| Full name: beta-1,4-N-acetyl-galactosaminyltransferase 1 | Alias Symbol: beta1-4GalNAc-T | ||
| Type: protein-coding gene | Cytoband: 12q13.3 | ||
| Entrez ID: 2583 | HGNC ID: HGNC:4117 | Ensembl Gene: ENSG00000135454 | OMIM ID: 601873 |
| Drug and gene relationship at DGIdb | |||
Expression of B4GALNT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | B4GALNT1 | 2583 | 206435_at | 0.1306 | 0.8690 | |
| GSE20347 | B4GALNT1 | 2583 | 206435_at | 0.6452 | 0.0004 | |
| GSE23400 | B4GALNT1 | 2583 | 206435_at | 0.1457 | 0.0061 | |
| GSE26886 | B4GALNT1 | 2583 | 206435_at | 1.0634 | 0.0000 | |
| GSE29001 | B4GALNT1 | 2583 | 206435_at | 0.3346 | 0.0912 | |
| GSE38129 | B4GALNT1 | 2583 | 206435_at | 0.6704 | 0.0003 | |
| GSE45670 | B4GALNT1 | 2583 | 206435_at | 0.6684 | 0.0005 | |
| GSE63941 | B4GALNT1 | 2583 | 206435_at | 0.9661 | 0.0244 | |
| GSE77861 | B4GALNT1 | 2583 | 206435_at | 0.3241 | 0.1462 | |
| GSE97050 | B4GALNT1 | 2583 | A_33_P3846177 | 0.3369 | 0.3790 | |
| SRP007169 | B4GALNT1 | 2583 | RNAseq | 6.2959 | 0.0000 | |
| SRP008496 | B4GALNT1 | 2583 | RNAseq | 6.8527 | 0.0000 | |
| SRP064894 | B4GALNT1 | 2583 | RNAseq | 2.1894 | 0.0000 | |
| SRP133303 | B4GALNT1 | 2583 | RNAseq | 2.5205 | 0.0000 | |
| SRP159526 | B4GALNT1 | 2583 | RNAseq | 3.6625 | 0.0000 | |
| SRP219564 | B4GALNT1 | 2583 | RNAseq | 1.9128 | 0.0270 | |
| TCGA | B4GALNT1 | 2583 | RNAseq | 1.3919 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by B4GALNT1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of B4GALNT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | B4GALNT1 | 2583 | 7 | 1 | 22 | |
| GSE20123 | B4GALNT1 | 2583 | 7 | 0 | 23 | |
| GSE43470 | B4GALNT1 | 2583 | 2 | 0 | 41 | |
| GSE46452 | B4GALNT1 | 2583 | 8 | 1 | 50 | |
| GSE47630 | B4GALNT1 | 2583 | 10 | 2 | 28 | |
| GSE54993 | B4GALNT1 | 2583 | 0 | 5 | 65 | |
| GSE54994 | B4GALNT1 | 2583 | 4 | 1 | 48 | |
| GSE60625 | B4GALNT1 | 2583 | 0 | 0 | 11 | |
| GSE74703 | B4GALNT1 | 2583 | 2 | 0 | 34 | |
| GSE74704 | B4GALNT1 | 2583 | 5 | 0 | 15 | |
| TCGA | B4GALNT1 | 2583 | 14 | 10 | 72 |
Total number of gains: 59; Total number of losses: 20; Total Number of normals: 409.
Somatic mutations of B4GALNT1:
Generating mutation plots.
Highly correlated genes for B4GALNT1:
Showing top 20/627 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| B4GALNT1 | IL31RA | 0.74868 | 3 | 0 | 3 |
| B4GALNT1 | PCBP3 | 0.736135 | 3 | 0 | 3 |
| B4GALNT1 | SALL4 | 0.732252 | 4 | 0 | 4 |
| B4GALNT1 | C4orf48 | 0.713312 | 4 | 0 | 4 |
| B4GALNT1 | DLGAP1-AS2 | 0.708919 | 3 | 0 | 3 |
| B4GALNT1 | FGFBP2 | 0.70439 | 3 | 0 | 3 |
| B4GALNT1 | WDR66 | 0.699895 | 3 | 0 | 3 |
| B4GALNT1 | NRP2 | 0.699516 | 3 | 0 | 3 |
| B4GALNT1 | WDR54 | 0.696318 | 5 | 0 | 5 |
| B4GALNT1 | COL6A2 | 0.691269 | 4 | 0 | 4 |
| B4GALNT1 | WFIKKN1 | 0.689082 | 3 | 0 | 3 |
| B4GALNT1 | FBLIM1 | 0.678999 | 3 | 0 | 3 |
| B4GALNT1 | IDS | 0.672332 | 3 | 0 | 3 |
| B4GALNT1 | PHLDB2 | 0.667379 | 4 | 0 | 3 |
| B4GALNT1 | CD276 | 0.66499 | 5 | 0 | 4 |
| B4GALNT1 | PTGFRN | 0.664006 | 3 | 0 | 3 |
| B4GALNT1 | ISL2 | 0.663147 | 4 | 0 | 3 |
| B4GALNT1 | LEMD1 | 0.662373 | 4 | 0 | 3 |
| B4GALNT1 | HOXD10 | 0.660199 | 6 | 0 | 6 |
| B4GALNT1 | LINC00942 | 0.658996 | 3 | 0 | 3 |
For details and further investigation, click here
