| Full name: PTPRF interacting protein alpha 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q21.31 | ||
| Entrez ID: 8499 | HGNC ID: HGNC:9246 | Ensembl Gene: ENSG00000139220 | OMIM ID: 603143 |
| Drug and gene relationship at DGIdb | |||
Expression of PPFIA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPFIA2 | 8499 | 206973_at | 0.1006 | 0.8968 | |
| GSE20347 | PPFIA2 | 8499 | 206973_at | -0.0838 | 0.1938 | |
| GSE23400 | PPFIA2 | 8499 | 206973_at | -0.3256 | 0.0000 | |
| GSE26886 | PPFIA2 | 8499 | 206973_at | -0.1056 | 0.4346 | |
| GSE29001 | PPFIA2 | 8499 | 206973_at | -0.2873 | 0.0207 | |
| GSE38129 | PPFIA2 | 8499 | 206973_at | -0.1674 | 0.0183 | |
| GSE45670 | PPFIA2 | 8499 | 206973_at | -0.0938 | 0.3011 | |
| GSE53622 | PPFIA2 | 8499 | 79741 | -0.0533 | 0.7528 | |
| GSE53624 | PPFIA2 | 8499 | 79741 | 0.1730 | 0.2740 | |
| GSE63941 | PPFIA2 | 8499 | 206973_at | -0.2159 | 0.1555 | |
| GSE77861 | PPFIA2 | 8499 | 206973_at | -0.1711 | 0.1439 | |
| SRP133303 | PPFIA2 | 8499 | RNAseq | 0.1745 | 0.5441 | |
| TCGA | PPFIA2 | 8499 | RNAseq | -2.0464 | 0.0005 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PPFIA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPFIA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPFIA2 | 8499 | 2 | 4 | 24 | |
| GSE20123 | PPFIA2 | 8499 | 2 | 4 | 24 | |
| GSE43470 | PPFIA2 | 8499 | 3 | 1 | 39 | |
| GSE46452 | PPFIA2 | 8499 | 9 | 1 | 49 | |
| GSE47630 | PPFIA2 | 8499 | 10 | 1 | 29 | |
| GSE54993 | PPFIA2 | 8499 | 0 | 5 | 65 | |
| GSE54994 | PPFIA2 | 8499 | 7 | 1 | 45 | |
| GSE60625 | PPFIA2 | 8499 | 0 | 0 | 11 | |
| GSE74703 | PPFIA2 | 8499 | 3 | 1 | 32 | |
| GSE74704 | PPFIA2 | 8499 | 1 | 3 | 16 | |
| TCGA | PPFIA2 | 8499 | 18 | 11 | 67 |
Total number of gains: 55; Total number of losses: 32; Total Number of normals: 401.
Somatic mutations of PPFIA2:
Generating mutation plots.
Highly correlated genes for PPFIA2:
Showing top 20/470 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPFIA2 | RABEP2 | 0.790962 | 3 | 0 | 3 |
| PPFIA2 | CYP2F1 | 0.711306 | 4 | 0 | 4 |
| PPFIA2 | DCX | 0.705668 | 3 | 0 | 3 |
| PPFIA2 | TRIM26 | 0.696897 | 3 | 0 | 3 |
| PPFIA2 | C11orf16 | 0.676513 | 3 | 0 | 3 |
| PPFIA2 | ETV2 | 0.675438 | 3 | 0 | 3 |
| PPFIA2 | CEACAM3 | 0.672774 | 4 | 0 | 3 |
| PPFIA2 | SERPINA4 | 0.669405 | 4 | 0 | 4 |
| PPFIA2 | PSG2 | 0.66899 | 3 | 0 | 3 |
| PPFIA2 | CYP2A6 | 0.668146 | 4 | 0 | 3 |
| PPFIA2 | TGM3 | 0.666345 | 3 | 0 | 3 |
| PPFIA2 | FSHR | 0.66597 | 4 | 0 | 4 |
| PPFIA2 | KIR2DS4 | 0.665172 | 4 | 0 | 4 |
| PPFIA2 | INO80D | 0.663172 | 4 | 0 | 4 |
| PPFIA2 | KLK12 | 0.662563 | 3 | 0 | 3 |
| PPFIA2 | ZNF480 | 0.66163 | 3 | 0 | 3 |
| PPFIA2 | PIK3R5 | 0.660432 | 4 | 0 | 4 |
| PPFIA2 | ZNF320 | 0.65774 | 3 | 0 | 3 |
| PPFIA2 | NDUFB2-AS1 | 0.654965 | 4 | 0 | 3 |
| PPFIA2 | DRD5 | 0.652134 | 4 | 0 | 3 |
For details and further investigation, click here
