| Full name: protein O-mannosyltransferase 2 | Alias Symbol: LGMD2N | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 29954 | HGNC ID: HGNC:19743 | Ensembl Gene: ENSG00000009830 | OMIM ID: 607439 |
| Drug and gene relationship at DGIdb | |||
Expression of POMT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POMT2 | 29954 | 225560_at | 0.3598 | 0.3752 | |
| GSE20347 | POMT2 | 29954 | 220632_s_at | 0.1495 | 0.1190 | |
| GSE23400 | POMT2 | 29954 | 220632_s_at | 0.0775 | 0.0217 | |
| GSE26886 | POMT2 | 29954 | 225560_at | 0.1764 | 0.3178 | |
| GSE29001 | POMT2 | 29954 | 220632_s_at | 0.1622 | 0.3244 | |
| GSE38129 | POMT2 | 29954 | 220632_s_at | 0.1114 | 0.1328 | |
| GSE45670 | POMT2 | 29954 | 220632_s_at | 0.2535 | 0.0046 | |
| GSE53622 | POMT2 | 29954 | 19221 | 0.3168 | 0.0004 | |
| GSE53624 | POMT2 | 29954 | 19221 | 0.6654 | 0.0000 | |
| GSE63941 | POMT2 | 29954 | 225560_at | -0.2300 | 0.4198 | |
| GSE77861 | POMT2 | 29954 | 220632_s_at | 0.0559 | 0.7044 | |
| GSE97050 | POMT2 | 29954 | A_24_P111134 | -0.1745 | 0.5209 | |
| SRP007169 | POMT2 | 29954 | RNAseq | 1.9811 | 0.0020 | |
| SRP008496 | POMT2 | 29954 | RNAseq | 2.3348 | 0.0001 | |
| SRP064894 | POMT2 | 29954 | RNAseq | 1.3369 | 0.0000 | |
| SRP133303 | POMT2 | 29954 | RNAseq | 0.7009 | 0.0002 | |
| SRP159526 | POMT2 | 29954 | RNAseq | 0.7423 | 0.0261 | |
| SRP193095 | POMT2 | 29954 | RNAseq | 0.9122 | 0.0000 | |
| SRP219564 | POMT2 | 29954 | RNAseq | 1.0862 | 0.0045 | |
| TCGA | POMT2 | 29954 | RNAseq | 0.1429 | 0.0208 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by POMT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POMT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POMT2 | 29954 | 8 | 3 | 19 | |
| GSE20123 | POMT2 | 29954 | 8 | 3 | 19 | |
| GSE43470 | POMT2 | 29954 | 8 | 3 | 32 | |
| GSE46452 | POMT2 | 29954 | 16 | 3 | 40 | |
| GSE47630 | POMT2 | 29954 | 11 | 8 | 21 | |
| GSE54993 | POMT2 | 29954 | 3 | 8 | 59 | |
| GSE54994 | POMT2 | 29954 | 19 | 4 | 30 | |
| GSE60625 | POMT2 | 29954 | 0 | 2 | 9 | |
| GSE74703 | POMT2 | 29954 | 7 | 3 | 26 | |
| GSE74704 | POMT2 | 29954 | 3 | 3 | 14 | |
| TCGA | POMT2 | 29954 | 32 | 16 | 48 |
Total number of gains: 115; Total number of losses: 56; Total Number of normals: 317.
Somatic mutations of POMT2:
Generating mutation plots.
Highly correlated genes for POMT2:
Showing top 20/200 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POMT2 | DNAL4 | 0.750034 | 4 | 0 | 4 |
| POMT2 | CES3 | 0.74626 | 3 | 0 | 3 |
| POMT2 | FBXO25 | 0.733573 | 3 | 0 | 3 |
| POMT2 | ZNF526 | 0.710174 | 4 | 0 | 4 |
| POMT2 | HIVEP2 | 0.705616 | 3 | 0 | 3 |
| POMT2 | AGER | 0.704979 | 3 | 0 | 3 |
| POMT2 | ZNF511 | 0.688459 | 4 | 0 | 3 |
| POMT2 | RETN | 0.686849 | 3 | 0 | 3 |
| POMT2 | PARS2 | 0.680305 | 3 | 0 | 3 |
| POMT2 | CDC6 | 0.680304 | 3 | 0 | 3 |
| POMT2 | WDR83 | 0.675143 | 4 | 0 | 3 |
| POMT2 | ATP7B | 0.667986 | 4 | 0 | 3 |
| POMT2 | ZNF182 | 0.664326 | 3 | 0 | 3 |
| POMT2 | RUSC1 | 0.661673 | 4 | 0 | 3 |
| POMT2 | SCLY | 0.661236 | 4 | 0 | 3 |
| POMT2 | LRR1 | 0.657613 | 5 | 0 | 4 |
| POMT2 | CCDC114 | 0.653168 | 3 | 0 | 3 |
| POMT2 | ZNF205 | 0.652892 | 6 | 0 | 4 |
| POMT2 | SSTR3 | 0.6504 | 4 | 0 | 4 |
| POMT2 | PCSK1N | 0.649932 | 4 | 0 | 3 |
For details and further investigation, click here
