| Full name: double zinc ribbon and ankyrin repeat domains 1 | Alias Symbol: FLJ10600|dJ568F9.2|FLJ30892|bA189K21.8|ANKRD64 | ||
| Type: protein-coding gene | Cytoband: 20p11.23 | ||
| Entrez ID: 55184 | HGNC ID: HGNC:15858 | Ensembl Gene: ENSG00000089091 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DZANK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DZANK1 | 55184 | 219951_s_at | 0.5943 | 0.4048 | |
| GSE20347 | DZANK1 | 55184 | 219951_s_at | 0.2775 | 0.3479 | |
| GSE23400 | DZANK1 | 55184 | 219951_s_at | 0.0391 | 0.5411 | |
| GSE26886 | DZANK1 | 55184 | 219951_s_at | 0.8466 | 0.0011 | |
| GSE29001 | DZANK1 | 55184 | 219951_s_at | 0.2146 | 0.6145 | |
| GSE38129 | DZANK1 | 55184 | 219951_s_at | 0.2221 | 0.3032 | |
| GSE45670 | DZANK1 | 55184 | 219951_s_at | 0.1291 | 0.6783 | |
| GSE53622 | DZANK1 | 55184 | 83160 | 0.1872 | 0.0089 | |
| GSE53624 | DZANK1 | 55184 | 83160 | -0.4531 | 0.0000 | |
| GSE63941 | DZANK1 | 55184 | 219951_s_at | 0.0054 | 0.9946 | |
| GSE77861 | DZANK1 | 55184 | 1554818_s_at | -0.0185 | 0.8674 | |
| GSE97050 | DZANK1 | 55184 | A_23_P40315 | 0.1874 | 0.3594 | |
| SRP007169 | DZANK1 | 55184 | RNAseq | -1.1295 | 0.0504 | |
| SRP064894 | DZANK1 | 55184 | RNAseq | 0.7728 | 0.0001 | |
| SRP133303 | DZANK1 | 55184 | RNAseq | 0.1567 | 0.4314 | |
| SRP193095 | DZANK1 | 55184 | RNAseq | 0.4862 | 0.0123 | |
| SRP219564 | DZANK1 | 55184 | RNAseq | -0.1440 | 0.7331 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DZANK1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of DZANK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DZANK1 | 55184 | 12 | 2 | 16 | |
| GSE20123 | DZANK1 | 55184 | 12 | 2 | 16 | |
| GSE43470 | DZANK1 | 55184 | 11 | 1 | 31 | |
| GSE46452 | DZANK1 | 55184 | 27 | 1 | 31 | |
| GSE47630 | DZANK1 | 55184 | 17 | 4 | 19 | |
| GSE54993 | DZANK1 | 55184 | 0 | 15 | 55 | |
| GSE54994 | DZANK1 | 55184 | 26 | 2 | 25 | |
| GSE60625 | DZANK1 | 55184 | 0 | 0 | 11 | |
| GSE74703 | DZANK1 | 55184 | 8 | 1 | 27 | |
| GSE74704 | DZANK1 | 55184 | 7 | 2 | 11 | |
| TCGA | DZANK1 | 55184 | 44 | 10 | 42 |
Total number of gains: 164; Total number of losses: 40; Total Number of normals: 284.
Somatic mutations of DZANK1:
Generating mutation plots.
Highly correlated genes for DZANK1:
Showing top 20/183 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DZANK1 | FAM161A | 0.723601 | 3 | 0 | 3 |
| DZANK1 | RPN2 | 0.719521 | 3 | 0 | 3 |
| DZANK1 | DROSHA | 0.702446 | 3 | 0 | 3 |
| DZANK1 | RALGAPA2 | 0.699578 | 4 | 0 | 4 |
| DZANK1 | NOC2L | 0.694421 | 3 | 0 | 3 |
| DZANK1 | PMPCB | 0.691322 | 3 | 0 | 3 |
| DZANK1 | UHRF1BP1 | 0.689369 | 3 | 0 | 3 |
| DZANK1 | SRRT | 0.681998 | 4 | 0 | 3 |
| DZANK1 | USP42 | 0.675019 | 3 | 0 | 3 |
| DZANK1 | DCTN1-AS1 | 0.663181 | 3 | 0 | 3 |
| DZANK1 | SLC38A6 | 0.660158 | 4 | 0 | 4 |
| DZANK1 | ANAPC5 | 0.659723 | 3 | 0 | 3 |
| DZANK1 | ZNF805 | 0.65768 | 3 | 0 | 3 |
| DZANK1 | PDZK1 | 0.65554 | 3 | 0 | 3 |
| DZANK1 | ISY1 | 0.650945 | 3 | 0 | 3 |
| DZANK1 | SPEN | 0.650438 | 4 | 0 | 3 |
| DZANK1 | POFUT2 | 0.650335 | 4 | 0 | 4 |
| DZANK1 | ULK1 | 0.649796 | 3 | 0 | 3 |
| DZANK1 | FCHO1 | 0.648511 | 4 | 0 | 4 |
| DZANK1 | TRIT1 | 0.648392 | 3 | 0 | 3 |
For details and further investigation, click here
