| Full name: cytochrome P450 family 2 subfamily F member 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 1572 | HGNC ID: HGNC:2632 | Ensembl Gene: ENSG00000197446 | OMIM ID: 124070 |
| Drug and gene relationship at DGIdb | |||
Expression of CYP2F1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYP2F1 | 1572 | 207913_at | 0.0987 | 0.8257 | |
| GSE20347 | CYP2F1 | 1572 | 207913_at | -0.0572 | 0.5909 | |
| GSE23400 | CYP2F1 | 1572 | 207913_at | -0.1581 | 0.0000 | |
| GSE26886 | CYP2F1 | 1572 | 207913_at | -0.0634 | 0.6118 | |
| GSE29001 | CYP2F1 | 1572 | 207913_at | -0.1393 | 0.3908 | |
| GSE38129 | CYP2F1 | 1572 | 207913_at | -0.1565 | 0.0025 | |
| GSE45670 | CYP2F1 | 1572 | 207913_at | -0.0979 | 0.1532 | |
| GSE63941 | CYP2F1 | 1572 | 207913_at | 0.1185 | 0.4044 | |
| GSE77861 | CYP2F1 | 1572 | 207913_at | -0.0543 | 0.6294 | |
| SRP133303 | CYP2F1 | 1572 | RNAseq | 0.0869 | 0.7175 | |
| SRP159526 | CYP2F1 | 1572 | RNAseq | -1.4950 | 0.0127 | |
| TCGA | CYP2F1 | 1572 | RNAseq | 0.9673 | 0.3338 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CYP2F1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CYP2F1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYP2F1 | 1572 | 4 | 4 | 22 | |
| GSE20123 | CYP2F1 | 1572 | 4 | 3 | 23 | |
| GSE43470 | CYP2F1 | 1572 | 3 | 11 | 29 | |
| GSE46452 | CYP2F1 | 1572 | 48 | 1 | 10 | |
| GSE47630 | CYP2F1 | 1572 | 9 | 5 | 26 | |
| GSE54993 | CYP2F1 | 1572 | 17 | 4 | 49 | |
| GSE54994 | CYP2F1 | 1572 | 6 | 11 | 36 | |
| GSE60625 | CYP2F1 | 1572 | 9 | 0 | 2 | |
| GSE74703 | CYP2F1 | 1572 | 3 | 7 | 26 | |
| GSE74704 | CYP2F1 | 1572 | 4 | 1 | 15 | |
| TCGA | CYP2F1 | 1572 | 14 | 16 | 66 |
Total number of gains: 121; Total number of losses: 63; Total Number of normals: 304.
Somatic mutations of CYP2F1:
Generating mutation plots.
Highly correlated genes for CYP2F1:
Showing top 20/340 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYP2F1 | GLYCTK | 0.722199 | 3 | 0 | 3 |
| CYP2F1 | PPFIA2 | 0.711306 | 4 | 0 | 4 |
| CYP2F1 | SH2B1 | 0.707152 | 3 | 0 | 3 |
| CYP2F1 | GRIN2D | 0.700811 | 3 | 0 | 3 |
| CYP2F1 | SOX13 | 0.700436 | 3 | 0 | 3 |
| CYP2F1 | B9D2 | 0.689382 | 4 | 0 | 4 |
| CYP2F1 | PFKL | 0.662677 | 4 | 0 | 3 |
| CYP2F1 | BCL2L1 | 0.657899 | 3 | 0 | 3 |
| CYP2F1 | AMER1 | 0.653762 | 3 | 0 | 3 |
| CYP2F1 | SYNJ2 | 0.652489 | 3 | 0 | 3 |
| CYP2F1 | SLC25A10 | 0.645738 | 4 | 0 | 3 |
| CYP2F1 | FUT7 | 0.643797 | 3 | 0 | 3 |
| CYP2F1 | ADAD2 | 0.641328 | 4 | 0 | 4 |
| CYP2F1 | CCL1 | 0.640377 | 3 | 0 | 3 |
| CYP2F1 | LRCH4 | 0.63879 | 4 | 0 | 4 |
| CYP2F1 | NFKBIB | 0.637982 | 3 | 0 | 3 |
| CYP2F1 | KLK4 | 0.63754 | 3 | 0 | 3 |
| CYP2F1 | TBC1D17 | 0.630975 | 3 | 0 | 3 |
| CYP2F1 | RABEP2 | 0.628535 | 5 | 0 | 5 |
| CYP2F1 | HPS1 | 0.627211 | 3 | 0 | 3 |
For details and further investigation, click here
