGT7 | 2686 | 0 | 18 | 52 | |
| GSE54994 | GGT7 | 2686 | 25 | 1 | 27 | |
| GSE60625 | GGT7 | 2686 | 0 | 0 | 11 | |
| GSE74703 | GGT7 | 2686 | 11 | 0 | 25 | |
| GSE74704 | GGT7 | 2686 | 11 | 0 | 9 | |
| TCGA | GGT7 | 2686 | 50 | 3 | 43 |
Total number of gains: 194; Total number of losses: 23; Total Number of normals: 271.
Somatic mutations of GGT7:
Generating mutation plots.
Highly correlated genes for GGT7:
Showing top 20/144 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GGT7 | PYGO2 | 0.784156 | 3 | 0 | 3 |
| GGT7 | RASL11B | 0.750545 | 3 | 0 | 3 |
| GGT7 | TCHH | 0.748503 | 3 | 0 | 3 |
| GGT7 | TCEAL3 | 0.731806 | 3 | 0 | 3 |
| GGT7 | COLGALT1 | 0.711345 | 3 | 0 | 3 |
| GGT7 | RAD54L2 | 0.689063 | 3 | 0 | 3 |
| GGT7 | TMEM263 | 0.673749 | 3 | 0 | 3 |
| GGT7 | SDK1 | 0.667194 | 3 | 0 | 3 |
| GGT7 | PLBD2 | 0.661614 | 3 | 0 | 3 |
| GGT7 | TP53BP1 | 0.661581 | 5 | 0 | 4 |
| GGT7 | BRD3 | 0.657078 | 4 | 0 | 4 |
| GGT7 | TOR3A | 0.656978 | 3 | 0 | 3 |
| GGT7 | DVL2 | 0.654749 | 4 | 0 | 4 |
| GGT7 | FZD9 | 0.652402 | 3 | 0 | 3 |
| GGT7 | FLAD1 | 0.651368 | 3 | 0 | 3 |
| GGT7 | TXNRD2 | 0.649408 | 3 | 0 | 3 |
| GGT7 | UBL4A | 0.64891 | 3 | 0 | 3 |
| GGT7 | NRIP3 | 0.646365 | 4 | 0 | 4 |
| GGT7 | POFUT2 | 0.646099 | 3 | 0 | 3 |
| GGT7 | VAMP4 | 0.643858 | 3 | 0 | 3 |
For details and further investigation, click here
