| Full name: pregnancy specific beta-1-glycoprotein 2 | Alias Symbol: PSGGB|PSG1|CEA | ||
| Type: protein-coding gene | Cytoband: 19q13.31 | ||
| Entrez ID: 5670 | HGNC ID: HGNC:9519 | Ensembl Gene: ENSG00000242221 | OMIM ID: 176391 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PSG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSG2 | 5670 | 208134_x_at | -0.1569 | 0.5149 | |
| GSE20347 | PSG2 | 5670 | 208134_x_at | -0.0266 | 0.7817 | |
| GSE23400 | PSG2 | 5670 | 208134_x_at | -0.2212 | 0.0000 | |
| GSE26886 | PSG2 | 5670 | 208134_x_at | -0.1981 | 0.0291 | |
| GSE29001 | PSG2 | 5670 | 208134_x_at | -0.3291 | 0.1450 | |
| GSE38129 | PSG2 | 5670 | 208134_x_at | -0.1481 | 0.1144 | |
| GSE45670 | PSG2 | 5670 | 208134_x_at | -0.0215 | 0.9012 | |
| GSE53622 | PSG2 | 5670 | 84850 | 0.4825 | 0.1144 | |
| GSE53624 | PSG2 | 5670 | 84850 | 0.4258 | 0.0436 | |
| GSE63941 | PSG2 | 5670 | 208134_x_at | -0.0025 | 0.9957 | |
| GSE77861 | PSG2 | 5670 | 208134_x_at | -0.1200 | 0.3319 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSG2 | 5670 | 6 | 5 | 19 | |
| GSE20123 | PSG2 | 5670 | 5 | 4 | 21 | |
| GSE43470 | PSG2 | 5670 | 5 | 11 | 27 | |
| GSE46452 | PSG2 | 5670 | 45 | 1 | 13 | |
| GSE47630 | PSG2 | 5670 | 8 | 6 | 26 | |
| GSE54993 | PSG2 | 5670 | 17 | 4 | 49 | |
| GSE54994 | PSG2 | 5670 | 7 | 12 | 34 | |
| GSE60625 | PSG2 | 5670 | 9 | 0 | 2 | |
| GSE74703 | PSG2 | 5670 | 5 | 7 | 24 | |
| GSE74704 | PSG2 | 5670 | 4 | 2 | 14 | |
| TCGA | PSG2 | 5670 | 14 | 15 | 67 |
Total number of gains: 125; Total number of losses: 67; Total Number of normals: 296.
Somatic mutations of PSG2:
Generating mutation plots.
Highly correlated genes for PSG2:
Showing top 20/864 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSG2 | SCGB1D2 | 0.731468 | 3 | 0 | 3 |
| PSG2 | SLC26A8 | 0.705082 | 3 | 0 | 3 |
| PSG2 | ITGB3 | 0.701493 | 4 | 0 | 4 |
| PSG2 | PSG6 | 0.700375 | 7 | 0 | 6 |
| PSG2 | CYP19A1 | 0.697506 | 4 | 0 | 4 |
| PSG2 | RHAG | 0.693807 | 3 | 0 | 3 |
| PSG2 | RPS6KA6 | 0.686211 | 5 | 0 | 5 |
| PSG2 | CBL | 0.680866 | 4 | 0 | 4 |
| PSG2 | GLYAT | 0.677265 | 7 | 0 | 7 |
| PSG2 | CD5L | 0.676082 | 5 | 0 | 5 |
| PSG2 | TCP10L | 0.672329 | 4 | 0 | 4 |
| PSG2 | FGF14 | 0.671837 | 3 | 0 | 3 |
| PSG2 | SCGB1D1 | 0.671308 | 3 | 0 | 3 |
| PSG2 | CER1 | 0.670867 | 5 | 0 | 4 |
| PSG2 | MSH4 | 0.670551 | 4 | 0 | 3 |
| PSG2 | HRC | 0.670159 | 4 | 0 | 4 |
| PSG2 | TEK | 0.669174 | 4 | 0 | 4 |
| PSG2 | ITIH2 | 0.669145 | 4 | 0 | 4 |
| PSG2 | PPFIA2 | 0.66899 | 3 | 0 | 3 |
| PSG2 | ADAMTS12 | 0.666693 | 4 | 0 | 4 |
For details and further investigation, click here
