| Full name: carcinoembryonic antigen related cell adhesion molecule 3 | Alias Symbol: CD66d | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 1084 | HGNC ID: HGNC:1815 | Ensembl Gene: ENSG00000170956 | OMIM ID: 609142 |
| Drug and gene relationship at DGIdb | |||
Expression of CEACAM3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CEACAM3 | 1084 | 208052_x_at | -0.0653 | 0.8655 | |
| GSE20347 | CEACAM3 | 1084 | 208052_x_at | -0.2720 | 0.0022 | |
| GSE23400 | CEACAM3 | 1084 | 208052_x_at | -0.1890 | 0.0000 | |
| GSE26886 | CEACAM3 | 1084 | 208052_x_at | -0.0898 | 0.4391 | |
| GSE29001 | CEACAM3 | 1084 | 208052_x_at | -0.4663 | 0.0046 | |
| GSE38129 | CEACAM3 | 1084 | 208052_x_at | -0.3383 | 0.0001 | |
| GSE45670 | CEACAM3 | 1084 | 208052_x_at | -0.0754 | 0.4524 | |
| GSE53622 | CEACAM3 | 1084 | 106431 | -2.8277 | 0.0000 | |
| GSE53624 | CEACAM3 | 1084 | 106431 | -3.3951 | 0.0000 | |
| GSE63941 | CEACAM3 | 1084 | 208052_x_at | 0.2103 | 0.1237 | |
| GSE77861 | CEACAM3 | 1084 | 208052_x_at | -0.1396 | 0.3992 | |
| GSE97050 | CEACAM3 | 1084 | A_23_P130515 | -0.1730 | 0.8312 | |
| SRP064894 | CEACAM3 | 1084 | RNAseq | -0.8984 | 0.0181 | |
| SRP133303 | CEACAM3 | 1084 | RNAseq | -0.2292 | 0.5831 | |
| SRP159526 | CEACAM3 | 1084 | RNAseq | -1.3739 | 0.1804 | |
| TCGA | CEACAM3 | 1084 | RNAseq | -0.6380 | 0.3063 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CEACAM3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CEACAM3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CEACAM3 | 1084 | 4 | 4 | 22 | |
| GSE20123 | CEACAM3 | 1084 | 4 | 3 | 23 | |
| GSE43470 | CEACAM3 | 1084 | 3 | 11 | 29 | |
| GSE46452 | CEACAM3 | 1084 | 48 | 1 | 10 | |
| GSE47630 | CEACAM3 | 1084 | 9 | 5 | 26 | |
| GSE54993 | CEACAM3 | 1084 | 17 | 4 | 49 | |
| GSE54994 | CEACAM3 | 1084 | 7 | 12 | 34 | |
| GSE60625 | CEACAM3 | 1084 | 9 | 0 | 2 | |
| GSE74703 | CEACAM3 | 1084 | 3 | 7 | 26 | |
| GSE74704 | CEACAM3 | 1084 | 4 | 1 | 15 | |
| TCGA | CEACAM3 | 1084 | 15 | 15 | 66 |
Total number of gains: 123; Total number of losses: 63; Total Number of normals: 302.
Somatic mutations of CEACAM3:
Generating mutation plots.
Highly correlated genes for CEACAM3:
Showing top 20/1321 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CEACAM3 | TMPRSS11A | 0.886148 | 3 | 0 | 3 |
| CEACAM3 | NCCRP1 | 0.880273 | 3 | 0 | 3 |
| CEACAM3 | CNFN | 0.859459 | 3 | 0 | 3 |
| CEACAM3 | OTOP3 | 0.855589 | 3 | 0 | 3 |
| CEACAM3 | SPRR2A | 0.839232 | 3 | 0 | 3 |
| CEACAM3 | SPRR2F | 0.838175 | 3 | 0 | 3 |
| CEACAM3 | SPRR2E | 0.823766 | 3 | 0 | 3 |
| CEACAM3 | SDCBP2 | 0.81667 | 3 | 0 | 3 |
| CEACAM3 | SPRR2D | 0.815291 | 3 | 0 | 3 |
| CEACAM3 | FAM163B | 0.809265 | 3 | 0 | 3 |
| CEACAM3 | CYP3A7 | 0.788838 | 3 | 0 | 3 |
| CEACAM3 | PRSS27 | 0.787261 | 4 | 0 | 3 |
| CEACAM3 | LIPH | 0.784804 | 4 | 0 | 4 |
| CEACAM3 | MUC22 | 0.7819 | 3 | 0 | 3 |
| CEACAM3 | KRTAP20-1 | 0.77278 | 3 | 0 | 3 |
| CEACAM3 | MFSD2B | 0.766943 | 3 | 0 | 3 |
| CEACAM3 | ARHGAP27 | 0.760155 | 3 | 0 | 3 |
| CEACAM3 | KPRP | 0.757279 | 3 | 0 | 3 |
| CEACAM3 | ARHGAP40 | 0.750489 | 3 | 0 | 3 |
| CEACAM3 | OR2Z1 | 0.747144 | 3 | 0 | 3 |
For details and further investigation, click here
